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- W3040862057 abstract "Abstract Background Primary lymphedema is an anomaly of the regional lymphatic system with long symptom duration or severe lymphatic obstruction. Few microsurgical treatments for primary lymphedema have been reported. This aim of this study was to investigate the outcomes of microsurgical treatments in pediatric primary lymphedema patients. Methods Between 2013 and 2017, pediatric primary lymphedema patients who underwent either lymphovenous anastomosis (LVA) or vascularized lymph node transfer (VLNT) were retrospectively reviewed. Cheng's Lymphedema Grading, Taiwan Lymphoscintigraphy Staging and indocyanine green lymphography were used to select the procedures. No compression garments were used postoperatively. Outcome measurements included circumferential difference, episodes of cellulitis, and Lymphedema‐specific Quality of life questionnaire (LYMQoL). Results Nine patients with mean age of 9.2 years (range, 2–19 years) with 11 lower and two upper lymphedematous limbs underwent 11 VLNT and two LVA. All VLNT flaps survived. At a mean 38.4‐months (range, 16–63 months) of follow‐up, the mean circumferential difference in nine unilateral lymphedematous limbs was improved by 6.7 ± 9.9% ( p = .066). Two patients with bilateral lower limb lymphedema had mean limb circumference improvements of 1.3 and 6.5 cm, respectively. In nine limbs with cellulitis preoperatively, episodes of cellulitis decreased by 2.67 times/year ( p = .007). At a mean 22.3‐months of follow‐up (range, 13–24 months), the LYMQoL overall score in 6 patients older than 7 years was improved by 3.2 ± 1.1 points ( p = .007). Conclusions Lymphedema microsurgery significantly improved the episodes of cellulitis and quality of life without utilizing compression garments in pediatric primary lymphedema patients." @default.
- W3040862057 created "2020-07-16" @default.
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- W3040862057 date "2020-07-11" @default.
- W3040862057 modified "2023-10-06" @default.
- W3040862057 title "Lymphedema microsurgery improved outcomes of pediatric primary extremity lymphedema" @default.
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- W3040862057 doi "https://doi.org/10.1002/micr.30622" @default.
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