Matches in SemOpenAlex for { <https://semopenalex.org/work/W3043296502> ?p ?o ?g. }
- W3043296502 endingPage "10995" @default.
- W3043296502 startingPage "10989" @default.
- W3043296502 abstract "The redox-regulator glutathione (GSH) maintains a specific redox potential to sustain routine cellular activity from oxidative damage. In the early stage of the cell cycle process, the glutathione levels increase in the nuclei for protecting the DNA replication process from reactive oxygen species (ROS). In the first attempt, we developed a new ratiometric fluorescent probe that has provided information about glutathione levels in the nuclei. The UV–vis. absorption of probe GScp has shown a hypsochromic shift from 410 to 350 nm in the presence of GSH. In fluorescence titration, we observed that fluorescence emission of the GScp switched from 510 to 460 nm in the presence of GSH. The self-calibrated probe GScp has shown nearly optimal reversibility in GSH redox dynamics with the dissociation constant 2.47 mM. The probe is ideal for GSH tracking in live cells, as its toxicity has within the safe zone. The probe GScp has validated GSH levels in nucleoli by providing fluorescence images in blue-channel. This finding inspires us to use for validation of GSH dynamics in the nucleoli in the cell cycle process." @default.
- W3043296502 created "2020-07-23" @default.
- W3043296502 creator A5010653274 @default.
- W3043296502 creator A5015421152 @default.
- W3043296502 creator A5022389735 @default.
- W3043296502 creator A5041694704 @default.
- W3043296502 creator A5059823306 @default.
- W3043296502 creator A5068691239 @default.
- W3043296502 creator A5085767277 @default.
- W3043296502 date "2020-07-17" @default.
- W3043296502 modified "2023-09-25" @default.
- W3043296502 title "Highly Chemoselective Self-Calibrated Fluorescent Probe Monitors Glutathione Dynamics in Nucleolus in Live Cells" @default.
- W3043296502 cites W1699447737 @default.
- W3043296502 cites W1969076877 @default.
- W3043296502 cites W1969110934 @default.
- W3043296502 cites W1985797929 @default.
- W3043296502 cites W1998395915 @default.
- W3043296502 cites W2003076361 @default.
- W3043296502 cites W2040759630 @default.
- W3043296502 cites W2044841933 @default.
- W3043296502 cites W2059016903 @default.
- W3043296502 cites W2069079930 @default.
- W3043296502 cites W2071986088 @default.
- W3043296502 cites W2087598382 @default.
- W3043296502 cites W2091911547 @default.
- W3043296502 cites W2098828835 @default.
- W3043296502 cites W2099540110 @default.
- W3043296502 cites W2100811292 @default.
- W3043296502 cites W2141746958 @default.
- W3043296502 cites W2146906245 @default.
- W3043296502 cites W2326202062 @default.
- W3043296502 cites W2526483929 @default.
- W3043296502 cites W2551824955 @default.
- W3043296502 cites W2598958389 @default.
- W3043296502 cites W2608039221 @default.
- W3043296502 cites W2726702329 @default.
- W3043296502 cites W2734464815 @default.
- W3043296502 cites W2745522568 @default.
- W3043296502 cites W2782220253 @default.
- W3043296502 cites W2791085041 @default.
- W3043296502 cites W2793859000 @default.
- W3043296502 cites W2802716896 @default.
- W3043296502 cites W2810865682 @default.
- W3043296502 cites W2859049750 @default.
- W3043296502 cites W2893181160 @default.
- W3043296502 cites W2923161346 @default.
- W3043296502 cites W2944562498 @default.
- W3043296502 cites W2950627161 @default.
- W3043296502 cites W4244170600 @default.
- W3043296502 doi "https://doi.org/10.1021/acs.analchem.9b05175" @default.
- W3043296502 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32674561" @default.
- W3043296502 hasPublicationYear "2020" @default.
- W3043296502 type Work @default.
- W3043296502 sameAs 3043296502 @default.
- W3043296502 citedByCount "19" @default.
- W3043296502 countsByYear W30432965022021 @default.
- W3043296502 countsByYear W30432965022022 @default.
- W3043296502 countsByYear W30432965022023 @default.
- W3043296502 crossrefType "journal-article" @default.
- W3043296502 hasAuthorship W3043296502A5010653274 @default.
- W3043296502 hasAuthorship W3043296502A5015421152 @default.
- W3043296502 hasAuthorship W3043296502A5022389735 @default.
- W3043296502 hasAuthorship W3043296502A5041694704 @default.
- W3043296502 hasAuthorship W3043296502A5059823306 @default.
- W3043296502 hasAuthorship W3043296502A5068691239 @default.
- W3043296502 hasAuthorship W3043296502A5085767277 @default.
- W3043296502 hasConcept C121332964 @default.
- W3043296502 hasConcept C12554922 @default.
- W3043296502 hasConcept C179104552 @default.
- W3043296502 hasConcept C181199279 @default.
- W3043296502 hasConcept C183873130 @default.
- W3043296502 hasConcept C185592680 @default.
- W3043296502 hasConcept C190062978 @default.
- W3043296502 hasConcept C48349386 @default.
- W3043296502 hasConcept C538909803 @default.
- W3043296502 hasConcept C55493867 @default.
- W3043296502 hasConcept C55904794 @default.
- W3043296502 hasConcept C57477423 @default.
- W3043296502 hasConcept C62520636 @default.
- W3043296502 hasConcept C75473681 @default.
- W3043296502 hasConcept C86803240 @default.
- W3043296502 hasConcept C91881484 @default.
- W3043296502 hasConceptScore W3043296502C121332964 @default.
- W3043296502 hasConceptScore W3043296502C12554922 @default.
- W3043296502 hasConceptScore W3043296502C179104552 @default.
- W3043296502 hasConceptScore W3043296502C181199279 @default.
- W3043296502 hasConceptScore W3043296502C183873130 @default.
- W3043296502 hasConceptScore W3043296502C185592680 @default.
- W3043296502 hasConceptScore W3043296502C190062978 @default.
- W3043296502 hasConceptScore W3043296502C48349386 @default.
- W3043296502 hasConceptScore W3043296502C538909803 @default.
- W3043296502 hasConceptScore W3043296502C55493867 @default.
- W3043296502 hasConceptScore W3043296502C55904794 @default.
- W3043296502 hasConceptScore W3043296502C57477423 @default.
- W3043296502 hasConceptScore W3043296502C62520636 @default.
- W3043296502 hasConceptScore W3043296502C75473681 @default.
- W3043296502 hasConceptScore W3043296502C86803240 @default.
- W3043296502 hasConceptScore W3043296502C91881484 @default.