Matches in SemOpenAlex for { <https://semopenalex.org/work/W3043698168> ?p ?o ?g. }
- W3043698168 abstract "Kawasaki disease (KD) may lead to coronary artery aneurysms (CAA) with potential for thrombosis. We aimed to determine the bleeding risk during thromboprophylaxis regimens with dual and triple therapy.KD patients with medium to large CAAs receiving combination thromboprophylaxis therapy (dual or triple therapy with acetylsalicylic acid (ASA), clopidogrel, low molecular weight heparin (LMWH) or warfarin) were reviewed (1979-2017). Treatment periods <30 days were excluded. Bleeding events were classified using the Bleeding Academic Research Consortium (BARC) Score. The incidence of bleeding events per patient year of exposure was determined for each regimen.n = 98 of 3022 KD (23 females:75 males) were included. Median age at diagnosis was 2.6 years (IQR: 0.6-6.2), median maximum CAA z-score was 18.0 (range: 5-65.5, IQR: 10.8-28.0, m = 6) and median follow-up duration was 6.5 years (IQR: 2.5-20.2). The incidence of type ≥2 bleeds per patient-year for each regimen was 0 (ASA + clopidogrel+LMWH), 0.03 (ASA + clopidogrel), 0.06 (ASA + warfarin), 0.06 (ASA + clopidogrel+warfarin), and 0.1 (ASA + LMWH) in ascending order. 31 bleeding events requiring medical attention (type ≥2) occurred in 30 patients (median age 7.8 years). Of the 17 type ≥2 bleeds on warfarin with an International Normalised Ratio (INR) available, 13 occurred with an INR >3. For patients receiving triple therapy (dual antiplatelet with anticoagulant), there were 57 bleeding events over 20 treatment periods.The overall bleeding risk was low in KD patients receiving combination thromboprophylaxis, and not significantly different across all regimens. Type ≥2 bleeding events that occurred on warfarin were most frequently associated with high INR values." @default.
- W3043698168 created "2020-07-23" @default.
- W3043698168 creator A5003087619 @default.
- W3043698168 creator A5003994527 @default.
- W3043698168 creator A5027489789 @default.
- W3043698168 creator A5066092141 @default.
- W3043698168 creator A5066197445 @default.
- W3043698168 creator A5084628375 @default.
- W3043698168 date "2020-12-01" @default.
- W3043698168 modified "2023-09-29" @default.
- W3043698168 title "Bleeding risk associated with combination thromboprophylaxis therapy is low for patients with coronary artery aneurysms after Kawasaki disease" @default.
- W3043698168 cites W1965317607 @default.
- W3043698168 cites W1968570373 @default.
- W3043698168 cites W1973115281 @default.
- W3043698168 cites W1973294180 @default.
- W3043698168 cites W1978171356 @default.
- W3043698168 cites W1997557994 @default.
- W3043698168 cites W2010463565 @default.
- W3043698168 cites W2010666563 @default.
- W3043698168 cites W2013832305 @default.
- W3043698168 cites W2022506351 @default.
- W3043698168 cites W2030762571 @default.
- W3043698168 cites W2091564976 @default.
- W3043698168 cites W2122779695 @default.
- W3043698168 cites W2152915227 @default.
- W3043698168 cites W2166842262 @default.
- W3043698168 cites W2168248028 @default.
- W3043698168 cites W2468230121 @default.
- W3043698168 cites W2532336617 @default.
- W3043698168 cites W2551338810 @default.
- W3043698168 cites W2604027935 @default.
- W3043698168 cites W2618477649 @default.
- W3043698168 cites W2622322548 @default.
- W3043698168 cites W2749348258 @default.
- W3043698168 cites W2912139642 @default.
- W3043698168 cites W2957544571 @default.
- W3043698168 cites W2963524094 @default.
- W3043698168 cites W2980777371 @default.
- W3043698168 cites W2984091893 @default.
- W3043698168 cites W2987943866 @default.
- W3043698168 cites W2993710538 @default.
- W3043698168 cites W3195281392 @default.
- W3043698168 doi "https://doi.org/10.1016/j.ijcard.2020.07.022" @default.
- W3043698168 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32697954" @default.
- W3043698168 hasPublicationYear "2020" @default.
- W3043698168 type Work @default.
- W3043698168 sameAs 3043698168 @default.
- W3043698168 citedByCount "4" @default.
- W3043698168 countsByYear W30436981682021 @default.
- W3043698168 countsByYear W30436981682023 @default.
- W3043698168 crossrefType "journal-article" @default.
- W3043698168 hasAuthorship W3043698168A5003087619 @default.
- W3043698168 hasAuthorship W3043698168A5003994527 @default.
- W3043698168 hasAuthorship W3043698168A5027489789 @default.
- W3043698168 hasAuthorship W3043698168A5066092141 @default.
- W3043698168 hasAuthorship W3043698168A5066197445 @default.
- W3043698168 hasAuthorship W3043698168A5084628375 @default.
- W3043698168 hasConcept C120665830 @default.
- W3043698168 hasConcept C121332964 @default.
- W3043698168 hasConcept C126322002 @default.
- W3043698168 hasConcept C141071460 @default.
- W3043698168 hasConcept C2776301958 @default.
- W3043698168 hasConcept C2776820930 @default.
- W3043698168 hasConcept C2777628954 @default.
- W3043698168 hasConcept C2777849778 @default.
- W3043698168 hasConcept C2778213512 @default.
- W3043698168 hasConcept C2779161974 @default.
- W3043698168 hasConcept C2780868729 @default.
- W3043698168 hasConcept C2781413609 @default.
- W3043698168 hasConcept C2781423770 @default.
- W3043698168 hasConcept C61511704 @default.
- W3043698168 hasConcept C71924100 @default.
- W3043698168 hasConceptScore W3043698168C120665830 @default.
- W3043698168 hasConceptScore W3043698168C121332964 @default.
- W3043698168 hasConceptScore W3043698168C126322002 @default.
- W3043698168 hasConceptScore W3043698168C141071460 @default.
- W3043698168 hasConceptScore W3043698168C2776301958 @default.
- W3043698168 hasConceptScore W3043698168C2776820930 @default.
- W3043698168 hasConceptScore W3043698168C2777628954 @default.
- W3043698168 hasConceptScore W3043698168C2777849778 @default.
- W3043698168 hasConceptScore W3043698168C2778213512 @default.
- W3043698168 hasConceptScore W3043698168C2779161974 @default.
- W3043698168 hasConceptScore W3043698168C2780868729 @default.
- W3043698168 hasConceptScore W3043698168C2781413609 @default.
- W3043698168 hasConceptScore W3043698168C2781423770 @default.
- W3043698168 hasConceptScore W3043698168C61511704 @default.
- W3043698168 hasConceptScore W3043698168C71924100 @default.
- W3043698168 hasLocation W30436981681 @default.
- W3043698168 hasLocation W30436981682 @default.
- W3043698168 hasOpenAccess W3043698168 @default.
- W3043698168 hasPrimaryLocation W30436981681 @default.
- W3043698168 hasRelatedWork W1456115 @default.
- W3043698168 hasRelatedWork W15351494 @default.
- W3043698168 hasRelatedWork W18992808 @default.
- W3043698168 hasRelatedWork W2517882 @default.
- W3043698168 hasRelatedWork W2845105 @default.
- W3043698168 hasRelatedWork W3142333 @default.
- W3043698168 hasRelatedWork W3438312 @default.
- W3043698168 hasRelatedWork W5207367 @default.
- W3043698168 hasRelatedWork W6544046 @default.