Matches in SemOpenAlex for { <https://semopenalex.org/work/W3044216024> ?p ?o ?g. }
- W3044216024 endingPage "1046" @default.
- W3044216024 startingPage "1035" @default.
- W3044216024 abstract "Nonalcoholic fatty liver disease (NAFLD) is a leading cause of liver disease in the pediatric population. It is a significant liver complication of obesity that also prominently affects children. Over the past decade, several noninvasive methods have been investigated for replacing liver biopsy to identify which children with NAFLD have nonalcoholic steatohepatitis (NASH) and fibrosis. These methods that aim to differentiate the type and extent of liver damage are based on two main different methodologies: a 'biological' approach centered on the quantification of circulating biomarkers; and a 'physical' approach established by analyzing different imaging data.In this review, we illustrate the state of the art and recent discoveries on noninvasive methods for the diagnosis of NAFLD, NASH, and advanced fibrosis.Currently, noninvasive tests cannot diagnose NASH or determine the degree of fibrosis. However, several lines of evidence have suggested that if these tests are used in a complementary way with other laboratory tests and imaging they have the potential to be used to monitor progression of disease and response to therapy in pediatric NAFLD. Future scientific research will focus on combining these methods with multiple potential predictors of genetic susceptibility." @default.
- W3044216024 created "2020-07-29" @default.
- W3044216024 creator A5012723104 @default.
- W3044216024 creator A5040287454 @default.
- W3044216024 creator A5061728147 @default.
- W3044216024 creator A5081639511 @default.
- W3044216024 date "2020-09-07" @default.
- W3044216024 modified "2023-09-30" @default.
- W3044216024 title "Noninvasive diagnostic tools for pediatric NAFLD: where are we now?" @default.
- W3044216024 cites W1528276056 @default.
- W3044216024 cites W1606288352 @default.
- W3044216024 cites W1811353850 @default.
- W3044216024 cites W1937575131 @default.
- W3044216024 cites W1963682935 @default.
- W3044216024 cites W1966224744 @default.
- W3044216024 cites W1980504416 @default.
- W3044216024 cites W1988503635 @default.
- W3044216024 cites W1992719619 @default.
- W3044216024 cites W1994825229 @default.
- W3044216024 cites W1999023976 @default.
- W3044216024 cites W2008317137 @default.
- W3044216024 cites W2009886169 @default.
- W3044216024 cites W2013071753 @default.
- W3044216024 cites W2015026654 @default.
- W3044216024 cites W2019552389 @default.
- W3044216024 cites W2032155479 @default.
- W3044216024 cites W2047253041 @default.
- W3044216024 cites W2050737202 @default.
- W3044216024 cites W2054812545 @default.
- W3044216024 cites W2058324729 @default.
- W3044216024 cites W2060847352 @default.
- W3044216024 cites W2065157689 @default.
- W3044216024 cites W2067740038 @default.
- W3044216024 cites W2073137449 @default.
- W3044216024 cites W2075094829 @default.
- W3044216024 cites W2075886760 @default.
- W3044216024 cites W2082972253 @default.
- W3044216024 cites W2087829753 @default.
- W3044216024 cites W2090739153 @default.
- W3044216024 cites W2095353496 @default.
- W3044216024 cites W2112748532 @default.
- W3044216024 cites W2114716530 @default.
- W3044216024 cites W2118144789 @default.
- W3044216024 cites W2128233799 @default.
- W3044216024 cites W2129152358 @default.
- W3044216024 cites W2139654088 @default.
- W3044216024 cites W2142026804 @default.
- W3044216024 cites W2148436890 @default.
- W3044216024 cites W2153677691 @default.
- W3044216024 cites W2156464269 @default.
- W3044216024 cites W2156792510 @default.
- W3044216024 cites W2164252555 @default.
- W3044216024 cites W2171137806 @default.
- W3044216024 cites W2216434553 @default.
- W3044216024 cites W2252647459 @default.
- W3044216024 cites W2271384303 @default.
- W3044216024 cites W2282195703 @default.
- W3044216024 cites W2293061316 @default.
- W3044216024 cites W2300581094 @default.
- W3044216024 cites W2331952462 @default.
- W3044216024 cites W2345465520 @default.
- W3044216024 cites W2410034883 @default.
- W3044216024 cites W2509438375 @default.
- W3044216024 cites W2522936083 @default.
- W3044216024 cites W2533667526 @default.
- W3044216024 cites W2558403761 @default.
- W3044216024 cites W2561776078 @default.
- W3044216024 cites W2565367159 @default.
- W3044216024 cites W2576488295 @default.
- W3044216024 cites W2591257373 @default.
- W3044216024 cites W2610920244 @default.
- W3044216024 cites W2611354168 @default.
- W3044216024 cites W2612581702 @default.
- W3044216024 cites W2727880778 @default.
- W3044216024 cites W2734077599 @default.
- W3044216024 cites W2734410910 @default.
- W3044216024 cites W2746246230 @default.
- W3044216024 cites W2757178317 @default.
- W3044216024 cites W2757867337 @default.
- W3044216024 cites W2760965813 @default.
- W3044216024 cites W2761134105 @default.
- W3044216024 cites W2762936646 @default.
- W3044216024 cites W2774672890 @default.
- W3044216024 cites W2788104827 @default.
- W3044216024 cites W2799453895 @default.
- W3044216024 cites W2802696143 @default.
- W3044216024 cites W2899521234 @default.
- W3044216024 cites W2909812323 @default.
- W3044216024 cites W2912792291 @default.
- W3044216024 cites W2921381818 @default.
- W3044216024 cites W2924147460 @default.
- W3044216024 cites W2924616125 @default.
- W3044216024 cites W2931356567 @default.
- W3044216024 cites W2941033601 @default.
- W3044216024 cites W2947182926 @default.
- W3044216024 cites W2955630694 @default.
- W3044216024 cites W2961472722 @default.
- W3044216024 cites W2964476833 @default.