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- W3040896576 abstract "Herein, we present the case of a female with co-occurring chronic lymphocytic leukemia (CLL) and metastatic ER/PR-positive breast cancer, who when taken off palbociclib for severe neutropenia and infectious complications, experienced rebound lymphocytosis. Though this was ultimately a benign clinical outcome, it exemplifies how CDK4/6 inhibitors induce a cell cycle arrest by decreasing the proliferation of hematopoietic stem cells (HSC), in this case CLL cells, with recovery of counts once drug is stopped." @default.
- W3040896576 created "2020-07-16" @default.
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- W3040896576 date "2020-07-08" @default.
- W3040896576 modified "2023-09-25" @default.
- W3040896576 title "Rebound lymphocytosis in a patient with chronic lymphocytic leukemia after cessation of a CDK 4/6 inhibitor for concomitant breast cancer" @default.
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- W3040896576 doi "https://doi.org/10.1111/tbj.13955" @default.
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