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• W3041726267 abstract "An efficient synthesis of tetrahydroquinolines using silica iodide as heterogeneous catalyst. Ethyl acetoacetate, dimedone, ammonium acetate with suitable aromatic aldehydes in ethanol was reported. Silica iodide (SiO2–I) acts as an efficient heterogeneous catalyst to afford the products in excellent yield in short reaction duration and reusable catalyst. The synthesized 4 d and 4 h compounds were characterized by the single crystal X-ray diffraction method. Further, the prepared quinoline derivatives showed potent anti-cancer activity against HepG2 and MCF-7 cell lines. Docking study was carried out to evaluate the binding affinity of the synthesized compounds and the standard drug doxorubicin with Estrogen Receptor (ER)." @default.
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• W3041726267 date "2020-12-01" @default.
• W3041726267 modified "2023-09-27" @default.
• W3041726267 title "Synthesis, characterization, crystal structure and anticancer activity of tetrahydro-quinolines using silica iodide as a heterogeneous catalyst" @default.
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• W3041726267 doi "https://doi.org/10.1016/j.molstruc.2020.128790" @default.
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