Matches in SemOpenAlex for { <https://semopenalex.org/work/W3044352214> ?p ?o ?g. }
- W3044352214 endingPage "1657" @default.
- W3044352214 startingPage "1657" @default.
- W3044352214 abstract "In this paper, we perform computer simulation of two lysine-based dendrimers with Lys-2Lys and Lys-2Gly repeating units. These dendrimers were recently studied experimentally by NMR (Sci. Reports, 2018, 8, 8916) and tested as carriers for gene delivery (Bioorg. Chem., 2020, 95, 103504). Simulation was performed by molecular dynamics method in a wide range of temperatures. We have shown that the Lys-2Lys dendrimer has a larger size but smaller fluctuations as well as lower internal density in comparison with the Lys-2Gly dendrimer. The Lys-2Lys dendrimer has larger charge but counterions form more ion pairs with its NH 3 + groups and reduce the bare charge and zeta potential of the first dendrimer more strongly. It was demonstrated that these differences between dendrimers are due to the lower flexibility and the larger charge (+2) of each 2Lys spacers in comparison with 2Gly ones. The terminal CH2 groups in both dendrimers move faster than the inner CH2 groups. The calculated temperature dependencies of the spin-lattice relaxation times of these groups for both dendrimers are in a good agreement with the experimental results obtained by NMR." @default.
- W3044352214 created "2020-07-29" @default.
- W3044352214 creator A5001580715 @default.
- W3044352214 creator A5005523800 @default.
- W3044352214 creator A5011060047 @default.
- W3044352214 creator A5017951718 @default.
- W3044352214 creator A5023630243 @default.
- W3044352214 creator A5025077067 @default.
- W3044352214 creator A5063856037 @default.
- W3044352214 date "2020-07-25" @default.
- W3044352214 modified "2023-09-28" @default.
- W3044352214 title "Comparison of Structure and Local Dynamics of Two Peptide Dendrimers with the Same Backbone but with Different Side Groups in Their Spacers" @default.
- W3044352214 cites W1031578623 @default.
- W3044352214 cites W1542936893 @default.
- W3044352214 cites W176010038 @default.
- W3044352214 cites W1963741796 @default.
- W3044352214 cites W1965103601 @default.
- W3044352214 cites W1969274325 @default.
- W3044352214 cites W1969358827 @default.
- W3044352214 cites W1969835583 @default.
- W3044352214 cites W1970755977 @default.
- W3044352214 cites W1974686741 @default.
- W3044352214 cites W1976689981 @default.
- W3044352214 cites W1979571273 @default.
- W3044352214 cites W1986004569 @default.
- W3044352214 cites W1986647135 @default.
- W3044352214 cites W1986937903 @default.
- W3044352214 cites W1987327282 @default.
- W3044352214 cites W1988680128 @default.
- W3044352214 cites W1992226382 @default.
- W3044352214 cites W1992620470 @default.
- W3044352214 cites W1994936258 @default.
- W3044352214 cites W1995323554 @default.
- W3044352214 cites W2001772905 @default.
- W3044352214 cites W2007359536 @default.
- W3044352214 cites W2008107018 @default.
- W3044352214 cites W2011085652 @default.
- W3044352214 cites W2012326253 @default.
- W3044352214 cites W2013066152 @default.
- W3044352214 cites W2019120007 @default.
- W3044352214 cites W2021294436 @default.
- W3044352214 cites W2024400771 @default.
- W3044352214 cites W2024433496 @default.
- W3044352214 cites W2025014632 @default.
- W3044352214 cites W2029566389 @default.
- W3044352214 cites W2032474521 @default.
- W3044352214 cites W2034067379 @default.
- W3044352214 cites W2035266068 @default.
- W3044352214 cites W2045453481 @default.
- W3044352214 cites W2047148906 @default.
- W3044352214 cites W2047150001 @default.
- W3044352214 cites W2053227378 @default.
- W3044352214 cites W2054188127 @default.
- W3044352214 cites W2055366590 @default.
- W3044352214 cites W2057581357 @default.
- W3044352214 cites W2059397448 @default.
- W3044352214 cites W2064042415 @default.
- W3044352214 cites W2064554825 @default.
- W3044352214 cites W2065201621 @default.
- W3044352214 cites W2067105792 @default.
- W3044352214 cites W2071506921 @default.
- W3044352214 cites W2072192656 @default.
- W3044352214 cites W2072373440 @default.
- W3044352214 cites W2072793559 @default.
- W3044352214 cites W2072959420 @default.
- W3044352214 cites W2074475742 @default.
- W3044352214 cites W2077064239 @default.
- W3044352214 cites W2081002368 @default.
- W3044352214 cites W2081693079 @default.
- W3044352214 cites W2082267567 @default.
- W3044352214 cites W2091329712 @default.
- W3044352214 cites W2091710077 @default.
- W3044352214 cites W2092278908 @default.
- W3044352214 cites W2093757883 @default.
- W3044352214 cites W2093881907 @default.
- W3044352214 cites W2103170230 @default.
- W3044352214 cites W2115038320 @default.
- W3044352214 cites W2122978617 @default.
- W3044352214 cites W2124096526 @default.
- W3044352214 cites W2128327935 @default.
- W3044352214 cites W2129244964 @default.
- W3044352214 cites W2130553306 @default.
- W3044352214 cites W2133661231 @default.
- W3044352214 cites W2134707808 @default.
- W3044352214 cites W2140063056 @default.
- W3044352214 cites W2142177142 @default.
- W3044352214 cites W2143360230 @default.
- W3044352214 cites W2148066125 @default.
- W3044352214 cites W2150787341 @default.
- W3044352214 cites W2153234034 @default.
- W3044352214 cites W2160593570 @default.
- W3044352214 cites W2161605421 @default.
- W3044352214 cites W2275528056 @default.
- W3044352214 cites W2290440383 @default.
- W3044352214 cites W2297815823 @default.
- W3044352214 cites W2397484001 @default.
- W3044352214 cites W2430866394 @default.
- W3044352214 cites W2470577535 @default.