Matches in SemOpenAlex for { <https://semopenalex.org/work/W3043952205> ?p ?o ?g. }
- W3043952205 endingPage "1782163" @default.
- W3043952205 startingPage "1782163" @default.
- W3043952205 abstract "Non-communicable diseases, such as the metabolic syndrome and inflammatory bowel disease, constitute serious public health threats in developed countries. Besides environmental factors, genetic predispositions contribute to the onset and progression of the disease. State-of-the-art mouse models recently highlight the involvement of Toll-like receptor 5 (TLR5)-driven microbiota composition in the development of metabolic disorders. Here, we discuss the causes and consequences of an altered enteric microbiota and provide information on a similar mechanism in another species, the pig. We show for the first time that a single nucleotide polymorphism in the porcine TLR5 gene conferring impaired functionality is associated with changes in the intestinal microbiota in adult sows and neonatal piglets. Changes in the developing adaptive cellular immune response support the concept of TLR5-driven changes of the microbe-host interplay also in the pig. Together, these findings suggest that pigs with impaired TLR-functionality might represent a model for TLR5-driven diseases in humans." @default.
- W3043952205 created "2020-07-29" @default.
- W3043952205 creator A5016500615 @default.
- W3043952205 creator A5025384952 @default.
- W3043952205 creator A5036467945 @default.
- W3043952205 creator A5037672153 @default.
- W3043952205 creator A5053060633 @default.
- W3043952205 creator A5073357107 @default.
- W3043952205 creator A5087510784 @default.
- W3043952205 date "2020-07-25" @default.
- W3043952205 modified "2023-09-23" @default.
- W3043952205 title "Toward a porcine in vivo model to analyze the pathogenesis of TLR5-dependent enteropathies" @default.
- W3043952205 cites W1578273550 @default.
- W3043952205 cites W1617145133 @default.
- W3043952205 cites W1965461697 @default.
- W3043952205 cites W1975296949 @default.
- W3043952205 cites W1981389563 @default.
- W3043952205 cites W1989580445 @default.
- W3043952205 cites W2004549986 @default.
- W3043952205 cites W2007336148 @default.
- W3043952205 cites W2012606594 @default.
- W3043952205 cites W2012854889 @default.
- W3043952205 cites W2026472998 @default.
- W3043952205 cites W2027986517 @default.
- W3043952205 cites W2041104984 @default.
- W3043952205 cites W2041136224 @default.
- W3043952205 cites W2042374244 @default.
- W3043952205 cites W2054151627 @default.
- W3043952205 cites W2069752064 @default.
- W3043952205 cites W2079337698 @default.
- W3043952205 cites W2080283023 @default.
- W3043952205 cites W2082741771 @default.
- W3043952205 cites W2084672610 @default.
- W3043952205 cites W2090488505 @default.
- W3043952205 cites W2110235509 @default.
- W3043952205 cites W2111685356 @default.
- W3043952205 cites W2149515881 @default.
- W3043952205 cites W2297994856 @default.
- W3043952205 cites W2467200611 @default.
- W3043952205 cites W2471627592 @default.
- W3043952205 cites W2521321100 @default.
- W3043952205 cites W2522919408 @default.
- W3043952205 cites W2588997555 @default.
- W3043952205 cites W2784989009 @default.
- W3043952205 cites W2798022221 @default.
- W3043952205 cites W2800689200 @default.
- W3043952205 cites W2886322630 @default.
- W3043952205 cites W2888002437 @default.
- W3043952205 cites W2889222907 @default.
- W3043952205 cites W2891084878 @default.
- W3043952205 cites W2894528081 @default.
- W3043952205 cites W2901803103 @default.
- W3043952205 cites W2910577978 @default.
- W3043952205 cites W2949305856 @default.
- W3043952205 cites W2976813133 @default.
- W3043952205 cites W3005446552 @default.
- W3043952205 cites W3008887685 @default.
- W3043952205 doi "https://doi.org/10.1080/19490976.2020.1782163" @default.
- W3043952205 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7524303" @default.
- W3043952205 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32715918" @default.
- W3043952205 hasPublicationYear "2020" @default.
- W3043952205 type Work @default.
- W3043952205 sameAs 3043952205 @default.
- W3043952205 citedByCount "1" @default.
- W3043952205 countsByYear W30439522052021 @default.
- W3043952205 crossrefType "journal-article" @default.
- W3043952205 hasAuthorship W3043952205A5016500615 @default.
- W3043952205 hasAuthorship W3043952205A5025384952 @default.
- W3043952205 hasAuthorship W3043952205A5036467945 @default.
- W3043952205 hasAuthorship W3043952205A5037672153 @default.
- W3043952205 hasAuthorship W3043952205A5053060633 @default.
- W3043952205 hasAuthorship W3043952205A5073357107 @default.
- W3043952205 hasAuthorship W3043952205A5087510784 @default.
- W3043952205 hasBestOaLocation W30439522051 @default.
- W3043952205 hasConcept C136449434 @default.
- W3043952205 hasConcept C203014093 @default.
- W3043952205 hasConcept C207001950 @default.
- W3043952205 hasConcept C2776709828 @default.
- W3043952205 hasConcept C2777338127 @default.
- W3043952205 hasConcept C2780942790 @default.
- W3043952205 hasConcept C54355233 @default.
- W3043952205 hasConcept C86803240 @default.
- W3043952205 hasConcept C8891405 @default.
- W3043952205 hasConceptScore W3043952205C136449434 @default.
- W3043952205 hasConceptScore W3043952205C203014093 @default.
- W3043952205 hasConceptScore W3043952205C207001950 @default.
- W3043952205 hasConceptScore W3043952205C2776709828 @default.
- W3043952205 hasConceptScore W3043952205C2777338127 @default.
- W3043952205 hasConceptScore W3043952205C2780942790 @default.
- W3043952205 hasConceptScore W3043952205C54355233 @default.
- W3043952205 hasConceptScore W3043952205C86803240 @default.
- W3043952205 hasConceptScore W3043952205C8891405 @default.
- W3043952205 hasIssue "1" @default.
- W3043952205 hasLocation W30439522051 @default.
- W3043952205 hasLocation W30439522052 @default.
- W3043952205 hasLocation W30439522053 @default.
- W3043952205 hasOpenAccess W3043952205 @default.
- W3043952205 hasPrimaryLocation W30439522051 @default.