FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3043491686> ?p ?o ?g. }

• W3043491686 abstract "Abstract Background Recent studies have highlighted the important role of long non-coding RNA SNHG16 in various human cancers. Here, we conducted a meta-analysis to investigate the effect of SNHG16 expression on clinicopathological features and prognosis in patients with different kinds of human cancers. Methods We performed a systematic search in electronic databases including PubMed, EMBASE, Cochrane Library and Web of Science, to investigate the potential association between SNHG16 expression and prognostic significance and clinical features in cancer patients. Odds ratios (ORs) or hazards ratios (HRs) with corresponding 95% confidence intervals (95% CIs) were pooled to estimate the prognosis value of SNHG16 by StataSE 15.0 software. Results A total of 16 eligible studies with 1299 patients were enrolled in our meta-analysis. The results revealed that increased expression level of SNHG16 was significantly associated with larger tumor size (OR: 3.357; 95% CI: 2.173–5.185; P < 0.001), advanced TNM stage (OR: 2.930; 95% CI: 1.522–5.640; P = 0.001) and poor histological grade (OR: 3.943; 95% CI: 1.955–7.952; P < 0.001), but not correlated with smoking status ( P = 0.489), sex ( P = 0.932), distant metastasis ( P = 0.052), or lymph node metastasis ( P = 0.155). Moreover, the pooled HR showed that elevated expression SNHG16 was associated with a significantly poorer overall survival (OS) (HR = 1.866, 95% CI: 1.571–2.216, P < 0.001). For the set of cancer types, high expression of SNHG16 was significantly associated with shorter OS in patients with cancers of the urinary system (HR: 2.523, 95% CI:1.540–4.133; P <0.001), digestive system (HR: 2.406, 95% CI:1.556–3.721; P <0.001), and other cancers (including glioma and non-small cell lung cancer) (HR: 1.786, 95% CI:1.406–2.267; P <0.001). Conclusions LncRNA SNHG16 overexpression might serve as an unfavorable prognostic factor, which provides a basis for medical workers to evaluate the prognosis of patients and to help the decision-making process." @default.
• W3043491686 created "2020-07-23" @default.
• W3043491686 creator A5006444996 @default.
• W3043491686 creator A5025619970 @default.
• W3043491686 creator A5025697528 @default.
• W3043491686 creator A5044493695 @default.
• W3043491686 creator A5086842474 @default.
• W3043491686 creator A5086993006 @default.
• W3043491686 date "2020-07-16" @default.
• W3043491686 modified "2023-10-18" @default.
• W3043491686 title "Clinicopathological significance and prognosis of long noncoding RNA SNHG16 expression in human cancers: a meta-analysis" @default.
• W3043491686 cites W2088095316 @default.
• W3043491686 cites W2216283224 @default.
• W3043491686 cites W2465379473 @default.
• W3043491686 cites W2594574412 @default.
• W3043491686 cites W2767129407 @default.
• W3043491686 cites W2768008790 @default.
• W3043491686 cites W2773372810 @default.
• W3043491686 cites W2783395490 @default.
• W3043491686 cites W2790098311 @default.
• W3043491686 cites W2791128115 @default.
• W3043491686 cites W2794138009 @default.
• W3043491686 cites W2795022994 @default.
• W3043491686 cites W2795549746 @default.
• W3043491686 cites W2800497748 @default.
• W3043491686 cites W2803913659 @default.
• W3043491686 cites W2882974266 @default.
• W3043491686 cites W2895434014 @default.
• W3043491686 cites W2898881773 @default.
• W3043491686 cites W2901985612 @default.
• W3043491686 cites W2907244318 @default.
• W3043491686 cites W2910965283 @default.
• W3043491686 cites W2911104932 @default.
• W3043491686 cites W2911470993 @default.
• W3043491686 cites W2915343300 @default.
• W3043491686 cites W2917837889 @default.
• W3043491686 cites W2925207309 @default.
• W3043491686 cites W2925330739 @default.
• W3043491686 cites W2935445595 @default.
• W3043491686 cites W2935706064 @default.
• W3043491686 cites W2937818894 @default.
• W3043491686 cites W2941499367 @default.
• W3043491686 cites W2944378516 @default.
• W3043491686 cites W2951498518 @default.
• W3043491686 cites W2952428693 @default.
• W3043491686 cites W2980490312 @default.
• W3043491686 cites W2995856614 @default.
• W3043491686 cites W2997367648 @default.
• W3043491686 cites W2997630559 @default.
• W3043491686 cites W3007734715 @default.
• W3043491686 cites W3015588906 @default.
• W3043491686 cites W3029863827 @default.
• W3043491686 doi "https://doi.org/10.1186/s12885-020-07149-w" @default.
• W3043491686 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7366298" @default.
• W3043491686 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32677912" @default.
• W3043491686 hasPublicationYear "2020" @default.
• W3043491686 type Work @default.
• W3043491686 sameAs 3043491686 @default.
• W3043491686 citedByCount "2" @default.
• W3043491686 countsByYear W30434916862021 @default.
• W3043491686 countsByYear W30434916862022 @default.
• W3043491686 crossrefType "journal-article" @default.
• W3043491686 hasAuthorship W3043491686A5006444996 @default.
• W3043491686 hasAuthorship W3043491686A5025619970 @default.
• W3043491686 hasAuthorship W3043491686A5025697528 @default.
• W3043491686 hasAuthorship W3043491686A5044493695 @default.
• W3043491686 hasAuthorship W3043491686A5086842474 @default.
• W3043491686 hasAuthorship W3043491686A5086993006 @default.
• W3043491686 hasBestOaLocation W30434916861 @default.
• W3043491686 hasConcept C104317684 @default.
• W3043491686 hasConcept C126322002 @default.
• W3043491686 hasConcept C143998085 @default.
• W3043491686 hasConcept C146357865 @default.
• W3043491686 hasConcept C151730666 @default.
• W3043491686 hasConcept C156957248 @default.
• W3043491686 hasConcept C207103383 @default.
• W3043491686 hasConcept C2776478404 @default.
• W3043491686 hasConcept C2780140570 @default.
• W3043491686 hasConcept C44249647 @default.
• W3043491686 hasConcept C54355233 @default.
• W3043491686 hasConcept C62203573 @default.
• W3043491686 hasConcept C63363279 @default.
• W3043491686 hasConcept C67705224 @default.
• W3043491686 hasConcept C71924100 @default.
• W3043491686 hasConcept C86803240 @default.
• W3043491686 hasConcept C95190672 @default.
• W3043491686 hasConceptScore W3043491686C104317684 @default.
• W3043491686 hasConceptScore W3043491686C126322002 @default.
• W3043491686 hasConceptScore W3043491686C143998085 @default.
• W3043491686 hasConceptScore W3043491686C146357865 @default.
• W3043491686 hasConceptScore W3043491686C151730666 @default.
• W3043491686 hasConceptScore W3043491686C156957248 @default.
• W3043491686 hasConceptScore W3043491686C207103383 @default.
• W3043491686 hasConceptScore W3043491686C2776478404 @default.
• W3043491686 hasConceptScore W3043491686C2780140570 @default.
• W3043491686 hasConceptScore W3043491686C44249647 @default.
• W3043491686 hasConceptScore W3043491686C54355233 @default.
• W3043491686 hasConceptScore W3043491686C62203573 @default.
• W3043491686 hasConceptScore W3043491686C63363279 @default.
• W3043491686 hasConceptScore W3043491686C67705224 @default.

• next