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- W3043901339 abstract "Considering the limited progress of chemotherapy and targeted therapy in improving the generally disappointing outcomes of advanced gastric or gastroesophageal junction cancer (GC/GEJC), immunotherapies have been gradually developed and advanced into novel frontiers of treatment for advanced GC/GEJC. Nevertheless, the response to immunotherapy was not always satisfactory, and the emergence of resistance was unavoidable. These factors prompt the development of different combination therapies and predictive and prognostic biomarkers of efficacy to improve the outcomes of patients with advanced GC/GEJC and to overcome drug resistance. This article discusses the advances of immune monotherapy, multiple current and ongoing clinical trials of immune combination therapy, immune-related adverse events, and various biomarkers in GC/GEJC." @default.
- W3043901339 created "2020-07-29" @default.
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- W3043901339 date "2020-07-21" @default.
- W3043901339 modified "2023-10-16" @default.
- W3043901339 title "Novel Frontiers of Treatment for Advanced Gastric or Gastroesophageal Junction Cancer (GC/GEJC): Will Immunotherapy Be a Future Direction?" @default.
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- W3043901339 doi "https://doi.org/10.3389/fonc.2020.00912" @default.
- W3043901339 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7386300" @default.
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- W3043901339 hasPublicationYear "2020" @default.
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