Matches in SemOpenAlex for { <https://semopenalex.org/work/W3042772029> ?p ?o ?g. }
Showing items 1 to 89 of
89
with 100 items per page.
- W3042772029 endingPage "336" @default.
- W3042772029 startingPage "319" @default.
- W3042772029 abstract "Abstract This study aimed to quantitatively compare the difference in protein expression in the progression of pulp pathogenesis, as well as to describe the biological functions of proteins identified in pulp tissue. Samples were obtained from six patients treated at the Araçatuba School of Dentistry and were divided into three groups: normal pulp - from teeth extracted for orthodontic indication; inflamed pulp and necrotic pulp - from patients diagnosed with irreversible pulpitis and chronic apical periodontitis, respectively. After previous proteomic preparation, dental pulp samples were processed for label-free quantitative proteomic analysis in a nanoACQUITY UPLC-Xevo QTof MS system. The difference in expression between the groups was calculated using the Protein Lynx Global Service software using the Monte Carlo algorithm. A total of 465 human proteins were identified in all groups. The most expressed proteins in the inflamed pulp group in relation to the normal pulp group were hemoglobin, peroxiredoxins and immunoglobulins, whereas the less expressed were the tubulins. Expression levels of albumins, immunoglobulins and alpha-2-macroglobulin were higher in the necrotic pulp group than in the inflamed pulp group. As for the qualitative analysis, the most prevalent protein functions in the normal pulp group were metabolic and energetic pathways; in the inflamed pulp group: cellular communication and signal transduction; and regulation and repair of DNA/RNA, while in the necrotic pulp group proteins were associated with the immune response. Thus, proteomic analysis showed quantitative and qualitative differences in protein expression in different types of pulp conditions." @default.
- W3042772029 created "2020-07-23" @default.
- W3042772029 creator A5008233238 @default.
- W3042772029 creator A5015463591 @default.
- W3042772029 creator A5018672924 @default.
- W3042772029 creator A5025698678 @default.
- W3042772029 creator A5054346469 @default.
- W3042772029 creator A5069866987 @default.
- W3042772029 creator A5072401426 @default.
- W3042772029 date "2020-06-01" @default.
- W3042772029 modified "2023-10-12" @default.
- W3042772029 title "Comparative Analysis of the Proteomic Profile of the Dental Pulp in Different Conditions. A Pilot Study" @default.
- W3042772029 cites W1753222877 @default.
- W3042772029 cites W1836273607 @default.
- W3042772029 cites W1971131580 @default.
- W3042772029 cites W1997552453 @default.
- W3042772029 cites W2004018503 @default.
- W3042772029 cites W2046153321 @default.
- W3042772029 cites W2050935157 @default.
- W3042772029 cites W2060740622 @default.
- W3042772029 cites W2062050705 @default.
- W3042772029 cites W2085083913 @default.
- W3042772029 cites W2091911972 @default.
- W3042772029 cites W2099188953 @default.
- W3042772029 cites W2123452260 @default.
- W3042772029 cites W2139856055 @default.
- W3042772029 cites W2144881597 @default.
- W3042772029 cites W2162198764 @default.
- W3042772029 cites W2415373443 @default.
- W3042772029 cites W2594803209 @default.
- W3042772029 cites W2734698022 @default.
- W3042772029 cites W2894612801 @default.
- W3042772029 doi "https://doi.org/10.1590/0103-6440202003167" @default.
- W3042772029 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32667518" @default.
- W3042772029 hasPublicationYear "2020" @default.
- W3042772029 type Work @default.
- W3042772029 sameAs 3042772029 @default.
- W3042772029 citedByCount "7" @default.
- W3042772029 countsByYear W30427720292020 @default.
- W3042772029 countsByYear W30427720292021 @default.
- W3042772029 countsByYear W30427720292022 @default.
- W3042772029 countsByYear W30427720292023 @default.
- W3042772029 crossrefType "journal-article" @default.
- W3042772029 hasAuthorship W3042772029A5008233238 @default.
- W3042772029 hasAuthorship W3042772029A5015463591 @default.
- W3042772029 hasAuthorship W3042772029A5018672924 @default.
- W3042772029 hasAuthorship W3042772029A5025698678 @default.
- W3042772029 hasAuthorship W3042772029A5054346469 @default.
- W3042772029 hasAuthorship W3042772029A5069866987 @default.
- W3042772029 hasAuthorship W3042772029A5072401426 @default.
- W3042772029 hasBestOaLocation W30427720291 @default.
- W3042772029 hasConcept C161312837 @default.
- W3042772029 hasConcept C185592680 @default.
- W3042772029 hasConcept C188442228 @default.
- W3042772029 hasConcept C199343813 @default.
- W3042772029 hasConcept C2779700951 @default.
- W3042772029 hasConcept C71924100 @default.
- W3042772029 hasConcept C86803240 @default.
- W3042772029 hasConceptScore W3042772029C161312837 @default.
- W3042772029 hasConceptScore W3042772029C185592680 @default.
- W3042772029 hasConceptScore W3042772029C188442228 @default.
- W3042772029 hasConceptScore W3042772029C199343813 @default.
- W3042772029 hasConceptScore W3042772029C2779700951 @default.
- W3042772029 hasConceptScore W3042772029C71924100 @default.
- W3042772029 hasConceptScore W3042772029C86803240 @default.
- W3042772029 hasIssue "3" @default.
- W3042772029 hasLocation W30427720291 @default.
- W3042772029 hasLocation W30427720292 @default.
- W3042772029 hasLocation W30427720293 @default.
- W3042772029 hasLocation W30427720294 @default.
- W3042772029 hasOpenAccess W3042772029 @default.
- W3042772029 hasPrimaryLocation W30427720291 @default.
- W3042772029 hasRelatedWork W1958115281 @default.
- W3042772029 hasRelatedWork W2059654184 @default.
- W3042772029 hasRelatedWork W2101756000 @default.
- W3042772029 hasRelatedWork W2104422287 @default.
- W3042772029 hasRelatedWork W2521374942 @default.
- W3042772029 hasRelatedWork W2744279281 @default.
- W3042772029 hasRelatedWork W3022119848 @default.
- W3042772029 hasRelatedWork W3080913025 @default.
- W3042772029 hasRelatedWork W4298122859 @default.
- W3042772029 hasRelatedWork W4308924600 @default.
- W3042772029 hasVolume "31" @default.
- W3042772029 isParatext "false" @default.
- W3042772029 isRetracted "false" @default.
- W3042772029 magId "3042772029" @default.
- W3042772029 workType "article" @default.