FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3042012603> ?p ?o ?g. }

• W3042012603 abstract "Abstract Helicobacter pylori is a gram-negative, spiral-shaped bacterial pathogen and the causative agent for gastritis, peptic ulcer disease and classified as a WHO class I carcinogen. While the prevalence of H. pylori infections in Africa is among the highest in the world, the incidence of gastric cancer is comparably low. Little is known about other symptoms related to the H. pylori infection in Africa and the association with certain phenotypes of bacterial virulence. We established a network of study sites in Nigeria (NG) and South Africa (ZA) to gain an overview on the epidemiological situation. In total 220 isolates from 114 patients were analyzed and 118 different patient isolates examined for the presence of the virulence factors cagA, vacA, dupA , their phylogenetic origin and their resistance against the commonly used antibiotics amoxicillin, clarithromycin, metronidazole and tetracycline. We report that H. pylori isolates from Nigeria and South Africa differ significantly in their phylogenetic profiles and in their expression of virulence factors. VacA mosaicism is intensive, resulting in m1-m2 vacA chimeras and frequent s1m1 and s1m2 vacA subtypes in hpAfrica2 strains. Gastric lesions were diagnosed more frequent in Nigerian versus South African patients and H. pylori isolates that are resistant against one or multiple antibiotics occur frequently in both countries." @default.
• W3042012603 created "2020-07-16" @default.
• W3042012603 creator A5000203419 @default.
• W3042012603 creator A5010091845 @default.
• W3042012603 creator A5014048581 @default.
• W3042012603 creator A5023290530 @default.
• W3042012603 creator A5026388539 @default.
• W3042012603 creator A5029819126 @default.
• W3042012603 creator A5030652952 @default.
• W3042012603 creator A5032778658 @default.
• W3042012603 creator A5035772670 @default.
• W3042012603 creator A5046776637 @default.
• W3042012603 creator A5048045295 @default.
• W3042012603 creator A5049381493 @default.
• W3042012603 creator A5057526291 @default.
• W3042012603 creator A5068383348 @default.
• W3042012603 creator A5077244723 @default.
• W3042012603 creator A5077658794 @default.
• W3042012603 creator A5088142484 @default.
• W3042012603 creator A5090109879 @default.
• W3042012603 creator A5091016099 @default.
• W3042012603 date "2020-07-10" @default.
• W3042012603 modified "2023-10-01" @default.
• W3042012603 title "Helicobacter pylori patient isolates from South Africa and Nigeria differ in virulence factor pathogenicity profile and associated gastric disease outcome" @default.
• W3042012603 cites W1276209945 @default.
• W3042012603 cites W1500891430 @default.
• W3042012603 cites W1621166403 @default.
• W3042012603 cites W1751616587 @default.
• W3042012603 cites W1974150948 @default.
• W3042012603 cites W1980975685 @default.
• W3042012603 cites W1996521911 @default.
• W3042012603 cites W2011509507 @default.
• W3042012603 cites W2016299826 @default.
• W3042012603 cites W2018087951 @default.
• W3042012603 cites W2020684814 @default.
• W3042012603 cites W2025026187 @default.
• W3042012603 cites W2025675262 @default.
• W3042012603 cites W2036173432 @default.
• W3042012603 cites W2044025776 @default.
• W3042012603 cites W2045445355 @default.
• W3042012603 cites W2054312992 @default.
• W3042012603 cites W2054778956 @default.
• W3042012603 cites W2062361055 @default.
• W3042012603 cites W2076770799 @default.
• W3042012603 cites W2088902653 @default.
• W3042012603 cites W2094273148 @default.
• W3042012603 cites W2099499298 @default.
• W3042012603 cites W2101366809 @default.
• W3042012603 cites W2108018752 @default.
• W3042012603 cites W2122933597 @default.
• W3042012603 cites W2128191862 @default.
• W3042012603 cites W2147496191 @default.
• W3042012603 cites W2147825355 @default.
• W3042012603 cites W2152634089 @default.
• W3042012603 cites W2158011294 @default.
• W3042012603 cites W2160541779 @default.
• W3042012603 cites W2165505839 @default.
• W3042012603 cites W2180752973 @default.
• W3042012603 cites W2231020797 @default.
• W3042012603 cites W2331971827 @default.
• W3042012603 cites W2427391176 @default.
• W3042012603 cites W2527848138 @default.
• W3042012603 cites W2609752905 @default.
• W3042012603 cites W2610535007 @default.
• W3042012603 cites W2749472576 @default.
• W3042012603 cites W2763597855 @default.
• W3042012603 cites W2785135020 @default.
• W3042012603 cites W2799524357 @default.
• W3042012603 cites W2803849204 @default.
• W3042012603 cites W2809139991 @default.
• W3042012603 cites W2890918697 @default.
• W3042012603 cites W2935703421 @default.
• W3042012603 cites W2948387191 @default.
• W3042012603 cites W2963258851 @default.
• W3042012603 doi "https://doi.org/10.1038/s41598-020-66128-0" @default.
• W3042012603 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7351988" @default.
• W3042012603 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32651394" @default.
• W3042012603 hasPublicationYear "2020" @default.
• W3042012603 type Work @default.
• W3042012603 sameAs 3042012603 @default.
• W3042012603 citedByCount "11" @default.
• W3042012603 countsByYear W30420126032020 @default.
• W3042012603 countsByYear W30420126032021 @default.
• W3042012603 countsByYear W30420126032022 @default.
• W3042012603 countsByYear W30420126032023 @default.
• W3042012603 crossrefType "journal-article" @default.
• W3042012603 hasAuthorship W3042012603A5000203419 @default.
• W3042012603 hasAuthorship W3042012603A5010091845 @default.
• W3042012603 hasAuthorship W3042012603A5014048581 @default.
• W3042012603 hasAuthorship W3042012603A5023290530 @default.
• W3042012603 hasAuthorship W3042012603A5026388539 @default.
• W3042012603 hasAuthorship W3042012603A5029819126 @default.
• W3042012603 hasAuthorship W3042012603A5030652952 @default.
• W3042012603 hasAuthorship W3042012603A5032778658 @default.
• W3042012603 hasAuthorship W3042012603A5035772670 @default.
• W3042012603 hasAuthorship W3042012603A5046776637 @default.
• W3042012603 hasAuthorship W3042012603A5048045295 @default.
• W3042012603 hasAuthorship W3042012603A5049381493 @default.
• W3042012603 hasAuthorship W3042012603A5057526291 @default.
• W3042012603 hasAuthorship W3042012603A5068383348 @default.

• next