Matches in SemOpenAlex for { <https://semopenalex.org/work/W3043511771> ?p ?o ?g. }
- W3043511771 abstract "In humans, respiratory infections with influenza A viruses can be lethal, but it is unclear whether non-respiratory influenza A infections can be equally lethal. Intraperitoneal infection makes the abdominal and pelvic organs accessible to pathogens because of the circulation of peritoneal fluid throughout the pelvis and abdomen. We found that high-dose intraperitoneal infection in mice with influenza A viruses resulted in severe sclerosis and structural damage in the pancreas, disruption of ovarian follicles, and massive infiltration of immune cells in the uterus. The intraperitoneal infections also caused robust upregulation of proinflammatory mediators including IL-6, BLC, and MIG. In addition, low-dose intraperitoneal infection with one influenza strain provided cross-protection against subsequent intraperitoneal or intranasal challenge with another influenza strain. Our results suggest that low-dose, non-respiratory administration might provide a route for influenza vaccination. Furthermore, these results provide insight on the pathological role of influenza A viruses in high-risk patients, including women and diabetic individuals." @default.
- W3043511771 created "2020-07-23" @default.
- W3043511771 creator A5002673284 @default.
- W3043511771 creator A5005628613 @default.
- W3043511771 creator A5016593630 @default.
- W3043511771 creator A5045922502 @default.
- W3043511771 creator A5059299202 @default.
- W3043511771 creator A5062100228 @default.
- W3043511771 creator A5070164781 @default.
- W3043511771 creator A5077058015 @default.
- W3043511771 creator A5079673030 @default.
- W3043511771 creator A5083957292 @default.
- W3043511771 creator A5087927133 @default.
- W3043511771 date "2020-07-17" @default.
- W3043511771 modified "2023-10-12" @default.
- W3043511771 title "Abdominal and Pelvic Organ Failure Induced by Intraperitoneal Influenza A Virus Infection in Mice" @default.
- W3043511771 cites W1483301458 @default.
- W3043511771 cites W1803730350 @default.
- W3043511771 cites W1965766684 @default.
- W3043511771 cites W1970280544 @default.
- W3043511771 cites W1971182364 @default.
- W3043511771 cites W2002012748 @default.
- W3043511771 cites W2013800646 @default.
- W3043511771 cites W2014373251 @default.
- W3043511771 cites W2019920909 @default.
- W3043511771 cites W2026714701 @default.
- W3043511771 cites W2031547081 @default.
- W3043511771 cites W2034040089 @default.
- W3043511771 cites W2048312842 @default.
- W3043511771 cites W2050949051 @default.
- W3043511771 cites W2065387022 @default.
- W3043511771 cites W2076026689 @default.
- W3043511771 cites W2089731966 @default.
- W3043511771 cites W2105793163 @default.
- W3043511771 cites W2121179754 @default.
- W3043511771 cites W2124907107 @default.
- W3043511771 cites W2126833441 @default.
- W3043511771 cites W2133076197 @default.
- W3043511771 cites W2134242383 @default.
- W3043511771 cites W2135421762 @default.
- W3043511771 cites W2137146240 @default.
- W3043511771 cites W2137593002 @default.
- W3043511771 cites W2139751280 @default.
- W3043511771 cites W2141422125 @default.
- W3043511771 cites W2143210877 @default.
- W3043511771 cites W2148658155 @default.
- W3043511771 cites W2151252994 @default.
- W3043511771 cites W2156140162 @default.
- W3043511771 cites W2160972441 @default.
- W3043511771 cites W2162061747 @default.
- W3043511771 cites W2164916558 @default.
- W3043511771 cites W2168664826 @default.
- W3043511771 cites W2168971343 @default.
- W3043511771 cites W2212855413 @default.
- W3043511771 cites W2250517551 @default.
- W3043511771 cites W2259542544 @default.
- W3043511771 cites W2324838759 @default.
- W3043511771 cites W2409745940 @default.
- W3043511771 cites W2429745182 @default.
- W3043511771 cites W2509783789 @default.
- W3043511771 cites W2593126811 @default.
- W3043511771 cites W2594914749 @default.
- W3043511771 cites W2736423956 @default.
- W3043511771 cites W2756741357 @default.
- W3043511771 cites W2771256621 @default.
- W3043511771 cites W2809587920 @default.
- W3043511771 cites W2892551532 @default.
- W3043511771 cites W2946957023 @default.
- W3043511771 cites W2954834031 @default.
- W3043511771 cites W317634691 @default.
- W3043511771 cites W406417856 @default.
- W3043511771 doi "https://doi.org/10.3389/fmicb.2020.01713" @default.
- W3043511771 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7379156" @default.
- W3043511771 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32765481" @default.
- W3043511771 hasPublicationYear "2020" @default.
- W3043511771 type Work @default.
- W3043511771 sameAs 3043511771 @default.
- W3043511771 citedByCount "4" @default.
- W3043511771 countsByYear W30435117712020 @default.
- W3043511771 countsByYear W30435117712021 @default.
- W3043511771 countsByYear W30435117712022 @default.
- W3043511771 countsByYear W30435117712023 @default.
- W3043511771 crossrefType "journal-article" @default.
- W3043511771 hasAuthorship W3043511771A5002673284 @default.
- W3043511771 hasAuthorship W3043511771A5005628613 @default.
- W3043511771 hasAuthorship W3043511771A5016593630 @default.
- W3043511771 hasAuthorship W3043511771A5045922502 @default.
- W3043511771 hasAuthorship W3043511771A5059299202 @default.
- W3043511771 hasAuthorship W3043511771A5062100228 @default.
- W3043511771 hasAuthorship W3043511771A5070164781 @default.
- W3043511771 hasAuthorship W3043511771A5077058015 @default.
- W3043511771 hasAuthorship W3043511771A5079673030 @default.
- W3043511771 hasAuthorship W3043511771A5083957292 @default.
- W3043511771 hasAuthorship W3043511771A5087927133 @default.
- W3043511771 hasBestOaLocation W30435117711 @default.
- W3043511771 hasConcept C126322002 @default.
- W3043511771 hasConcept C159047783 @default.
- W3043511771 hasConcept C203014093 @default.
- W3043511771 hasConcept C2522874641 @default.
- W3043511771 hasConcept C2779066055 @default.