Matches in SemOpenAlex for { <https://semopenalex.org/work/W3041277892> ?p ?o ?g. }
Showing items 1 to 74 of
74
with 100 items per page.
- W3041277892 startingPage "01" @default.
- W3041277892 abstract "Biomaterial scaffolds engineered to promote osteogenesis which can subsequently remodel in an identical fashion to that of natural tissue, is an excellent clinical strategy for treating the defects of bone in the maxillofacial region. This study has developed, using a novel melt electrowriting (MEW) technique, various graded porous polycaprolactone (PCL) scaffolds able to imitate the bimodal structure of cortical and cancellous bone tissue in terms of their morphological pore structure. These scaffolds were subsequently shown to facilitate the proliferation of osteoblasts with significant alkaline phosphatase (ALP) activity. Scaffolds with a staggered architecture i.e. those where the corresponding fibers in different layers are offset horizontally during the printing process, increases the number of contact points, enables larger pores, facilitates cell attachment and creates a highly porous structure with interconnected networks favourable for improved cell migration and vascularization. MEW is a relatively new technology that fills a gap between conventional fused deposition modelling 3D printing and solution electrospinning by affording significantly better control over the fabrication of the porosity in scaffolds. This is due to the highresolution during printing of the fibers which enables small pore sizes in the desired porosity. PCL polymer with its advantages of less immunoreactivity following implantation and mechanically suitability for the support of bone cells, has flexibility in design and is widely used in bone applications. However poor bioactivity and cellular affinity as well aslong-term degradation issues with PCL have been reported." @default.
- W3041277892 created "2020-07-16" @default.
- W3041277892 creator A5064969433 @default.
- W3041277892 date "2020-01-01" @default.
- W3041277892 modified "2023-09-26" @default.
- W3041277892 title "Effect of Offset/ Gradient melt electrowritten (MEW) PCL scaffolds in bone regeneration" @default.
- W3041277892 hasPublicationYear "2020" @default.
- W3041277892 type Work @default.
- W3041277892 sameAs 3041277892 @default.
- W3041277892 citedByCount "0" @default.
- W3041277892 crossrefType "journal-article" @default.
- W3041277892 hasAuthorship W3041277892A5064969433 @default.
- W3041277892 hasConcept C105702510 @default.
- W3041277892 hasConcept C136229726 @default.
- W3041277892 hasConcept C136525101 @default.
- W3041277892 hasConcept C142724271 @default.
- W3041277892 hasConcept C144796933 @default.
- W3041277892 hasConcept C159985019 @default.
- W3041277892 hasConcept C171250308 @default.
- W3041277892 hasConcept C192562407 @default.
- W3041277892 hasConcept C204787440 @default.
- W3041277892 hasConcept C2776350087 @default.
- W3041277892 hasConcept C2778414984 @default.
- W3041277892 hasConcept C2778606738 @default.
- W3041277892 hasConcept C2779868350 @default.
- W3041277892 hasConcept C521977710 @default.
- W3041277892 hasConcept C6648577 @default.
- W3041277892 hasConcept C71924100 @default.
- W3041277892 hasConceptScore W3041277892C105702510 @default.
- W3041277892 hasConceptScore W3041277892C136229726 @default.
- W3041277892 hasConceptScore W3041277892C136525101 @default.
- W3041277892 hasConceptScore W3041277892C142724271 @default.
- W3041277892 hasConceptScore W3041277892C144796933 @default.
- W3041277892 hasConceptScore W3041277892C159985019 @default.
- W3041277892 hasConceptScore W3041277892C171250308 @default.
- W3041277892 hasConceptScore W3041277892C192562407 @default.
- W3041277892 hasConceptScore W3041277892C204787440 @default.
- W3041277892 hasConceptScore W3041277892C2776350087 @default.
- W3041277892 hasConceptScore W3041277892C2778414984 @default.
- W3041277892 hasConceptScore W3041277892C2778606738 @default.
- W3041277892 hasConceptScore W3041277892C2779868350 @default.
- W3041277892 hasConceptScore W3041277892C521977710 @default.
- W3041277892 hasConceptScore W3041277892C6648577 @default.
- W3041277892 hasConceptScore W3041277892C71924100 @default.
- W3041277892 hasIssue "2" @default.
- W3041277892 hasLocation W30412778921 @default.
- W3041277892 hasOpenAccess W3041277892 @default.
- W3041277892 hasPrimaryLocation W30412778921 @default.
- W3041277892 hasRelatedWork W1607529917 @default.
- W3041277892 hasRelatedWork W1974025445 @default.
- W3041277892 hasRelatedWork W1992373055 @default.
- W3041277892 hasRelatedWork W1993172698 @default.
- W3041277892 hasRelatedWork W2060751157 @default.
- W3041277892 hasRelatedWork W2166848493 @default.
- W3041277892 hasRelatedWork W2245805814 @default.
- W3041277892 hasRelatedWork W2611537850 @default.
- W3041277892 hasRelatedWork W2774965031 @default.
- W3041277892 hasRelatedWork W2804491020 @default.
- W3041277892 hasRelatedWork W2889562668 @default.
- W3041277892 hasRelatedWork W2911308928 @default.
- W3041277892 hasRelatedWork W2947333719 @default.
- W3041277892 hasRelatedWork W3000731236 @default.
- W3041277892 hasRelatedWork W3027635215 @default.
- W3041277892 hasRelatedWork W3036121931 @default.
- W3041277892 hasRelatedWork W3100232185 @default.
- W3041277892 hasRelatedWork W3148248825 @default.
- W3041277892 hasRelatedWork W3182671912 @default.
- W3041277892 hasRelatedWork W834970807 @default.
- W3041277892 hasVolume "3" @default.
- W3041277892 isParatext "false" @default.
- W3041277892 isRetracted "false" @default.
- W3041277892 magId "3041277892" @default.
- W3041277892 workType "article" @default.