FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3043132260> ?p ?o ?g. }

• W3043132260 endingPage "e1008670" @default.
• W3043132260 startingPage "e1008670" @default.
• W3043132260 abstract "Increasing evidence suggests important roles for long noncoding RNAs (lncRNAs) as new gene modulators involved in various biological processes. However, the function roles of lncRNAs in lower vertebrates are still unknown. Here, we firstly identify a lncRNA, named MAVS antiviral-related lncRNA (MARL), as a key regulator for antiviral immunity in teleost fish. The results indicate that fish MAVS play essential roles in host antiviral responses and inhibition of Siniperca chuatsi rhabdovirus (SCRV) replication. miR-122 reduces MAVS expression and suppress MAVS-mediated antiviral responses, which may help viruses evade host antiviral responses. Further, MARL functions as a competing endogenous RNA (ceRNA) for miR-122 to control protein abundance of MAVS, thereby inhibiting SCRV replication and promoting antiviral responses. Our data not only shed new light on understanding the function role of lncRNA in biological processes in lower vertebrates, but confirmed the hypothesis that ceRNA regulatory networks exist widely in vertebrates." @default.
• W3043132260 created "2020-07-23" @default.
• W3043132260 creator A5017826971 @default.
• W3043132260 creator A5018931275 @default.
• W3043132260 creator A5049947413 @default.
• W3043132260 creator A5077170267 @default.
• W3043132260 creator A5083446090 @default.
• W3043132260 date "2020-07-17" @default.
• W3043132260 modified "2023-10-11" @default.
• W3043132260 title "Long noncoding RNA MARL regulates antiviral responses through suppression miR-122-dependent MAVS downregulation in lower vertebrates" @default.
• W3043132260 cites W1539551850 @default.
• W3043132260 cites W1790919501 @default.
• W3043132260 cites W1839058138 @default.
• W3043132260 cites W1958284284 @default.
• W3043132260 cites W1967517087 @default.
• W3043132260 cites W1970154782 @default.
• W3043132260 cites W1973405995 @default.
• W3043132260 cites W1974115318 @default.
• W3043132260 cites W1976930568 @default.
• W3043132260 cites W1994527775 @default.
• W3043132260 cites W2002706411 @default.
• W3043132260 cites W2003410926 @default.
• W3043132260 cites W2003983029 @default.
• W3043132260 cites W2004714113 @default.
• W3043132260 cites W2006556963 @default.
• W3043132260 cites W2017784906 @default.
• W3043132260 cites W2034412957 @default.
• W3043132260 cites W2044330780 @default.
• W3043132260 cites W2048194168 @default.
• W3043132260 cites W2048552348 @default.
• W3043132260 cites W2055545565 @default.
• W3043132260 cites W2061548680 @default.
• W3043132260 cites W2064024180 @default.
• W3043132260 cites W2075320162 @default.
• W3043132260 cites W2075596070 @default.
• W3043132260 cites W2093579074 @default.
• W3043132260 cites W2096465161 @default.
• W3043132260 cites W2107277218 @default.
• W3043132260 cites W2107513655 @default.
• W3043132260 cites W2113209482 @default.
• W3043132260 cites W2118317431 @default.
• W3043132260 cites W2133613657 @default.
• W3043132260 cites W2135695964 @default.
• W3043132260 cites W2141885858 @default.
• W3043132260 cites W2144787399 @default.
• W3043132260 cites W2145931730 @default.
• W3043132260 cites W2151922790 @default.
• W3043132260 cites W2152894234 @default.
• W3043132260 cites W2152985701 @default.
• W3043132260 cites W2158541290 @default.
• W3043132260 cites W2161483818 @default.
• W3043132260 cites W2192080449 @default.
• W3043132260 cites W2291209950 @default.
• W3043132260 cites W2347066154 @default.
• W3043132260 cites W2429771129 @default.
• W3043132260 cites W2765693894 @default.
• W3043132260 cites W2811388126 @default.
• W3043132260 cites W2903566006 @default.
• W3043132260 cites W2974507761 @default.
• W3043132260 cites W331284098 @default.
• W3043132260 cites W4320301318 @default.
• W3043132260 doi "https://doi.org/10.1371/journal.ppat.1008670" @default.
• W3043132260 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7390449" @default.
• W3043132260 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32678830" @default.
• W3043132260 hasPublicationYear "2020" @default.
• W3043132260 type Work @default.
• W3043132260 sameAs 3043132260 @default.
• W3043132260 citedByCount "58" @default.
• W3043132260 countsByYear W30431322602021 @default.
• W3043132260 countsByYear W30431322602022 @default.
• W3043132260 countsByYear W30431322602023 @default.
• W3043132260 crossrefType "journal-article" @default.
• W3043132260 hasAuthorship W3043132260A5017826971 @default.
• W3043132260 hasAuthorship W3043132260A5018931275 @default.
• W3043132260 hasAuthorship W3043132260A5049947413 @default.
• W3043132260 hasAuthorship W3043132260A5077170267 @default.
• W3043132260 hasAuthorship W3043132260A5083446090 @default.
• W3043132260 hasBestOaLocation W30431322601 @default.
• W3043132260 hasConcept C104317684 @default.
• W3043132260 hasConcept C127561419 @default.
• W3043132260 hasConcept C14036430 @default.
• W3043132260 hasConcept C140704245 @default.
• W3043132260 hasConcept C145059251 @default.
• W3043132260 hasConcept C2522874641 @default.
• W3043132260 hasConcept C54355233 @default.
• W3043132260 hasConcept C60365752 @default.
• W3043132260 hasConcept C62203573 @default.
• W3043132260 hasConcept C67705224 @default.
• W3043132260 hasConcept C6929976 @default.
• W3043132260 hasConcept C70721500 @default.
• W3043132260 hasConcept C86803240 @default.
• W3043132260 hasConcept C95444343 @default.
• W3043132260 hasConceptScore W3043132260C104317684 @default.
• W3043132260 hasConceptScore W3043132260C127561419 @default.
• W3043132260 hasConceptScore W3043132260C14036430 @default.
• W3043132260 hasConceptScore W3043132260C140704245 @default.
• W3043132260 hasConceptScore W3043132260C145059251 @default.
• W3043132260 hasConceptScore W3043132260C2522874641 @default.

• next