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• W3041836245 endingPage "2180" @default.
• W3041836245 startingPage "2180" @default.
• W3041836245 abstract "Novel drugs have improved survival for patients with multiple myeloma in recent years. However, the disease is still fatal. Allogeneic stem cell transplantation (Allo) has proven to cure some patients with the disease, but its role is controversial due to relatively high transplant-related toxicity and mortality (nonrelapse mortality, NRM). Using nonmyeloablative reduced-intensity conditioning (RIC), both toxicity and NRM can be reduced, and RICAllo is, therefore, an option for subgroups of patients. Upfront tandem autologous/RICAllo (Auto/RICAllo) was shown to be superior to single Auto or tandem Auto/Auto in both progression-free (PFS) and overall survival (OS) in two prospective studies with long-term follow-up, while three similarly designed studies did not detect a difference. A recent update of pooled patient data from four of these studies showed significantly superior PFS and OS with Auto/RICAllo. Importantly, none of these studies showed inferior results with Auto/RICAllo in patients less than 70 years of age. Auto/RICAllo appears to overcome some poor risk cytogenetic markers. Encouraging results have also been seen in treatment of relapsed patients. Combining Allo with new proteasome inhibitors and immunomodulatory drugs may further improve results. Other encouraging new cell therapies such as with CAR T-cells, NK- and CAR NK-cells may well have a place in combination with RICAllo. Such studies are warranted." @default.
• W3041836245 created "2020-07-16" @default.
• W3041836245 creator A5024780153 @default.
• W3041836245 creator A5026970655 @default.
• W3041836245 creator A5050987906 @default.
• W3041836245 creator A5066284854 @default.
• W3041836245 creator A5076651597 @default.
• W3041836245 date "2020-07-10" @default.
• W3041836245 modified "2023-10-18" @default.
• W3041836245 title "Allogeneic Transplantation in Multiple Myeloma—Does It Still Have a Place?" @default.
• W3041836245 cites W121638319 @default.
• W3041836245 cites W1539462333 @default.
• W3041836245 cites W1563095448 @default.
• W3041836245 cites W1828155201 @default.
• W3041836245 cites W1914208484 @default.
• W3041836245 cites W1914496726 @default.
• W3041836245 cites W193514409 @default.
• W3041836245 cites W1959587708 @default.
• W3041836245 cites W1963700539 @default.
• W3041836245 cites W1965280159 @default.
• W3041836245 cites W1968578379 @default.
• W3041836245 cites W1969349875 @default.
• W3041836245 cites W1977390830 @default.
• W3041836245 cites W1978377409 @default.
• W3041836245 cites W1982412132 @default.
• W3041836245 cites W1982946267 @default.
• W3041836245 cites W1991026262 @default.
• W3041836245 cites W2002324468 @default.
• W3041836245 cites W2010766702 @default.
• W3041836245 cites W2012665806 @default.
• W3041836245 cites W2021977368 @default.
• W3041836245 cites W2022877662 @default.
• W3041836245 cites W2024733207 @default.
• W3041836245 cites W2031686134 @default.
• W3041836245 cites W2034236066 @default.
• W3041836245 cites W2035600195 @default.
• W3041836245 cites W2035800776 @default.
• W3041836245 cites W2043256280 @default.
• W3041836245 cites W2044186255 @default.
• W3041836245 cites W2048454989 @default.
• W3041836245 cites W2049498583 @default.
• W3041836245 cites W2057831000 @default.
• W3041836245 cites W2060302368 @default.
• W3041836245 cites W2060795740 @default.
• W3041836245 cites W2060957671 @default.
• W3041836245 cites W2067484665 @default.
• W3041836245 cites W2069450217 @default.
• W3041836245 cites W2075729465 @default.
• W3041836245 cites W2076153347 @default.
• W3041836245 cites W2078038472 @default.
• W3041836245 cites W2086735887 @default.
• W3041836245 cites W2087613277 @default.
• W3041836245 cites W2087843841 @default.
• W3041836245 cites W2091957777 @default.
• W3041836245 cites W2095019788 @default.
• W3041836245 cites W2100533205 @default.
• W3041836245 cites W2101380981 @default.
• W3041836245 cites W2101761743 @default.
• W3041836245 cites W2103255433 @default.
• W3041836245 cites W2104200322 @default.
• W3041836245 cites W2117648349 @default.
• W3041836245 cites W2119969066 @default.
• W3041836245 cites W2122021478 @default.
• W3041836245 cites W2126427465 @default.
• W3041836245 cites W2130884024 @default.
• W3041836245 cites W2131837746 @default.
• W3041836245 cites W2133871976 @default.
• W3041836245 cites W2134592456 @default.
• W3041836245 cites W2134877860 @default.
• W3041836245 cites W2137062141 @default.
• W3041836245 cites W2141451077 @default.
• W3041836245 cites W2145651125 @default.
• W3041836245 cites W2153472639 @default.
• W3041836245 cites W2153614907 @default.
• W3041836245 cites W2155535356 @default.
• W3041836245 cites W2159773146 @default.
• W3041836245 cites W2161702482 @default.
• W3041836245 cites W2162583751 @default.
• W3041836245 cites W2169288585 @default.
• W3041836245 cites W2323225735 @default.
• W3041836245 cites W2325022302 @default.
• W3041836245 cites W2397983925 @default.
• W3041836245 cites W2417033282 @default.
• W3041836245 cites W2508231867 @default.
• W3041836245 cites W2525489874 @default.
• W3041836245 cites W2550213025 @default.
• W3041836245 cites W2604776612 @default.
• W3041836245 cites W2605568553 @default.
• W3041836245 cites W2611637210 @default.
• W3041836245 cites W2613327076 @default.
• W3041836245 cites W2732694723 @default.
• W3041836245 cites W2763322898 @default.
• W3041836245 cites W2763858024 @default.
• W3041836245 cites W2765918174 @default.
• W3041836245 cites W2793656478 @default.
• W3041836245 cites W2799411147 @default.
• W3041836245 cites W2889808350 @default.
• W3041836245 cites W2891966018 @default.

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