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• W304295703 abstract "Ocular inflammation is a significant cause of ocular morbidity and visual impairment. Topical, periocular, intraocular, and systemic corticosteroids are highly effective for treating appropriate forms of ocular inflammation. However, their use may be constrained by local and/or systemic side effects, especially if long-term therapy is required. As a result, immunosuppressive agents increasingly have been used to manage ocular inflammation alongside or in place of corticosteroids. The four categories of agents used today are antimetabolites [primarily methotrexate, mycophenolate mofetil (MMF), and azathioprine]; T-cell inhibitors (usually cyclosporine, less often tacrolimus or sirolimus); alkylating agents (cyclophosphamide and chlorambucil); and biologic agents [tumor necrosis factor (TNF) inhibitors, lymphocyte inhibitors, and interleukin inhibitors]. The primary goals of immunosuppressive therapy are (1) to control inflammation when corticosteroids fail to do so; (2) to prevent corticosteroid-induced toxicity when the necessary corticosteroid dosage exceeds the desired or safe level (corticosteroid sparing); and (3) to treat specific high-risk uveitis syndromes known to respond poorly to corticosteroids alone. Growing evidence shows the effectiveness of immunosuppressive drugs in achieving these goals, as well as improved visual function, prevention of ocular complications, and in some cases even disease remission. However, these agents also have side effects, which must be considered in each patient's management. In this report, we summarize the effectiveness and safety of immunosuppressive drug therapy utilized in the treatment of ocular inflammatory diseases." @default.
• W304295703 created "2016-06-24" @default.
• W304295703 creator A5062196360 @default.
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• W304295703 date "2015-12-01" @default.
• W304295703 modified "2023-09-25" @default.
• W304295703 title "Immunosuppressive therapy for eye diseases: Effectiveness, safety, side effects and their prevention" @default.
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• W304295703 cites W1789451169 @default.
• W304295703 cites W1965202208 @default.
• W304295703 cites W1966524332 @default.
• W304295703 cites W1967235326 @default.
• W304295703 cites W1968166575 @default.
• W304295703 cites W1968434914 @default.
• W304295703 cites W1972298566 @default.
• W304295703 cites W1973387000 @default.
• W304295703 cites W1974162532 @default.
• W304295703 cites W1975736815 @default.
• W304295703 cites W1984387425 @default.
• W304295703 cites W1984702041 @default.
• W304295703 cites W2000547681 @default.
• W304295703 cites W2001019387 @default.
• W304295703 cites W2004670542 @default.
• W304295703 cites W2009663265 @default.
• W304295703 cites W2014968919 @default.
• W304295703 cites W2017281030 @default.
• W304295703 cites W2024644107 @default.
• W304295703 cites W2026992146 @default.
• W304295703 cites W2027090790 @default.
• W304295703 cites W2028672514 @default.
• W304295703 cites W2030259354 @default.
• W304295703 cites W2035244366 @default.
• W304295703 cites W2040235283 @default.
• W304295703 cites W2042020224 @default.
• W304295703 cites W2045952946 @default.
• W304295703 cites W2052038595 @default.
• W304295703 cites W2055913604 @default.
• W304295703 cites W2056756250 @default.
• W304295703 cites W2058660748 @default.
• W304295703 cites W2059080840 @default.
• W304295703 cites W2061198727 @default.
• W304295703 cites W2065541718 @default.
• W304295703 cites W2075580710 @default.
• W304295703 cites W2077279908 @default.
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• W304295703 cites W4230996310 @default.
• W304295703 cites W4238101131 @default.
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• W304295703 doi "https://doi.org/10.1016/j.tjo.2015.03.004" @default.
• W304295703 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5602133" @default.
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