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- W3042781144 abstract "Purpose : Myopia is typically characterised by increased axial lengthand develops during childhood. Excessive or intense near work may be associatedwith myopia development and progression, and ocular changes during accommodationhave been proposed as a possible mechanism. Small increases in axial lengthduring accommodation have been demonstrated in adults, however these changeshave not been examined in children, nor at high accommodation demands. Methods : Ocular biometry of the left eye was measured in 91 children(mean age: 8.3 ± 1.8 years) with a range of refractive errors (mean sphericalequivalent: +0.51 ± 0.64 D), using a non-contact optical biometer (ZeissIOLMaster 700) at four accommodation demands (0, 3, 6 and 9 D). Evidence of reliablebiometry measures and anterior segment accommodative responses were observed ateach demand for 49 participants who were included in the analysis. The averagecentral corneal thickness (CCT), anterior chamber depth (ACD), lens thickness(LT), anterior segment length (ASL), vitreous chamber depth (VCD) and axiallength (AL) were calculated at each accommodation demand. AL and VCD were also“corrected” to account for increased LT during accommodation (cAL and cVCD). Results : AL and cAL increased monotonically with increasing accommodationdemand (p < 0.0001). The increase in cAL from 0 D was 5.4 ± 11.4 µm, 9.1 ±10.0 µm and 17.4 ± 13.1 µm(mean ± standard deviation) at 3, 6 and 9 D, respectively (Figure 1). All otherparameters, apart from CCT, changed significantly with accommodation. LT andASL increased and ACD, VCD and cVCD decreased significantly with increasing accommodationdemand (all p < 0.0001). Conclusions : This study demonstrates that AL increases significantly withincreasing levels of accommodation in children, the magnitude of which appears comparableto that reported in adults up to a 6 D demand. This study is also the first toexamine changes in AL at an accommodation demand of 9 D and demonstrates increasingaxial elongation with high levels of accommodation that children may experienceduring some near tasks. Further studies examining changes in ocular biometrywith prolonged accommodation in children are required to examine a possiblelink with longer term myopia development." @default.
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- W3042781144 date "2019-07-22" @default.
- W3042781144 modified "2023-09-27" @default.
- W3042781144 title "Short-term changes in ocular biometry during accommodation in children" @default.
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