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- W3043137219 endingPage "396" @default.
- W3043137219 startingPage "389" @default.
- W3043137219 abstract "Abstract: Sulfur dioxide (SO 2 ) was previously known as a harmful gas in air pollution. Recently, it was reported that SO 2 can be endogenously generated in cardiovascular tissues. Many studies have revealed that endogenous SO 2 has important physiological and pathophysiological significance and pharmacological potential. As a novel gasotransmitter, SO 2 has important regulatory effects on the heart. It has a dose-dependent negative inotropic effect on cardiac function, in which L-type calcium channels are involved. SO 2 can also attenuate myocardial injury caused by various harmful stimuli and play an important role in myocardial ischemia-reperfusion injury and myocardial hypertrophy. These effects are thought to be linked to its ability to reduce inflammation and as an antioxidant. In addition, SO 2 regulates cardiomyocyte apoptosis and autophagy. Therefore, endogenous SO 2 plays an important role in maintaining cardiovascular system homeostasis. In the present review, the literature concerning the metabolism of endogenous SO 2 , its cardiac toxicological effects and physiological regulatory effects, mechanisms for SO 2 -mediated myocardial protection and its pharmacological applications are summarized and discussed." @default.
- W3043137219 created "2020-07-23" @default.
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- W3043137219 creator A5085140875 @default.
- W3043137219 date "2020-10-01" @default.
- W3043137219 modified "2023-09-25" @default.
- W3043137219 title "Sulfur Dioxide: An Endogenous Protector Against Myocardial Injury" @default.
- W3043137219 cites W1195621313 @default.
- W3043137219 cites W1579851397 @default.
- W3043137219 cites W1592150753 @default.
- W3043137219 cites W1789149097 @default.
- W3043137219 cites W1931984034 @default.
- W3043137219 cites W1978244620 @default.
- W3043137219 cites W1979831403 @default.
- W3043137219 cites W1981794140 @default.
- W3043137219 cites W1984741878 @default.
- W3043137219 cites W1984834899 @default.
- W3043137219 cites W1993245757 @default.
- W3043137219 cites W1995024997 @default.
- W3043137219 cites W2000205368 @default.
- W3043137219 cites W2000954596 @default.
- W3043137219 cites W2002583208 @default.
- W3043137219 cites W2005587402 @default.
- W3043137219 cites W2007011272 @default.
- W3043137219 cites W2010179394 @default.
- W3043137219 cites W2011256637 @default.
- W3043137219 cites W2011741149 @default.
- W3043137219 cites W2012521615 @default.
- W3043137219 cites W2015593138 @default.
- W3043137219 cites W2023225298 @default.
- W3043137219 cites W2033781762 @default.
- W3043137219 cites W2033813290 @default.
- W3043137219 cites W2037325584 @default.
- W3043137219 cites W2051085581 @default.
- W3043137219 cites W2061598582 @default.
- W3043137219 cites W2062526619 @default.
- W3043137219 cites W2063129749 @default.
- W3043137219 cites W2063420743 @default.
- W3043137219 cites W2070150463 @default.
- W3043137219 cites W2071475119 @default.
- W3043137219 cites W2083137267 @default.
- W3043137219 cites W2083367374 @default.
- W3043137219 cites W2090454487 @default.
- W3043137219 cites W2097744068 @default.
- W3043137219 cites W2111542355 @default.
- W3043137219 cites W2119037313 @default.
- W3043137219 cites W2124343538 @default.
- W3043137219 cites W2125680105 @default.
- W3043137219 cites W2127744036 @default.
- W3043137219 cites W2133291887 @default.
- W3043137219 cites W2140154908 @default.
- W3043137219 cites W2148834317 @default.
- W3043137219 cites W2150737177 @default.
- W3043137219 cites W2151908732 @default.
- W3043137219 cites W2157493434 @default.
- W3043137219 cites W2168030124 @default.
- W3043137219 cites W2170015173 @default.
- W3043137219 cites W2171160325 @default.
- W3043137219 cites W2179358839 @default.
- W3043137219 cites W2319556003 @default.
- W3043137219 cites W2412592589 @default.
- W3043137219 cites W2471207043 @default.
- W3043137219 cites W2524668878 @default.
- W3043137219 cites W2579916268 @default.
- W3043137219 cites W2593505831 @default.
- W3043137219 cites W2606522938 @default.
- W3043137219 cites W2613469768 @default.
- W3043137219 cites W2733828617 @default.
- W3043137219 cites W2735527928 @default.
- W3043137219 cites W2763611756 @default.
- W3043137219 cites W2767174919 @default.
- W3043137219 cites W2767604253 @default.
- W3043137219 cites W2772539661 @default.
- W3043137219 cites W2778850542 @default.
- W3043137219 cites W2799410199 @default.
- W3043137219 cites W2801150533 @default.
- W3043137219 cites W2803997671 @default.
- W3043137219 cites W2810943803 @default.
- W3043137219 cites W2890380206 @default.
- W3043137219 cites W2893942412 @default.
- W3043137219 cites W2901470541 @default.
- W3043137219 cites W2911859966 @default.
- W3043137219 cites W2922282831 @default.
- W3043137219 cites W2923860976 @default.
- W3043137219 cites W2958947951 @default.
- W3043137219 cites W2959156367 @default.
- W3043137219 cites W39489114 @default.
- W3043137219 cites W4234467251 @default.
- W3043137219 doi "https://doi.org/10.1097/fjc.0000000000000882" @default.
- W3043137219 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32675748" @default.
- W3043137219 hasPublicationYear "2020" @default.
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