FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3042133452> ?p ?o ?g. }

• W3042133452 endingPage "826" @default.
• W3042133452 startingPage "819" @default.
• W3042133452 abstract "The usefulness of β-blockers has been questioned for patients who have hypertension without a prior manifestation of coronary heart disease or heart failure. In addition, sex-based differences in the efficacy of β-blockers for prevention of heart failure during acute myocardial ischemia have never been evaluated. We explored whether the effect of β-blocker therapy varied according to the sex among patients with hypertension who have no prior history of cardiovascular disease. Data were drawn from the ISACS (International Survey of Acute Coronary Syndromes)-Archives. The study population consisted of 13 764 patients presenting with acute coronary syndromes. There were 2590 patients in whom hypertension was treated previously with β-blocker (954 women and 1636 men). Primary outcome measure was the incidence of heart failure according to Killip class classification. Subsidiary analyses were conducted to estimate the association between heart failure and all-cause mortality at 30 days. Outcome rates were assessed using the inverse probability of treatment weighting and logistic regression models. Estimates were compared by test of interaction on the log scale. Among patients taking β-blockers before admission, there was an absolute difference of 4.6% between women and men in the rate of heart failure (Killip ≥2) at hospital presentation (21.3% versus 16.7%; relative risk ratio, 1.35 [95% CI, 1.10–1.65]). On the opposite, the rate of heart failure was approximately similar among women and men who did not receive β-blockers (17.2% versus 16.1%; relative risk ratio, 1.09 [95% CI, 0.97–1.21]). The test of interaction identified a significant ( P =0.034) association between sex and β-blocker therapy. Heart failure was predictive of mortality at 30-day either in women (odds ratio, 7.54 [95% CI, 5.78–9.83]) or men (odds ratio, 9.62 [95% CI, 7.67–12.07]). In conclusion, β-blockers use may be an acute precipitant of heart failure in new-onset coronary heart disease among women, but not men. Heart failure increases the risk of death. Registration URL: https://www.clinicaltrials.gov . Unique identifier: NCT04008173." @default.
• W3042133452 created "2020-07-16" @default.
• W3042133452 creator A5002289527 @default.
• W3042133452 creator A5004801541 @default.
• W3042133452 creator A5011468924 @default.
• W3042133452 creator A5012339002 @default.
• W3042133452 creator A5024483983 @default.
• W3042133452 creator A5049648116 @default.
• W3042133452 creator A5054578676 @default.
• W3042133452 creator A5059500249 @default.
• W3042133452 creator A5073951189 @default.
• W3042133452 creator A5081510830 @default.
• W3042133452 creator A5089266175 @default.
• W3042133452 date "2020-09-01" @default.
• W3042133452 modified "2023-10-13" @default.
• W3042133452 title "Prior Beta-Blocker Therapy for Hypertension and Sex-Based Differences in Heart Failure Among Patients With Incident Coronary Heart Disease" @default.
• W3042133452 cites W1497461844 @default.
• W3042133452 cites W1600041372 @default.
• W3042133452 cites W1972320908 @default.
• W3042133452 cites W1994906722 @default.
• W3042133452 cites W2009741254 @default.
• W3042133452 cites W2020468542 @default.
• W3042133452 cites W2023515446 @default.
• W3042133452 cites W2040888535 @default.
• W3042133452 cites W2043254260 @default.
• W3042133452 cites W206590124 @default.
• W3042133452 cites W207511860 @default.
• W3042133452 cites W2102262001 @default.
• W3042133452 cites W2110818436 @default.
• W3042133452 cites W2114333967 @default.
• W3042133452 cites W2119369921 @default.
• W3042133452 cites W2122468991 @default.
• W3042133452 cites W2123309150 @default.
• W3042133452 cites W2131434738 @default.
• W3042133452 cites W2155121555 @default.
• W3042133452 cites W2168691903 @default.
• W3042133452 cites W2288762895 @default.
• W3042133452 cites W2473535415 @default.
• W3042133452 cites W2496114304 @default.
• W3042133452 cites W2766788476 @default.
• W3042133452 cites W2796533912 @default.
• W3042133452 cites W2861366762 @default.
• W3042133452 cites W2888589263 @default.
• W3042133452 cites W2984574161 @default.
• W3042133452 cites W2987051117 @default.
• W3042133452 cites W4239096779 @default.
• W3042133452 doi "https://doi.org/10.1161/hypertensionaha.120.15323" @default.
• W3042133452 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32654558" @default.
• W3042133452 hasPublicationYear "2020" @default.
• W3042133452 type Work @default.
• W3042133452 sameAs 3042133452 @default.
• W3042133452 citedByCount "15" @default.
• W3042133452 countsByYear W30421334522021 @default.
• W3042133452 countsByYear W30421334522022 @default.
• W3042133452 countsByYear W30421334522023 @default.
• W3042133452 crossrefType "journal-article" @default.
• W3042133452 hasAuthorship W3042133452A5002289527 @default.
• W3042133452 hasAuthorship W3042133452A5004801541 @default.
• W3042133452 hasAuthorship W3042133452A5011468924 @default.
• W3042133452 hasAuthorship W3042133452A5012339002 @default.
• W3042133452 hasAuthorship W3042133452A5024483983 @default.
• W3042133452 hasAuthorship W3042133452A5049648116 @default.
• W3042133452 hasAuthorship W3042133452A5054578676 @default.
• W3042133452 hasAuthorship W3042133452A5059500249 @default.
• W3042133452 hasAuthorship W3042133452A5073951189 @default.
• W3042133452 hasAuthorship W3042133452A5081510830 @default.
• W3042133452 hasAuthorship W3042133452A5089266175 @default.
• W3042133452 hasBestOaLocation W30421334521 @default.
• W3042133452 hasConcept C11783203 @default.
• W3042133452 hasConcept C120665830 @default.
• W3042133452 hasConcept C121332964 @default.
• W3042133452 hasConcept C126322002 @default.
• W3042133452 hasConcept C164705383 @default.
• W3042133452 hasConcept C2776045837 @default.
• W3042133452 hasConcept C2778198053 @default.
• W3042133452 hasConcept C2779134260 @default.
• W3042133452 hasConcept C2908647359 @default.
• W3042133452 hasConcept C44249647 @default.
• W3042133452 hasConcept C500558357 @default.
• W3042133452 hasConcept C61511704 @default.
• W3042133452 hasConcept C71924100 @default.
• W3042133452 hasConcept C78085059 @default.
• W3042133452 hasConcept C82789193 @default.
• W3042133452 hasConcept C99454951 @default.
• W3042133452 hasConceptScore W3042133452C11783203 @default.
• W3042133452 hasConceptScore W3042133452C120665830 @default.
• W3042133452 hasConceptScore W3042133452C121332964 @default.
• W3042133452 hasConceptScore W3042133452C126322002 @default.
• W3042133452 hasConceptScore W3042133452C164705383 @default.
• W3042133452 hasConceptScore W3042133452C2776045837 @default.
• W3042133452 hasConceptScore W3042133452C2778198053 @default.
• W3042133452 hasConceptScore W3042133452C2779134260 @default.
• W3042133452 hasConceptScore W3042133452C2908647359 @default.
• W3042133452 hasConceptScore W3042133452C44249647 @default.
• W3042133452 hasConceptScore W3042133452C500558357 @default.
• W3042133452 hasConceptScore W3042133452C61511704 @default.
• W3042133452 hasConceptScore W3042133452C71924100 @default.
• W3042133452 hasConceptScore W3042133452C78085059 @default.

• next