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- W3043456568 abstract "During a disease outbreak/pandemic situation such as COVID-19, researchers are in a prime position to identify and develop peptide-based therapies, which could be more rapidly and cost-effectively advanced into a clinical setting. One drawback of natural peptide drugs, however, is their proteolytic instability; peptidomimetics can help to overcome this caveat. In this review, we summarize peptide and peptide-based therapeutics that target one main entry pathway of SARS-CoV-2, which involves the host ACE2 receptor and viral spike (S) protein interaction. Furthermore, we discuss the advantages of peptidomimetics and other potential targets that have been studied using peptide-based therapeutics for COVID-19." @default.
- W3043456568 created "2020-07-23" @default.
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- W3043456568 date "2020-09-01" @default.
- W3043456568 modified "2023-09-27" @default.
- W3043456568 title "Evidence supporting the use of peptides and peptidomimetics as potential SARS-CoV-2 (COVID-19) therapeutics" @default.
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- W3043456568 doi "https://doi.org/10.4155/fmc-2020-0180" @default.
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