Matches in SemOpenAlex for { <https://semopenalex.org/work/W3042730392> ?p ?o ?g. }
Showing items 1 to 97 of
97
with 100 items per page.
- W3042730392 abstract "Background: Studies on the fractional extracts of Galium verum L. have confirmed their cytotoxicity and anticancer effects on various cancer cell lines. Objectives: The present study aimed to investigate the cytotoxic effects of Galium verum extracts on liver and colon cancer cell lines. Methods: Colon cancer (HT29) and liver (HepG2) cell lines were randomly divided into the test and control groups and exposed to 100, 50, 25, 12.5, 6.25, and 3.125 µg/mL of the extract. MTT assay was used to evaluate the viability of the cells, and the groups were compared in the GraphPad Prism software using Tukey’s post-hoc test. Results: The chloroform fractional extract of Galium verum exerted cytotoxic effects on HT29 at the concentrations of 100 and 50 µg/mL and increased the cell viability of HepG2 cancer cells. On the other hand, the fraction of petroleum ether had cytotoxic effects on HT29 at all the determined concentrations, as well as on HepG2 at the concentration of 3.125 µg/mL. In addition, the treatment of HT29 with various concentrations of the petroleum ether fractional extract and HepG2 treatment with the same extract at the concentration of 3.125 µg/mL significantly decreased cell viability compared to the control group. The IC50 concentration was determined at > 100 µg/mL. Conclusions: According to the results, the fractional extract of petroleum ether had cytotoxic effects on HT29 cancer cells at all the concentrations, while it affected HepG2 cancer cells only at the concentration of 3.125 µg/mL." @default.
- W3042730392 created "2020-07-23" @default.
- W3042730392 creator A5003485480 @default.
- W3042730392 creator A5018900689 @default.
- W3042730392 creator A5026095091 @default.
- W3042730392 creator A5039159903 @default.
- W3042730392 date "2020-07-15" @default.
- W3042730392 modified "2023-09-25" @default.
- W3042730392 title "The Cytotoxicity of the Chloroform and Petroleum Ether Fractional Extracts of Galium verum L. in HepG2 and HT29 Cell Lines" @default.
- W3042730392 cites W1967139428 @default.
- W3042730392 cites W2009570623 @default.
- W3042730392 cites W2035787997 @default.
- W3042730392 cites W2037166773 @default.
- W3042730392 cites W2047160603 @default.
- W3042730392 cites W2068573342 @default.
- W3042730392 cites W2070734420 @default.
- W3042730392 cites W2077896639 @default.
- W3042730392 cites W2139041495 @default.
- W3042730392 cites W2401009689 @default.
- W3042730392 cites W2789935688 @default.
- W3042730392 cites W2792709354 @default.
- W3042730392 cites W2810009250 @default.
- W3042730392 cites W2883916571 @default.
- W3042730392 cites W2906795622 @default.
- W3042730392 cites W2911910338 @default.
- W3042730392 cites W2913384788 @default.
- W3042730392 cites W2969916350 @default.
- W3042730392 cites W2973357643 @default.
- W3042730392 doi "https://doi.org/10.5812/jkums.101079" @default.
- W3042730392 hasPublicationYear "2020" @default.
- W3042730392 type Work @default.
- W3042730392 sameAs 3042730392 @default.
- W3042730392 citedByCount "9" @default.
- W3042730392 countsByYear W30427303922021 @default.
- W3042730392 countsByYear W30427303922022 @default.
- W3042730392 countsByYear W30427303922023 @default.
- W3042730392 crossrefType "journal-article" @default.
- W3042730392 hasAuthorship W3042730392A5003485480 @default.
- W3042730392 hasAuthorship W3042730392A5018900689 @default.
- W3042730392 hasAuthorship W3042730392A5026095091 @default.
- W3042730392 hasAuthorship W3042730392A5039159903 @default.
- W3042730392 hasBestOaLocation W30427303921 @default.
- W3042730392 hasConcept C109316439 @default.
- W3042730392 hasConcept C121608353 @default.
- W3042730392 hasConcept C126322002 @default.
- W3042730392 hasConcept C1491633281 @default.
- W3042730392 hasConcept C154317977 @default.
- W3042730392 hasConcept C185592680 @default.
- W3042730392 hasConcept C202751555 @default.
- W3042730392 hasConcept C2776148806 @default.
- W3042730392 hasConcept C2776231280 @default.
- W3042730392 hasConcept C2780783641 @default.
- W3042730392 hasConcept C2781144210 @default.
- W3042730392 hasConcept C43617362 @default.
- W3042730392 hasConcept C4725764 @default.
- W3042730392 hasConcept C53227056 @default.
- W3042730392 hasConcept C55493867 @default.
- W3042730392 hasConcept C556039675 @default.
- W3042730392 hasConcept C71924100 @default.
- W3042730392 hasConcept C98274493 @default.
- W3042730392 hasConceptScore W3042730392C109316439 @default.
- W3042730392 hasConceptScore W3042730392C121608353 @default.
- W3042730392 hasConceptScore W3042730392C126322002 @default.
- W3042730392 hasConceptScore W3042730392C1491633281 @default.
- W3042730392 hasConceptScore W3042730392C154317977 @default.
- W3042730392 hasConceptScore W3042730392C185592680 @default.
- W3042730392 hasConceptScore W3042730392C202751555 @default.
- W3042730392 hasConceptScore W3042730392C2776148806 @default.
- W3042730392 hasConceptScore W3042730392C2776231280 @default.
- W3042730392 hasConceptScore W3042730392C2780783641 @default.
- W3042730392 hasConceptScore W3042730392C2781144210 @default.
- W3042730392 hasConceptScore W3042730392C43617362 @default.
- W3042730392 hasConceptScore W3042730392C4725764 @default.
- W3042730392 hasConceptScore W3042730392C53227056 @default.
- W3042730392 hasConceptScore W3042730392C55493867 @default.
- W3042730392 hasConceptScore W3042730392C556039675 @default.
- W3042730392 hasConceptScore W3042730392C71924100 @default.
- W3042730392 hasConceptScore W3042730392C98274493 @default.
- W3042730392 hasIssue "2" @default.
- W3042730392 hasLocation W30427303921 @default.
- W3042730392 hasOpenAccess W3042730392 @default.
- W3042730392 hasPrimaryLocation W30427303921 @default.
- W3042730392 hasRelatedWork W1485115657 @default.
- W3042730392 hasRelatedWork W1500704576 @default.
- W3042730392 hasRelatedWork W1973972548 @default.
- W3042730392 hasRelatedWork W1990434843 @default.
- W3042730392 hasRelatedWork W2352468437 @default.
- W3042730392 hasRelatedWork W2395050301 @default.
- W3042730392 hasRelatedWork W2981134861 @default.
- W3042730392 hasRelatedWork W3088450286 @default.
- W3042730392 hasRelatedWork W3189141869 @default.
- W3042730392 hasRelatedWork W1903439640 @default.
- W3042730392 hasVolume "24" @default.
- W3042730392 isParatext "false" @default.
- W3042730392 isRetracted "false" @default.
- W3042730392 magId "3042730392" @default.
- W3042730392 workType "article" @default.