Matches in SemOpenAlex for { <https://semopenalex.org/work/W3044149730> ?p ?o ?g. }
Showing items 1 to 84 of
84
with 100 items per page.
- W3044149730 endingPage "194" @default.
- W3044149730 startingPage "187" @default.
- W3044149730 abstract "Objective The presence of tissue eosinophilia is a determinate of disease severity in patients with chronic rhinosinusitis (CRS). The impact of eosinophilic mucin (EM) as an independent variable has not yet been elucidated. Study Design Retrospective review. Setting Tertiary academic clinic. Subjects Methods: CRS patients who failed medical therapy were classified by tissue eosinophilia, presence of polyps and EM. Tissue eosinophilia count per high power field (HPF) as well as the presence of EM were determined by pathologic examination of sinus tissue removed during surgery. Sinonasal Outcomes Test (SNOT-22), Lund-Mackay (LM), and Lund-Kennedy (LK) scores were compared between all groups preoperatively and postoperatively up to two and a half years (30 months). Results 192 patients with CRS were included in the study. 87 were diagnosed with eosinophilic CRS with polyps, 58 with eosinophilic CRS without polyps, 14 with noneosinophilic CRS with polyps, and 33 with noneosinophilic CRS without polyps. Only patients with eosinophilia had EM on pathology. Of eosinophilic CRS, 50% of patients with polyps and 12% of cases without polyps demonstrated EM, respectively. EM presence portended more severe disease in patients with eosinophilia on subjective and objective scores preoperatively (P < 0.005). Postoperatively, EM patients experienced a greater improvement of symptoms, but continued to have worse endoscopy scores until 1.5 years. A tissue eosinophil count of 30 or greater per HPF was identified as a potential marker for the development of EM. Conclusions The presence of eosinophilic mucin predicts overall worse disease severity in patients with eosinophilic CRS." @default.
- W3044149730 created "2020-07-29" @default.
- W3044149730 creator A5003300606 @default.
- W3044149730 creator A5021331838 @default.
- W3044149730 creator A5050381621 @default.
- W3044149730 creator A5075221078 @default.
- W3044149730 date "2020-07-20" @default.
- W3044149730 modified "2023-10-16" @default.
- W3044149730 title "Eosinophilic Mucin: A Predictor for Disease Severity in Chronic Rhinosinusitis" @default.
- W3044149730 cites W2000228858 @default.
- W3044149730 cites W2019535648 @default.
- W3044149730 cites W2025712618 @default.
- W3044149730 cites W2034162419 @default.
- W3044149730 cites W2058157286 @default.
- W3044149730 cites W2064098644 @default.
- W3044149730 cites W2066318154 @default.
- W3044149730 cites W2079573726 @default.
- W3044149730 cites W2099873243 @default.
- W3044149730 cites W2100263956 @default.
- W3044149730 cites W2169855061 @default.
- W3044149730 cites W2915428636 @default.
- W3044149730 doi "https://doi.org/10.1177/1945892420943828" @default.
- W3044149730 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32689821" @default.
- W3044149730 hasPublicationYear "2020" @default.
- W3044149730 type Work @default.
- W3044149730 sameAs 3044149730 @default.
- W3044149730 citedByCount "4" @default.
- W3044149730 countsByYear W30441497302021 @default.
- W3044149730 countsByYear W30441497302022 @default.
- W3044149730 countsByYear W30441497302023 @default.
- W3044149730 crossrefType "journal-article" @default.
- W3044149730 hasAuthorship W3044149730A5003300606 @default.
- W3044149730 hasAuthorship W3044149730A5021331838 @default.
- W3044149730 hasAuthorship W3044149730A5050381621 @default.
- W3044149730 hasAuthorship W3044149730A5075221078 @default.
- W3044149730 hasConcept C126322002 @default.
- W3044149730 hasConcept C141071460 @default.
- W3044149730 hasConcept C142724271 @default.
- W3044149730 hasConcept C167135981 @default.
- W3044149730 hasConcept C2776042228 @default.
- W3044149730 hasConcept C2777037409 @default.
- W3044149730 hasConcept C2777129736 @default.
- W3044149730 hasConcept C2777768476 @default.
- W3044149730 hasConcept C2779134260 @default.
- W3044149730 hasConcept C2779758542 @default.
- W3044149730 hasConcept C2781390199 @default.
- W3044149730 hasConcept C3019717275 @default.
- W3044149730 hasConcept C71924100 @default.
- W3044149730 hasConcept C90924648 @default.
- W3044149730 hasConceptScore W3044149730C126322002 @default.
- W3044149730 hasConceptScore W3044149730C141071460 @default.
- W3044149730 hasConceptScore W3044149730C142724271 @default.
- W3044149730 hasConceptScore W3044149730C167135981 @default.
- W3044149730 hasConceptScore W3044149730C2776042228 @default.
- W3044149730 hasConceptScore W3044149730C2777037409 @default.
- W3044149730 hasConceptScore W3044149730C2777129736 @default.
- W3044149730 hasConceptScore W3044149730C2777768476 @default.
- W3044149730 hasConceptScore W3044149730C2779134260 @default.
- W3044149730 hasConceptScore W3044149730C2779758542 @default.
- W3044149730 hasConceptScore W3044149730C2781390199 @default.
- W3044149730 hasConceptScore W3044149730C3019717275 @default.
- W3044149730 hasConceptScore W3044149730C71924100 @default.
- W3044149730 hasConceptScore W3044149730C90924648 @default.
- W3044149730 hasIssue "2" @default.
- W3044149730 hasLocation W30441497301 @default.
- W3044149730 hasOpenAccess W3044149730 @default.
- W3044149730 hasPrimaryLocation W30441497301 @default.
- W3044149730 hasRelatedWork W1945572218 @default.
- W3044149730 hasRelatedWork W2165047507 @default.
- W3044149730 hasRelatedWork W2945891409 @default.
- W3044149730 hasRelatedWork W2979050741 @default.
- W3044149730 hasRelatedWork W2999333182 @default.
- W3044149730 hasRelatedWork W3129016566 @default.
- W3044149730 hasRelatedWork W3205539276 @default.
- W3044149730 hasRelatedWork W3206716533 @default.
- W3044149730 hasRelatedWork W4200598779 @default.
- W3044149730 hasRelatedWork W4286355147 @default.
- W3044149730 hasVolume "35" @default.
- W3044149730 isParatext "false" @default.
- W3044149730 isRetracted "false" @default.
- W3044149730 magId "3044149730" @default.
- W3044149730 workType "article" @default.