FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3043174910> ?p ?o ?g. }

• W3043174910 abstract "Abstract PCR methods are presently the standard for the diagnosis of Coronavirus disease 2019 (COVID-19), but additional methodologies are needed to complement PCR methods, which have some limitations. Here, we validated and investigated the usefulness of measuring serum antibodies against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) using the iFlash3000 CLIA analyzer. We measured IgM and IgG titers against SARS-CoV-2 in sera collected from 26 PCR-positive COVID-19 patients, 53 COVID-19-suspected but PCR-negative patients, and 20 and 100 randomly selected non-COVID-19 patients who visited our hospital in 2020 and 2017, respectively. The within-day and between-day precisions were regarded as good, since the coefficient variations were below 5%. Linearity was also considered good between 0.6 AU/mL and 112.7 AU/mL for SARS-CoV-2 IgM and between 3.2 AU/mL and 55.3 AU/mL for SARS-CoV-2 IgG, while the linearity curves plateaued above the upper measurement range. We also confirmed that the seroconversion and no-antibody titers were over the cutoff values in all 100 serum samples collected in 2017. These results indicate that this measurement system successfully detects SARS-CoV-2 IgM/IgG. We observed four false-positive cases in the IgM assay and no false-positive cases in the IgG assay when 111 serum samples known to contain autoantibodies were evaluated. The concordance rates of the antibody test with the PCR test were 98.1% for SARS-CoV-2 IgM and 100% for IgG among PCR-negative cases and 30.8% for SARS-CoV-2 IgM and 73.1% for SARS-CoV-2 IgG among PCR-positive cases. In conclusion, the performance of this measurement system is sufficient for use in laboratory testing." @default.
• W3043174910 created "2020-07-23" @default.
• W3043174910 creator A5000561426 @default.
• W3043174910 creator A5011604586 @default.
• W3043174910 creator A5014010927 @default.
• W3043174910 creator A5014464078 @default.
• W3043174910 creator A5020979556 @default.
• W3043174910 creator A5024321967 @default.
• W3043174910 creator A5025499666 @default.
• W3043174910 creator A5034686522 @default.
• W3043174910 creator A5037541292 @default.
• W3043174910 creator A5048379128 @default.
• W3043174910 creator A5050708809 @default.
• W3043174910 creator A5052431185 @default.
• W3043174910 creator A5059263459 @default.
• W3043174910 creator A5060462446 @default.
• W3043174910 creator A5077332068 @default.
• W3043174910 creator A5091537787 @default.
• W3043174910 date "2020-07-18" @default.
• W3043174910 modified "2023-09-30" @default.
• W3043174910 title "Validation of a new automated chemiluminescent anti-SARS-CoV-2 IgM and IgG antibody assay system detecting both N and S proteins in Japan" @default.
• W3043174910 cites W1991552092 @default.
• W3043174910 cites W2306794997 @default.
• W3043174910 cites W3001118548 @default.
• W3043174910 cites W3001897055 @default.
• W3043174910 cites W3003668884 @default.
• W3043174910 cites W3004318991 @default.
• W3043174910 cites W3005827208 @default.
• W3043174910 cites W3007104924 @default.
• W3043174910 cites W3008827533 @default.
• W3043174910 cites W3012923834 @default.
• W3043174910 cites W3013213522 @default.
• W3043174910 cites W3013893137 @default.
• W3043174910 cites W3013930084 @default.
• W3043174910 cites W3014682585 @default.
• W3043174910 cites W3016000491 @default.
• W3043174910 cites W3016165935 @default.
• W3043174910 cites W3017023889 @default.
• W3043174910 cites W3018826294 @default.
• W3043174910 cites W3025820218 @default.
• W3043174910 cites W3026059552 @default.
• W3043174910 cites W3032138494 @default.
• W3043174910 cites W3165656738 @default.
• W3043174910 doi "https://doi.org/10.1101/2020.07.16.20155796" @default.
• W3043174910 hasPublicationYear "2020" @default.
• W3043174910 type Work @default.
• W3043174910 sameAs 3043174910 @default.
• W3043174910 citedByCount "2" @default.
• W3043174910 countsByYear W30431749102021 @default.
• W3043174910 countsByYear W30431749102022 @default.
• W3043174910 crossrefType "posted-content" @default.
• W3043174910 hasAuthorship W3043174910A5000561426 @default.
• W3043174910 hasAuthorship W3043174910A5011604586 @default.
• W3043174910 hasAuthorship W3043174910A5014010927 @default.
• W3043174910 hasAuthorship W3043174910A5014464078 @default.
• W3043174910 hasAuthorship W3043174910A5020979556 @default.
• W3043174910 hasAuthorship W3043174910A5024321967 @default.
• W3043174910 hasAuthorship W3043174910A5025499666 @default.
• W3043174910 hasAuthorship W3043174910A5034686522 @default.
• W3043174910 hasAuthorship W3043174910A5037541292 @default.
• W3043174910 hasAuthorship W3043174910A5048379128 @default.
• W3043174910 hasAuthorship W3043174910A5050708809 @default.
• W3043174910 hasAuthorship W3043174910A5052431185 @default.
• W3043174910 hasAuthorship W3043174910A5059263459 @default.
• W3043174910 hasAuthorship W3043174910A5060462446 @default.
• W3043174910 hasAuthorship W3043174910A5077332068 @default.
• W3043174910 hasAuthorship W3043174910A5091537787 @default.
• W3043174910 hasBestOaLocation W30431749101 @default.
• W3043174910 hasConcept C126322002 @default.
• W3043174910 hasConcept C145802702 @default.
• W3043174910 hasConcept C159047783 @default.
• W3043174910 hasConcept C159654299 @default.
• W3043174910 hasConcept C160798450 @default.
• W3043174910 hasConcept C163764329 @default.
• W3043174910 hasConcept C185592680 @default.
• W3043174910 hasConcept C203014093 @default.
• W3043174910 hasConcept C2776553844 @default.
• W3043174910 hasConcept C2777451964 @default.
• W3043174910 hasConcept C2779134260 @default.
• W3043174910 hasConcept C2780420688 @default.
• W3043174910 hasConcept C2780898057 @default.
• W3043174910 hasConcept C2994453816 @default.
• W3043174910 hasConcept C3007834351 @default.
• W3043174910 hasConcept C3008058167 @default.
• W3043174910 hasConcept C32611913 @default.
• W3043174910 hasConcept C43617362 @default.
• W3043174910 hasConcept C524204448 @default.
• W3043174910 hasConcept C71924100 @default.
• W3043174910 hasConceptScore W3043174910C126322002 @default.
• W3043174910 hasConceptScore W3043174910C145802702 @default.
• W3043174910 hasConceptScore W3043174910C159047783 @default.
• W3043174910 hasConceptScore W3043174910C159654299 @default.
• W3043174910 hasConceptScore W3043174910C160798450 @default.
• W3043174910 hasConceptScore W3043174910C163764329 @default.
• W3043174910 hasConceptScore W3043174910C185592680 @default.
• W3043174910 hasConceptScore W3043174910C203014093 @default.
• W3043174910 hasConceptScore W3043174910C2776553844 @default.
• W3043174910 hasConceptScore W3043174910C2777451964 @default.
• W3043174910 hasConceptScore W3043174910C2779134260 @default.
• W3043174910 hasConceptScore W3043174910C2780420688 @default.

• next