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- W3040840992 abstract "Topochemical assembly carbon materials with unique structure rarely investigated and reported. Herein, we demonstrate the feasibility of using topochemical assembly levodopa nanoparticles with dendritic structure (LNDS) network as a new high-performance biosensing platform based on noncovalent functionalization of LNDS with a fluorescent oligonucleotide. The proposed platform is dependent on the competition of π-π stacking and electrostatic repulsion interactions between LNDS and fluorescent oligonucleotide. The obtained LNDS with 96.1% quenching efficiency is synthesized by using levodopa as the single precursor by natural oxidation or microwave irradiation. The constructed platform can be used for simple and efficient probing single-nucleotide polymorphisms (SNPs) and cDNA by fluorescence restoration with a highly sensitivity and selectivity, remarkably superior to those based on graphenes. Additionally, an aptasensor is further constructed for small molecule ATP detention in serum with a low detection limit of 4 μM. To the best of our knowledge, this is the first attempt to use LNDS to design a biosensing platform, and therefore opens possibilities for new types of nanoparticle-based molecule approaches, and sequencing technologies." @default.
- W3040840992 created "2020-07-16" @default.
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- W3040840992 date "2020-11-01" @default.
- W3040840992 modified "2023-10-17" @default.
- W3040840992 title "Topochemical assembly of levodopa nanoparticles network as a high-performance biosensing platform coupling with π-π stacking and electrostatic repulsion interactions" @default.
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- W3040840992 doi "https://doi.org/10.1016/j.talanta.2020.121285" @default.
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