Matches in SemOpenAlex for { <https://semopenalex.org/work/W3044349188> ?p ?o ?g. }
- W3044349188 endingPage "1675" @default.
- W3044349188 startingPage "1669" @default.
- W3044349188 abstract "Abstract Bioorthogonal cleavage reactions are gaining popularity in chemically inducible prodrug activation and in the control of biomolecular functions. Despite similar applications, these reactions were developed and optimized on different substrates and under different experimental conditions. Reported herein is a side‐by‐side comparison of palladium‐, ruthenium‐ and tetrazine‐triggered release reactions, which aims at comparing the reaction kinetics, efficiency and overall advantages and limitations of the methods. In addition, we disclose the possibility of mutual combination of the cleavage reactions. Finally, we compare the efficiency of the bioorthogonal deprotections in cellular experiments, which revealed that among the three methods investigated, the palladium‐ and the tetrazine‐promoted reaction can be used for efficient prodrug activation, but only the tetrazine‐triggered reactions proceed efficiently inside cells." @default.
- W3044349188 created "2020-07-29" @default.
- W3044349188 creator A5012134623 @default.
- W3044349188 creator A5030352695 @default.
- W3044349188 creator A5031410622 @default.
- W3044349188 creator A5041434315 @default.
- W3044349188 creator A5047151797 @default.
- W3044349188 date "2020-08-01" @default.
- W3044349188 modified "2023-09-30" @default.
- W3044349188 title "Transition‐Metal‐Mediated versus Tetrazine‐Triggered Bioorthogonal Release Reactions: Direct Comparison and Combinations Thereof" @default.
- W3044349188 cites W1598189694 @default.
- W3044349188 cites W1899140606 @default.
- W3044349188 cites W1945627170 @default.
- W3044349188 cites W1971805692 @default.
- W3044349188 cites W1972257010 @default.
- W3044349188 cites W1978407833 @default.
- W3044349188 cites W1980288318 @default.
- W3044349188 cites W2013557200 @default.
- W3044349188 cites W2028118300 @default.
- W3044349188 cites W2051164897 @default.
- W3044349188 cites W2076402046 @default.
- W3044349188 cites W2085277655 @default.
- W3044349188 cites W2108439421 @default.
- W3044349188 cites W2149472684 @default.
- W3044349188 cites W2157348216 @default.
- W3044349188 cites W2283105825 @default.
- W3044349188 cites W2427310931 @default.
- W3044349188 cites W2492576295 @default.
- W3044349188 cites W2513089562 @default.
- W3044349188 cites W2530773901 @default.
- W3044349188 cites W2544860666 @default.
- W3044349188 cites W2554848955 @default.
- W3044349188 cites W2559751536 @default.
- W3044349188 cites W2607455836 @default.
- W3044349188 cites W2617577749 @default.
- W3044349188 cites W2623161424 @default.
- W3044349188 cites W2734381642 @default.
- W3044349188 cites W2787623985 @default.
- W3044349188 cites W2799384328 @default.
- W3044349188 cites W2800788936 @default.
- W3044349188 cites W2801101371 @default.
- W3044349188 cites W2803170651 @default.
- W3044349188 cites W2808739041 @default.
- W3044349188 cites W2817461677 @default.
- W3044349188 cites W2884819324 @default.
- W3044349188 cites W2891001832 @default.
- W3044349188 cites W2892264210 @default.
- W3044349188 cites W2900070484 @default.
- W3044349188 cites W2913905783 @default.
- W3044349188 cites W2989478509 @default.
- W3044349188 cites W4234531650 @default.
- W3044349188 cites W4249115568 @default.
- W3044349188 cites W4251778703 @default.
- W3044349188 cites W4253739430 @default.
- W3044349188 cites W4386008417 @default.
- W3044349188 doi "https://doi.org/10.1002/cplu.202000477" @default.
- W3044349188 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32757364" @default.
- W3044349188 hasPublicationYear "2020" @default.
- W3044349188 type Work @default.
- W3044349188 sameAs 3044349188 @default.
- W3044349188 citedByCount "8" @default.
- W3044349188 countsByYear W30443491882020 @default.
- W3044349188 countsByYear W30443491882021 @default.
- W3044349188 countsByYear W30443491882022 @default.
- W3044349188 countsByYear W30443491882023 @default.
- W3044349188 crossrefType "journal-article" @default.
- W3044349188 hasAuthorship W3044349188A5012134623 @default.
- W3044349188 hasAuthorship W3044349188A5030352695 @default.
- W3044349188 hasAuthorship W3044349188A5031410622 @default.
- W3044349188 hasAuthorship W3044349188A5041434315 @default.
- W3044349188 hasAuthorship W3044349188A5047151797 @default.
- W3044349188 hasConcept C108215921 @default.
- W3044349188 hasConcept C121332964 @default.
- W3044349188 hasConcept C127413603 @default.
- W3044349188 hasConcept C148898269 @default.
- W3044349188 hasConcept C161790260 @default.
- W3044349188 hasConcept C175156509 @default.
- W3044349188 hasConcept C178790620 @default.
- W3044349188 hasConcept C185592680 @default.
- W3044349188 hasConcept C187320778 @default.
- W3044349188 hasConcept C21951064 @default.
- W3044349188 hasConcept C2778754187 @default.
- W3044349188 hasConcept C43369102 @default.
- W3044349188 hasConcept C55493867 @default.
- W3044349188 hasConcept C555196967 @default.
- W3044349188 hasConcept C62520636 @default.
- W3044349188 hasConcept C69610077 @default.
- W3044349188 hasConcept C930959 @default.
- W3044349188 hasConceptScore W3044349188C108215921 @default.
- W3044349188 hasConceptScore W3044349188C121332964 @default.
- W3044349188 hasConceptScore W3044349188C127413603 @default.
- W3044349188 hasConceptScore W3044349188C148898269 @default.
- W3044349188 hasConceptScore W3044349188C161790260 @default.
- W3044349188 hasConceptScore W3044349188C175156509 @default.
- W3044349188 hasConceptScore W3044349188C178790620 @default.
- W3044349188 hasConceptScore W3044349188C185592680 @default.
- W3044349188 hasConceptScore W3044349188C187320778 @default.
- W3044349188 hasConceptScore W3044349188C21951064 @default.