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- W3042447394 abstract "The sinoatrial node exhibits high amounts of desmin and desmoplakin in structures we call “lateral intercalated disks,” connecting side-by-side adjacent cardiomyocytes. These structures are diminished in desmin-deficient mouse models. Misregulation of T-type Ca 2+ current and hyperpolarization-activated cyclic nucleotide-gated K + channel 1 was proved along with prolonged interatrial conduction and cardiac autonomic nervous system dysfunction." @default.
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- W3042447394 date "2020-09-01" @default.
- W3042447394 modified "2023-10-15" @default.
- W3042447394 title "Desmin is essential for the structure and function of the sinoatrial node: implications for increased arrhythmogenesis" @default.
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- W3042447394 doi "https://doi.org/10.1152/ajpheart.00594.2019" @default.
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