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- W3044202220 abstract "Developmental toxicity tests are designed to detect xenobiotic agents that affect embryonic development. Embryonic development can be considered a “weak link” in the life cycle of an organism. Developmental toxicants are chemicals that can exert the effects at concentrations lower than that required to affect adults or cause general cellular toxicity. Chronic full life cycle tests account for all significant life stages and usually take longer to run for vertebrates than the 4-d developmental toxicity test presented here. Short-term developmental toxicity tests can then be considered acute or subchronic tests that may predict chronic effects in far less time and cost. In designing a developmental toxicity assay, it is imperative to account for the normal molecular and cellular mechanisms that guide embryonic development. A high-quality binocular dissection microscope and scope light are essential for staging embryos and recording death and malformations." @default.
- W3044202220 created "2020-07-29" @default.
- W3044202220 creator A5081786059 @default.
- W3044202220 date "2020-08-06" @default.
- W3044202220 modified "2023-09-24" @default.
- W3044202220 title "Fetax—A Developmental Toxicity Assay Using Frog Embryos" @default.
- W3044202220 cites W2076612911 @default.
- W3044202220 doi "https://doi.org/10.1201/9781003075363-9" @default.
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