Matches in SemOpenAlex for { <https://semopenalex.org/work/W3042977881> ?p ?o ?g. }
- W3042977881 endingPage "222" @default.
- W3042977881 startingPage "203" @default.
- W3042977881 abstract "Background:Central vision loss, such as in the case of age-related macular degeneration (AMD), has a a major negative impact on patients’ quality of life. However, some patients have shown spontaneous adaptive strategies development, mostly relying on their peripheral vision. Objective:This study a ssesses eye movement and eccentric visual function adaptive behaviors of a healthy population in the presence of simulated central vision loss. We wished to determine how central vision loss affects eye movements, specifically the foveal-target alignment. Methods:Fifteen healthy participants (7 females, M = 21.69, SD = 2.13) discriminated the orientation of a Gabor relative to the vertical located at 12 deg of eccentricity to the right of fixation, in the presence of a gaze-contingent artificial central scotoma either visible or invisible. The artificial central scotoma was 4° diameter in order to simulate an earlier stage of degenerative disease while still impairing foveal vision. The target’s orientation varied between 10° counter-clockwise and 10° clockwise. Each participant performed four blocks of 75 trials each per day over 10 days, the first day being a baseline without scotoma. Results:We found changes in the endpoints of the 1st saccade over the practice days. The most common pattern was a gradual upward shift. We also observed a significant increase in discrimination performance over the 9 days of practice. We did not find any difference linked to the scotoma types. Conclusions:These findings suggest that the presence of an artificial central scotoma combined with a challenging discrimination task induces both changes in saccade planning mechanisms, resulting in a new eccentric-target alignment, and improvements in eccentric visual functions. This demonstrates the potential of this research paradigm to understand and potentially improve visual function in patients with central vision loss." @default.
- W3042977881 created "2020-07-23" @default.
- W3042977881 creator A5002132364 @default.
- W3042977881 creator A5037808237 @default.
- W3042977881 creator A5040793305 @default.
- W3042977881 creator A5044256076 @default.
- W3042977881 creator A5073768567 @default.
- W3042977881 creator A5089831005 @default.
- W3042977881 date "2020-08-20" @default.
- W3042977881 modified "2023-10-17" @default.
- W3042977881 title "Changes in eye movement parameters in the presence of an artificial central scotoma" @default.
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