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- W3043452227 abstract "Abstract A lag in the increase in oxygen consumption (MO 2 ) occurs at the start of sustainable exercise in trout. Waterborne dichloroacetate (0.58 and 3.49 mmol l −1 ), a compound which activates pyruvate dehydrogenase (PDH) by inhibiting PDH kinase in muscle, accelerates the increase in MO 2 during the first 10 min of sustainable exercise when velocity is elevated to 75% critical swimming speed in a swim tunnel. There are no effects on MO 2 thereafter or at rest. This indicates that a delay in PDH activation (“metabolic inertia”) contributes to the lag phenomenon." @default.
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- W3043452227 date "2020-08-07" @default.
- W3043452227 modified "2023-10-16" @default.
- W3043452227 title "Dichloroacetate reveals the presence of metabolic inertia at the start of exercise in rainbow trout (<scp><i>Oncorhynchus mykiss</i></scp>,<scp>Walbaum</scp>1792)" @default.
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- W3043452227 doi "https://doi.org/10.1111/jfb.14461" @default.
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