Matches in SemOpenAlex for { <https://semopenalex.org/work/W3042318085> ?p ?o ?g. }
- W3042318085 abstract "Gliomas are the most common primary brain tumors. Among them, glioblastoma (GBM) possesses the most malignant phenotype. Despite the current standard therapy using an alkylating anticancer agent, temozolomide, most patients with GBM die within 2 years. Novel chemotherapeutic agents are urgently needed to improve the prognosis of GBM. One of the solutions, drug repositioning, which broadens the indications of existing drugs, has gained attention. Herein, we categorize candidate agents, which are newly identified as therapeutic drugs for malignant glioma into 10 classifications based on these original identifications. Some drugs are in clinical trials with hope. Additionally, the obstacles, which should be overcome in order to accomplish drug repositioning as an application for GBM and the future perspectives, have been discussed." @default.
- W3042318085 created "2020-07-23" @default.
- W3042318085 creator A5008290857 @default.
- W3042318085 creator A5022608763 @default.
- W3042318085 creator A5034771136 @default.
- W3042318085 creator A5051703744 @default.
- W3042318085 creator A5057493826 @default.
- W3042318085 date "2020-12-02" @default.
- W3042318085 modified "2023-09-23" @default.
- W3042318085 title "Drug Repositioning for the Treatment of Glioma: Current State and Future Perspective" @default.
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