Matches in SemOpenAlex for { <https://semopenalex.org/work/W3041569897> ?p ?o ?g. }
Showing items 1 to 100 of
100
with 100 items per page.
- W3041569897 endingPage "473" @default.
- W3041569897 startingPage "464" @default.
- W3041569897 abstract "Purpose of review Functional mitral regurgitation (FMR) is a complex condition in which significant mitral regurgitation coexist with cardiomyopathy and heart failure and carries an increased risk for associated morbidity and mortality. In addition to guideline-directed medical therapy and cardiac resynchronization therapy, percutaneous transcatheter mitral valve repair (TMVr) is a new therapeutic option but requires careful selection of the proper candidates. We describe the different mechanisms of functional mitral regurgitation, review echocardiographic parameters to assess its severity, and discuss recently published relevant studies including TMVr. Recent findings Two randomized controlled trials assessing the efficacy and safety of TMVr using the MitraClip in patients with heart failure and severe functional mitral regurgitation were published: MITRA-FR (Percutaneous Repair with the MitraClip Device for Severe Functional/Secondary Mitral Regurgitation) and COAPT (Cardiovascular Outcomes Assessment of the MitraClip Percutaneous Therapy for Heart Failure Patients with Functional Mitral Regurgitation). The results of these trials were opposite: although MITRA-FR failed to show clinical benefit, COAPT showed a dramatic clinical and echocardiographic benefit from transcatheter mitral valve repair using the MitraClip device. We discuss these two important trials and how differences in patient enrollment could explain the discrepant results and the manner they may influence future studies and clinical practice. Summary Patients with FMR receiving optimal guideline-directed medical therapy and cardiac resynchronization therapy who meet specific clinical and echocardiographic criteria can benefit from transcatheter mitral valve repair." @default.
- W3041569897 created "2020-07-16" @default.
- W3041569897 creator A5022793523 @default.
- W3041569897 creator A5058664452 @default.
- W3041569897 date "2020-07-07" @default.
- W3041569897 modified "2023-10-16" @default.
- W3041569897 title "Functional mitral regurgitation" @default.
- W3041569897 cites W168038522 @default.
- W3041569897 cites W1880802948 @default.
- W3041569897 cites W2032439547 @default.
- W3041569897 cites W2041867286 @default.
- W3041569897 cites W2045006267 @default.
- W3041569897 cites W2047529056 @default.
- W3041569897 cites W2079710389 @default.
- W3041569897 cites W2101825249 @default.
- W3041569897 cites W2111183899 @default.
- W3041569897 cites W2122694177 @default.
- W3041569897 cites W2142960358 @default.
- W3041569897 cites W2146521529 @default.
- W3041569897 cites W2148226732 @default.
- W3041569897 cites W2149571274 @default.
- W3041569897 cites W2153219359 @default.
- W3041569897 cites W2158671861 @default.
- W3041569897 cites W2160995044 @default.
- W3041569897 cites W2193849676 @default.
- W3041569897 cites W2315476483 @default.
- W3041569897 cites W2596797126 @default.
- W3041569897 cites W2596816418 @default.
- W3041569897 cites W2614960675 @default.
- W3041569897 cites W2736933202 @default.
- W3041569897 cites W2750101675 @default.
- W3041569897 cites W2751630023 @default.
- W3041569897 cites W2753637555 @default.
- W3041569897 cites W2795624029 @default.
- W3041569897 cites W2888290077 @default.
- W3041569897 cites W2889688444 @default.
- W3041569897 cites W2975804153 @default.
- W3041569897 cites W3008747247 @default.
- W3041569897 cites W3021792137 @default.
- W3041569897 cites W4205993996 @default.
- W3041569897 cites W4206381626 @default.
- W3041569897 cites W4211222990 @default.
- W3041569897 doi "https://doi.org/10.1097/hco.0000000000000770" @default.
- W3041569897 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32649357" @default.
- W3041569897 hasPublicationYear "2020" @default.
- W3041569897 type Work @default.
- W3041569897 sameAs 3041569897 @default.
- W3041569897 citedByCount "0" @default.
- W3041569897 crossrefType "journal-article" @default.
- W3041569897 hasAuthorship W3041569897A5022793523 @default.
- W3041569897 hasAuthorship W3041569897A5058664452 @default.
- W3041569897 hasConcept C126322002 @default.
- W3041569897 hasConcept C142724271 @default.
- W3041569897 hasConcept C164705383 @default.
- W3041569897 hasConcept C2776034619 @default.
- W3041569897 hasConcept C2777543888 @default.
- W3041569897 hasConcept C2778198053 @default.
- W3041569897 hasConcept C2780182762 @default.
- W3041569897 hasConcept C2780679668 @default.
- W3041569897 hasConcept C2780793704 @default.
- W3041569897 hasConcept C2909944400 @default.
- W3041569897 hasConcept C2993373945 @default.
- W3041569897 hasConcept C535046627 @default.
- W3041569897 hasConcept C71924100 @default.
- W3041569897 hasConcept C78085059 @default.
- W3041569897 hasConceptScore W3041569897C126322002 @default.
- W3041569897 hasConceptScore W3041569897C142724271 @default.
- W3041569897 hasConceptScore W3041569897C164705383 @default.
- W3041569897 hasConceptScore W3041569897C2776034619 @default.
- W3041569897 hasConceptScore W3041569897C2777543888 @default.
- W3041569897 hasConceptScore W3041569897C2778198053 @default.
- W3041569897 hasConceptScore W3041569897C2780182762 @default.
- W3041569897 hasConceptScore W3041569897C2780679668 @default.
- W3041569897 hasConceptScore W3041569897C2780793704 @default.
- W3041569897 hasConceptScore W3041569897C2909944400 @default.
- W3041569897 hasConceptScore W3041569897C2993373945 @default.
- W3041569897 hasConceptScore W3041569897C535046627 @default.
- W3041569897 hasConceptScore W3041569897C71924100 @default.
- W3041569897 hasConceptScore W3041569897C78085059 @default.
- W3041569897 hasIssue "5" @default.
- W3041569897 hasLocation W30415698971 @default.
- W3041569897 hasOpenAccess W3041569897 @default.
- W3041569897 hasPrimaryLocation W30415698971 @default.
- W3041569897 hasRelatedWork W2022164691 @default.
- W3041569897 hasRelatedWork W2080505826 @default.
- W3041569897 hasRelatedWork W2413650273 @default.
- W3041569897 hasRelatedWork W2549444212 @default.
- W3041569897 hasRelatedWork W2616407618 @default.
- W3041569897 hasRelatedWork W2766997004 @default.
- W3041569897 hasRelatedWork W2936646214 @default.
- W3041569897 hasRelatedWork W3012167596 @default.
- W3041569897 hasRelatedWork W3041569897 @default.
- W3041569897 hasRelatedWork W3217010453 @default.
- W3041569897 hasVolume "35" @default.
- W3041569897 isParatext "false" @default.
- W3041569897 isRetracted "false" @default.
- W3041569897 magId "3041569897" @default.
- W3041569897 workType "article" @default.