Matches in SemOpenAlex for { <https://semopenalex.org/work/W3043237919> ?p ?o ?g. }
- W3043237919 endingPage "144952" @default.
- W3043237919 startingPage "144952" @default.
- W3043237919 abstract "Diabetic nephropathy (DN) as one of the most frequent microvascular complications of diabetic patients causes chronic renal failure and end-stage renal disease. Noncoding RNAs including circular RNAs (circRNAs) and micro RNAs (miRNAs) were widely reported to play a critical role in numerous human diseases including DN. This research was designed to investigate the role of circ_0000064 in diabetic nephropathy progression. The results showed that circ_0000064 significantly promoted mesangial cells proliferation and aggravated fibrosis in DN. In the subsequent mechanism investigation, we found that circ_0000064 was involved in this process by targeting micro RNA miR-143. The inhibition of miR-143 significantly reverses the effect of circ_0000064 silencing on DN. In conclusion, we demonstrated the regulatory role of circ_0000064 in DN and clarified that circ_0000064 play a role in DN via targeting miR-143. Circ_0000064 and miR-143 also showed the potential as a biomarker for DN." @default.
- W3043237919 created "2020-07-23" @default.
- W3043237919 creator A5031524039 @default.
- W3043237919 creator A5039077688 @default.
- W3043237919 creator A5052026299 @default.
- W3043237919 creator A5060741407 @default.
- W3043237919 creator A5061272605 @default.
- W3043237919 creator A5061853276 @default.
- W3043237919 creator A5062755510 @default.
- W3043237919 creator A5072182447 @default.
- W3043237919 date "2020-10-01" @default.
- W3043237919 modified "2023-10-16" @default.
- W3043237919 title "Circular RNA Circ_0000064 promotes the proliferation and fibrosis of mesangial cells via miR-143 in diabetic nephropathy" @default.
- W3043237919 cites W1492748176 @default.
- W3043237919 cites W1970121668 @default.
- W3043237919 cites W1972989638 @default.
- W3043237919 cites W2030166934 @default.
- W3043237919 cites W2030527067 @default.
- W3043237919 cites W2058835062 @default.
- W3043237919 cites W2064165694 @default.
- W3043237919 cites W2082644193 @default.
- W3043237919 cites W2109936378 @default.
- W3043237919 cites W2166196657 @default.
- W3043237919 cites W2285247593 @default.
- W3043237919 cites W2316171452 @default.
- W3043237919 cites W2328453756 @default.
- W3043237919 cites W2345998278 @default.
- W3043237919 cites W2525587647 @default.
- W3043237919 cites W2548906585 @default.
- W3043237919 cites W2579878967 @default.
- W3043237919 cites W2588536181 @default.
- W3043237919 cites W2592206889 @default.
- W3043237919 cites W2606895029 @default.
- W3043237919 cites W2742290492 @default.
- W3043237919 cites W2744975623 @default.
- W3043237919 cites W2750641499 @default.
- W3043237919 cites W2765189155 @default.
- W3043237919 cites W2775062779 @default.
- W3043237919 cites W2782900632 @default.
- W3043237919 cites W2789374786 @default.
- W3043237919 cites W2883250287 @default.
- W3043237919 cites W2884057849 @default.
- W3043237919 cites W2894038927 @default.
- W3043237919 cites W2898104906 @default.
- W3043237919 cites W2912017471 @default.
- W3043237919 cites W2957292952 @default.
- W3043237919 cites W2966625330 @default.
- W3043237919 cites W2967043226 @default.
- W3043237919 cites W2995728636 @default.
- W3043237919 cites W3001886907 @default.
- W3043237919 cites W3003175835 @default.
- W3043237919 cites W3003969359 @default.
- W3043237919 cites W3008089269 @default.
- W3043237919 cites W3009629443 @default.
- W3043237919 cites W3020855961 @default.
- W3043237919 doi "https://doi.org/10.1016/j.gene.2020.144952" @default.
- W3043237919 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32683074" @default.
- W3043237919 hasPublicationYear "2020" @default.
- W3043237919 type Work @default.
- W3043237919 sameAs 3043237919 @default.
- W3043237919 citedByCount "31" @default.
- W3043237919 countsByYear W30432379192021 @default.
- W3043237919 countsByYear W30432379192022 @default.
- W3043237919 countsByYear W30432379192023 @default.
- W3043237919 crossrefType "journal-article" @default.
- W3043237919 hasAuthorship W3043237919A5031524039 @default.
- W3043237919 hasAuthorship W3043237919A5039077688 @default.
- W3043237919 hasAuthorship W3043237919A5052026299 @default.
- W3043237919 hasAuthorship W3043237919A5060741407 @default.
- W3043237919 hasAuthorship W3043237919A5061272605 @default.
- W3043237919 hasAuthorship W3043237919A5061853276 @default.
- W3043237919 hasAuthorship W3043237919A5062755510 @default.
- W3043237919 hasAuthorship W3043237919A5072182447 @default.
- W3043237919 hasConcept C104317684 @default.
- W3043237919 hasConcept C119056186 @default.
- W3043237919 hasConcept C126322002 @default.
- W3043237919 hasConcept C134018914 @default.
- W3043237919 hasConcept C145059251 @default.
- W3043237919 hasConcept C2775893923 @default.
- W3043237919 hasConcept C2779922275 @default.
- W3043237919 hasConcept C2780091579 @default.
- W3043237919 hasConcept C2780559512 @default.
- W3043237919 hasConcept C2781184683 @default.
- W3043237919 hasConcept C2781197716 @default.
- W3043237919 hasConcept C502942594 @default.
- W3043237919 hasConcept C54355233 @default.
- W3043237919 hasConcept C555293320 @default.
- W3043237919 hasConcept C62203573 @default.
- W3043237919 hasConcept C67705224 @default.
- W3043237919 hasConcept C71924100 @default.
- W3043237919 hasConcept C86803240 @default.
- W3043237919 hasConcept C95444343 @default.
- W3043237919 hasConceptScore W3043237919C104317684 @default.
- W3043237919 hasConceptScore W3043237919C119056186 @default.
- W3043237919 hasConceptScore W3043237919C126322002 @default.
- W3043237919 hasConceptScore W3043237919C134018914 @default.
- W3043237919 hasConceptScore W3043237919C145059251 @default.
- W3043237919 hasConceptScore W3043237919C2775893923 @default.