FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3043282815> ?p ?o ?g. }

• W3043282815 abstract "Abstract Bigenic expression relationships are conventionally defined based on metrics such as Pearson or Spearman correlation that cannot typically detect latent, non-linear dependencies or require the relationship to be monotonic. Further, the combination of intrinsic and extrinsic noise as well as embedded relationships between sample sub-populations reduces the probability of extracting biologically relevant edges during the construction of gene co-expression networks (GCNs). In this report, we address these problems via our NetExtractor algorithm. NetExtractor examines all pairwise gene expression profiles first with Gaussian mixture models (GMMs) to identify sample sub-populations followed by mutual information (MI) analysis that is capable of detecting non-linear differential bigenic expression relationships. We applied NetExtractor to brain tissue RNA profiles from the Genotype-Tissue Expression (GTEx) project to obtain a brain tissue specific gene expression relationship network centered on cerebellar and cerebellar hemisphere enriched edges. We leveraged the PsychENCODE pre-frontal cortex (PFC) gene regulatory network (GRN) to construct a cerebellar cortex (cerebellar) GRN associated with transcriptionally active regions in cerebellar tissue. Thus, we demonstrate the utility of our NetExtractor approach to detect biologically relevant and novel non-linear binary gene relationships." @default.
• W3043282815 created "2020-07-23" @default.
• W3043282815 creator A5043213807 @default.
• W3043282815 creator A5060354987 @default.
• W3043282815 creator A5062382318 @default.
• W3043282815 creator A5070911716 @default.
• W3043282815 creator A5071321665 @default.
• W3043282815 creator A5083665803 @default.
• W3043282815 date "2020-09-01" @default.
• W3043282815 modified "2023-10-17" @default.
• W3043282815 title "NetExtractor: Extracting a Cerebellar Tissue Gene Regulatory Network Using Differentially Expressed High Mutual Information Binary RNA Profiles" @default.
• W3043282815 cites W1966327575 @default.
• W3043282815 cites W1987971958 @default.
• W3043282815 cites W1992452843 @default.
• W3043282815 cites W1997432697 @default.
• W3043282815 cites W2003456502 @default.
• W3043282815 cites W2007684630 @default.
• W3043282815 cites W2018838463 @default.
• W3043282815 cites W2044525257 @default.
• W3043282815 cites W2047311093 @default.
• W3043282815 cites W2070494252 @default.
• W3043282815 cites W2111384508 @default.
• W3043282815 cites W2124649657 @default.
• W3043282815 cites W2135650458 @default.
• W3043282815 cites W2150926065 @default.
• W3043282815 cites W2154053567 @default.
• W3043282815 cites W2492873402 @default.
• W3043282815 cites W2586478664 @default.
• W3043282815 cites W2623443302 @default.
• W3043282815 cites W2742474178 @default.
• W3043282815 cites W2757234574 @default.
• W3043282815 cites W2775500188 @default.
• W3043282815 cites W2782783877 @default.
• W3043282815 cites W2796153844 @default.
• W3043282815 cites W2904763455 @default.
• W3043282815 cites W2949158494 @default.
• W3043282815 cites W2965123643 @default.
• W3043282815 cites W4250359879 @default.
• W3043282815 doi "https://doi.org/10.1534/g3.120.401067" @default.
• W3043282815 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7466957" @default.
• W3043282815 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32665353" @default.
• W3043282815 hasPublicationYear "2020" @default.
• W3043282815 type Work @default.
• W3043282815 sameAs 3043282815 @default.
• W3043282815 citedByCount "2" @default.
• W3043282815 countsByYear W30432828152021 @default.
• W3043282815 countsByYear W30432828152022 @default.
• W3043282815 crossrefType "journal-article" @default.
• W3043282815 hasAuthorship W3043282815A5043213807 @default.
• W3043282815 hasAuthorship W3043282815A5060354987 @default.
• W3043282815 hasAuthorship W3043282815A5062382318 @default.
• W3043282815 hasAuthorship W3043282815A5070911716 @default.
• W3043282815 hasAuthorship W3043282815A5071321665 @default.
• W3043282815 hasAuthorship W3043282815A5083665803 @default.
• W3043282815 hasBestOaLocation W30432828151 @default.
• W3043282815 hasConcept C104317684 @default.
• W3043282815 hasConcept C117220453 @default.
• W3043282815 hasConcept C150194340 @default.
• W3043282815 hasConcept C152139883 @default.
• W3043282815 hasConcept C154945302 @default.
• W3043282815 hasConcept C169760540 @default.
• W3043282815 hasConcept C2524010 @default.
• W3043282815 hasConcept C2779652256 @default.
• W3043282815 hasConcept C2779734523 @default.
• W3043282815 hasConcept C2992333117 @default.
• W3043282815 hasConcept C33923547 @default.
• W3043282815 hasConcept C41008148 @default.
• W3043282815 hasConcept C54355233 @default.
• W3043282815 hasConcept C67339327 @default.
• W3043282815 hasConcept C70721500 @default.
• W3043282815 hasConcept C86803240 @default.
• W3043282815 hasConceptScore W3043282815C104317684 @default.
• W3043282815 hasConceptScore W3043282815C117220453 @default.
• W3043282815 hasConceptScore W3043282815C150194340 @default.
• W3043282815 hasConceptScore W3043282815C152139883 @default.
• W3043282815 hasConceptScore W3043282815C154945302 @default.
• W3043282815 hasConceptScore W3043282815C169760540 @default.
• W3043282815 hasConceptScore W3043282815C2524010 @default.
• W3043282815 hasConceptScore W3043282815C2779652256 @default.
• W3043282815 hasConceptScore W3043282815C2779734523 @default.
• W3043282815 hasConceptScore W3043282815C2992333117 @default.
• W3043282815 hasConceptScore W3043282815C33923547 @default.
• W3043282815 hasConceptScore W3043282815C41008148 @default.
• W3043282815 hasConceptScore W3043282815C54355233 @default.
• W3043282815 hasConceptScore W3043282815C67339327 @default.
• W3043282815 hasConceptScore W3043282815C70721500 @default.
• W3043282815 hasConceptScore W3043282815C86803240 @default.
• W3043282815 hasLocation W30432828151 @default.
• W3043282815 hasLocation W30432828152 @default.
• W3043282815 hasOpenAccess W3043282815 @default.
• W3043282815 hasPrimaryLocation W30432828151 @default.
• W3043282815 hasRelatedWork W10495651 @default.
• W3043282815 hasRelatedWork W1620652 @default.
• W3043282815 hasRelatedWork W1737890 @default.
• W3043282815 hasRelatedWork W2229958 @default.
• W3043282815 hasRelatedWork W2826591 @default.
• W3043282815 hasRelatedWork W5190142 @default.
• W3043282815 hasRelatedWork W7087916 @default.
• W3043282815 hasRelatedWork W7194290 @default.
• W3043282815 hasRelatedWork W8918453 @default.

• next