FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3043293329> ?p ?o ?g. }

• W3043293329 endingPage "2785" @default.
• W3043293329 startingPage "2775" @default.
• W3043293329 abstract "Chronic posttraumatic headache (PTH) is among the most common and disabling sequelae of traumatic brain injury (TBI). Current PTH treatments are often only partially effective and have problematic side effects. We previously showed in a small randomized trial of patients with chronic nontraumatic headaches that manipulation of dietary fatty acids decreased headache frequency, severity, and pain medication use. Pain reduction was associated with alterations in oxylipins derived from n-3 and n-6 fatty acids, suggesting that oxylipins could potentially mediate clinical pain reduction. The objective of this study was to investigate whether circulating oxylipins measured in the acute setting after TBI could serve as prognostic biomarkers for developing chronic PTH. Participants enrolled in the Traumatic Head Injury Neuroimaging Classification Protocol provided serum within 3 days of TBI and were followed up at 90 days postinjury with a neurobehavioral symptom inventory (NSI) and satisfaction with life survey. Liquid chromatography-tandem mass spectrometry methods profiled 39 oxylipins derived from n-3 docosahexaenoic acid (DHA), and n-6 arachidonic acid and linoleic acid. Statistical analyses assessed the association of oxylipins with headache severity (primary outcome, measured by headache question on NSI) as well as associations between oxylipins and total NSI or satisfaction with life survey scores. Among oxylipins, 4-hydroxy-DHA and 19,20-epoxy-docosapentaenoate (DHA derivatives) were inversely associated with headache severity, and 11-hydroxy-9-epoxy-octadecenoate (a linoleic acid derivative) was positively associated with headache severity. These findings support a potential for DHA-derived oxylipins as prognostic biomarkers for development of chronic PTH." @default.
• W3043293329 created "2020-07-23" @default.
• W3043293329 creator A5015152899 @default.
• W3043293329 creator A5019756994 @default.
• W3043293329 creator A5045168945 @default.
• W3043293329 creator A5046655200 @default.
• W3043293329 creator A5049758916 @default.
• W3043293329 creator A5056025887 @default.
• W3043293329 creator A5067351916 @default.
• W3043293329 creator A5074910902 @default.
• W3043293329 creator A5081543826 @default.
• W3043293329 date "2020-07-09" @default.
• W3043293329 modified "2023-10-13" @default.
• W3043293329 title "Identifying oxidized lipid mediators as prognostic biomarkers of chronic posttraumatic headache" @default.
• W3043293329 cites W1967884571 @default.
• W3043293329 cites W1970271003 @default.
• W3043293329 cites W1974696826 @default.
• W3043293329 cites W1978858228 @default.
• W3043293329 cites W1987861809 @default.
• W3043293329 cites W2005455675 @default.
• W3043293329 cites W2008574207 @default.
• W3043293329 cites W2031043968 @default.
• W3043293329 cites W2031504469 @default.
• W3043293329 cites W2033451048 @default.
• W3043293329 cites W2034484957 @default.
• W3043293329 cites W2035079236 @default.
• W3043293329 cites W2040831881 @default.
• W3043293329 cites W2042639961 @default.
• W3043293329 cites W2061592052 @default.
• W3043293329 cites W2061710425 @default.
• W3043293329 cites W2062402325 @default.
• W3043293329 cites W2067637071 @default.
• W3043293329 cites W2074833867 @default.
• W3043293329 cites W2075998443 @default.
• W3043293329 cites W2083205008 @default.
• W3043293329 cites W2086794394 @default.
• W3043293329 cites W2090609282 @default.
• W3043293329 cites W2090722957 @default.
• W3043293329 cites W2100773682 @default.
• W3043293329 cites W2116383541 @default.
• W3043293329 cites W2128810790 @default.
• W3043293329 cites W2146125855 @default.
• W3043293329 cites W2146570042 @default.
• W3043293329 cites W2148898267 @default.
• W3043293329 cites W2152077362 @default.
• W3043293329 cites W2152584784 @default.
• W3043293329 cites W2154881563 @default.
• W3043293329 cites W2161340781 @default.
• W3043293329 cites W2166102027 @default.
• W3043293329 cites W2173429194 @default.
• W3043293329 cites W2218888203 @default.
• W3043293329 cites W2254177920 @default.
• W3043293329 cites W2258234778 @default.
• W3043293329 cites W2276634227 @default.
• W3043293329 cites W2294158929 @default.
• W3043293329 cites W2319142315 @default.
• W3043293329 cites W2334447988 @default.
• W3043293329 cites W2440783555 @default.
• W3043293329 cites W2504847267 @default.
• W3043293329 cites W2570207194 @default.
• W3043293329 cites W2583747741 @default.
• W3043293329 cites W2600646995 @default.
• W3043293329 cites W2728162977 @default.
• W3043293329 cites W2745426617 @default.
• W3043293329 cites W2770671416 @default.
• W3043293329 cites W2789093894 @default.
• W3043293329 cites W2795441976 @default.
• W3043293329 cites W2800441622 @default.
• W3043293329 cites W2801085490 @default.
• W3043293329 cites W2886984734 @default.
• W3043293329 cites W2917891702 @default.
• W3043293329 cites W2963537687 @default.
• W3043293329 cites W2971613413 @default.
• W3043293329 cites W3003252712 @default.
• W3043293329 cites W3124410800 @default.
• W3043293329 cites W4233399822 @default.
• W3043293329 cites W4251952903 @default.
• W3043293329 doi "https://doi.org/10.1097/j.pain.0000000000001983" @default.
• W3043293329 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7669546" @default.
• W3043293329 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32694380" @default.
• W3043293329 hasPublicationYear "2020" @default.
• W3043293329 type Work @default.
• W3043293329 sameAs 3043293329 @default.
• W3043293329 citedByCount "10" @default.
• W3043293329 countsByYear W30432933292021 @default.
• W3043293329 countsByYear W30432933292022 @default.
• W3043293329 countsByYear W30432933292023 @default.
• W3043293329 crossrefType "journal-article" @default.
• W3043293329 hasAuthorship W3043293329A5015152899 @default.
• W3043293329 hasAuthorship W3043293329A5019756994 @default.
• W3043293329 hasAuthorship W3043293329A5045168945 @default.
• W3043293329 hasAuthorship W3043293329A5046655200 @default.
• W3043293329 hasAuthorship W3043293329A5049758916 @default.
• W3043293329 hasAuthorship W3043293329A5056025887 @default.
• W3043293329 hasAuthorship W3043293329A5067351916 @default.
• W3043293329 hasAuthorship W3043293329A5074910902 @default.
• W3043293329 hasAuthorship W3043293329A5081543826 @default.
• W3043293329 hasBestOaLocation W30432933292 @default.

• next