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• W3043809525 endingPage "683" @default.
• W3043809525 startingPage "667" @default.
• W3043809525 abstract "Porcine reproductive and respiratory syndrome virus (PRRSV) remains widespread in the North American pig population. Despite improvements in virus characterization, it is unclear whether PRRSV infections are a product of viral circulation within production systems (local) or across production systems (external). Here, we examined the local and external dissemination dynamics of PRRSV and the processes facilitating its spread in three production systems. Overall, PRRSV genetic diversity has declined since 2018, while phylodynamic results support frequent external transmission. We found that PRRSV dissemination predominantly occurred mostly through transmission between farms of different production companies for several months, especially from November until May, a timeframe already established as PRRSV season. Although local PRRSV dissemination occurred mainly through regular pig flow (from sow to nursery and then to finisher farms), an important flux of PRRSV dissemination also occurred in the opposite direction, from finisher to sow and nursery farms, highlighting the importance of downstream farms as sources of the virus. Our results also showed that farms with pig densities of 500 to 1,000 pig/km2 and farms located at a range within 0.5 km and 0.7 km from major roads were more likely to be infected by PRRSV, whereas farms at an elevation of 41 to 61 meters and surrounded by denser vegetation were less likely to be infected, indicating their role as dissemination barriers. In conclusion, our results demonstrate that external dissemination was intense, and reinforce the importance of farm proximity on PRRSV spread. Thus, consideration of farm location, geographic characteristics and animal densities across production systems may help to forecast PRRSV collateral dissemination." @default.
• W3043809525 created "2020-07-23" @default.
• W3043809525 creator A5058082988 @default.
• W3043809525 creator A5069894931 @default.
• W3043809525 creator A5076802172 @default.
• W3043809525 creator A5080191746 @default.
• W3043809525 date "2020-08-06" @default.
• W3043809525 modified "2023-10-01" @default.
• W3043809525 title "Porcine reproductive and respiratory syndrome virus dissemination across pig production systems in the United States" @default.
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• W3043809525 doi "https://doi.org/10.1111/tbed.13728" @default.
• W3043809525 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32657491" @default.
• W3043809525 hasPublicationYear "2020" @default.
• W3043809525 type Work @default.
• W3043809525 sameAs 3043809525 @default.

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