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- W3042466221 endingPage "140869" @default.
- W3042466221 startingPage "140869" @default.
- W3042466221 abstract "Polybrominated diphenyl ethers (PBDEs) are ubiquitous, toxic and persistent pollutants in environments. Microalgae frequent exposed to these pollutants may possess defense mechanisms against their toxicity and have the ability to metabolize them, thus are important in bioremediation. This study investigated the mechanism of a Chlorella isolate to degrade BDE-47, a common PBDE congener, and its subcellular responses to BDE-47 stress. Results showed that 86-98% of the spiked BDE-47 was removed by Chlorella via adsorption, uptake and metabolism. BDE-47 was metabolized through debromination, hydroxylation and methoxylation. The oxidative transformation to hydroxylated products was the initial and main metabolic process. BDE-47 induced the production of hydrogen peroxide (H2O2) in cell wall, plasma membrane and chloroplast of Chlorella, and such increase was regulated by nicotinamide adenine dinucleotide phosphate oxidase and H2O2-producing peroxidases (PODs). The activity of H2O2-consuming PODs and the content of glutathione were also significantly enhanced to detoxify the oxidative stress." @default.
- W3042466221 created "2020-07-23" @default.
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- W3042466221 date "2020-11-01" @default.
- W3042466221 modified "2023-09-24" @default.
- W3042466221 title "Physiological response and oxidative transformation of 2,2′,4,4′-tetrabromodiphenyl ether (BDE-47) by a Chlorella isolate" @default.
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- W3042466221 doi "https://doi.org/10.1016/j.scitotenv.2020.140869" @default.
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