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- W3044431405 endingPage "1775" @default.
- W3044431405 startingPage "1766" @default.
- W3044431405 abstract "Porphyrin photosensitizers are widely used in photodynamic therapy (PDT) because of their unique diagnostic and therapeutic functions. However, many factors such as poor water solubility and instability of porphyrin compounds have limited their clinical application. Metal-organic frameworks (MOFs) have the beneficial characteristics of versatility, high porosity, and excellent biocompatibility. Porphyrin-MOF nanomaterials have attracted the attention of researchers because MOFs can effectively suppress the quenching caused by the self-aggregation of porphyrin compounds and promote drug delivery. This article reviews the latest applications of porphyrin-MOF nanomedicine in type II photodynamic therapy by increasing tumour cell oxygen concentration, depleting tumour cell functional molecules and releasing signal molecules. Current potential limitations and future applications are also emphasized and discussed herein." @default.
- W3044431405 created "2020-07-29" @default.
- W3044431405 creator A5019255400 @default.
- W3044431405 creator A5052292532 @default.
- W3044431405 creator A5052944983 @default.
- W3044431405 creator A5058800301 @default.
- W3044431405 creator A5074854719 @default.
- W3044431405 creator A5085649615 @default.
- W3044431405 creator A5089555055 @default.
- W3044431405 date "2020-08-31" @default.
- W3044431405 modified "2023-10-10" @default.
- W3044431405 title "Porphyrin‐Based Metal−Organic Framework Compounds as Promising Nanomedicines in Photodynamic Therapy" @default.
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