Matches in SemOpenAlex for { <https://semopenalex.org/work/W3043212844> ?p ?o ?g. }
- W3043212844 endingPage "118103" @default.
- W3043212844 startingPage "118103" @default.
- W3043212844 abstract "Irritable bowel syndrome (IBS) is a chronic functional gastrointestinal (GI) disorder with negative impacts on quality of life of patients. Although the etiology of the disease is still unclear, there are a set of mechanisms and factors involved in IBS pathogenesis. Visceral hypersensitivity, impaired gut barrier, along with minor inflammation and oxidative stress are the most important triggers for IBS induction. Activation of peroxisome proliferator activated receptor-γ (PPAR-γ) has been shown to improve gut barrier, downregulate pro-inflammatory cytokines, reduce free radical production through antioxidative mechanisms, and exert anti-nociceptive effects against somatic pain. An electronic search in PubMed, Google Scholar, Scopus, and Cochrane library was performed and relevant clinical, in vivo and in vitro articles published between 2004 and June 2020 were collected. Search terms included “Irritable Bowel Syndrome” OR “IBS” OR “visceral hypersensitivity” OR “motility dysfunction” AND “peroxisome proliferator activated receptors” OR “PPAR”. Herein, the efficacy of PPARγ signaling as a potential target for IBS treatment is reviewed." @default.
- W3043212844 created "2020-07-23" @default.
- W3043212844 creator A5025708210 @default.
- W3043212844 creator A5036163332 @default.
- W3043212844 creator A5037587111 @default.
- W3043212844 creator A5051926127 @default.
- W3043212844 creator A5055073750 @default.
- W3043212844 creator A5056778982 @default.
- W3043212844 creator A5084340806 @default.
- W3043212844 date "2020-09-01" @default.
- W3043212844 modified "2023-10-18" @default.
- W3043212844 title "PPARγ: A turning point for irritable bowel syndrome treatment" @default.
- W3043212844 cites W1486185235 @default.
- W3043212844 cites W1548860972 @default.
- W3043212844 cites W1593677402 @default.
- W3043212844 cites W1647126819 @default.
- W3043212844 cites W1756692753 @default.
- W3043212844 cites W1967319082 @default.
- W3043212844 cites W1993745956 @default.
- W3043212844 cites W1997648536 @default.
- W3043212844 cites W1999225509 @default.
- W3043212844 cites W1999513011 @default.
- W3043212844 cites W1999794762 @default.
- W3043212844 cites W2012736960 @default.
- W3043212844 cites W2014425464 @default.
- W3043212844 cites W2017435559 @default.
- W3043212844 cites W2018661831 @default.
- W3043212844 cites W2020098107 @default.
- W3043212844 cites W2023584200 @default.
- W3043212844 cites W2026661267 @default.
- W3043212844 cites W2032377531 @default.
- W3043212844 cites W2056707130 @default.
- W3043212844 cites W2057099241 @default.
- W3043212844 cites W2063324581 @default.
- W3043212844 cites W2067414455 @default.
- W3043212844 cites W2073534342 @default.
- W3043212844 cites W2073852177 @default.
- W3043212844 cites W2074762600 @default.
- W3043212844 cites W2075944018 @default.
- W3043212844 cites W2080290298 @default.
- W3043212844 cites W2085843498 @default.
- W3043212844 cites W2089666748 @default.
- W3043212844 cites W2099164108 @default.
- W3043212844 cites W2107869127 @default.
- W3043212844 cites W2113328569 @default.
- W3043212844 cites W2115090185 @default.
- W3043212844 cites W212251127 @default.
- W3043212844 cites W2128211963 @default.
- W3043212844 cites W2130067522 @default.
- W3043212844 cites W2131490500 @default.
- W3043212844 cites W2136054045 @default.
- W3043212844 cites W2137688604 @default.
- W3043212844 cites W2138976301 @default.
- W3043212844 cites W2141136779 @default.
- W3043212844 cites W2149411404 @default.
- W3043212844 cites W2160102993 @default.
- W3043212844 cites W2166849813 @default.
- W3043212844 cites W2174423712 @default.
- W3043212844 cites W2203163745 @default.
- W3043212844 cites W2406650501 @default.
- W3043212844 cites W2508360554 @default.
- W3043212844 cites W2509180035 @default.
- W3043212844 cites W2515727339 @default.
- W3043212844 cites W2588316582 @default.
- W3043212844 cites W2618865740 @default.
- W3043212844 cites W2624674854 @default.
- W3043212844 cites W2748954699 @default.
- W3043212844 cites W2757854799 @default.
- W3043212844 cites W2772599266 @default.
- W3043212844 cites W2797958005 @default.
- W3043212844 cites W2800708724 @default.
- W3043212844 cites W2801215756 @default.
- W3043212844 cites W2885138999 @default.
- W3043212844 cites W2899412681 @default.
- W3043212844 cites W2900896363 @default.
- W3043212844 cites W2901951253 @default.
- W3043212844 cites W2903988569 @default.
- W3043212844 cites W2906801816 @default.
- W3043212844 cites W2909181645 @default.
- W3043212844 cites W2912653988 @default.
- W3043212844 cites W2921817401 @default.
- W3043212844 cites W2927807503 @default.
- W3043212844 cites W2945060101 @default.
- W3043212844 cites W2976495952 @default.
- W3043212844 cites W3012143772 @default.
- W3043212844 cites W3016338294 @default.
- W3043212844 cites W4236897356 @default.
- W3043212844 doi "https://doi.org/10.1016/j.lfs.2020.118103" @default.
- W3043212844 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32681913" @default.
- W3043212844 hasPublicationYear "2020" @default.
- W3043212844 type Work @default.
- W3043212844 sameAs 3043212844 @default.
- W3043212844 citedByCount "8" @default.
- W3043212844 countsByYear W30432128442021 @default.
- W3043212844 countsByYear W30432128442022 @default.
- W3043212844 countsByYear W30432128442023 @default.
- W3043212844 crossrefType "journal-article" @default.
- W3043212844 hasAuthorship W3043212844A5025708210 @default.