Matches in SemOpenAlex for { <https://semopenalex.org/work/W3044439973> ?p ?o ?g. }
Showing items 1 to 80 of
80
with 100 items per page.
- W3044439973 endingPage "532" @default.
- W3044439973 startingPage "526" @default.
- W3044439973 abstract "Study of inherited heart diseases (IHD) involves performing diagnostic tests, which are sometimes inconvenient or stressful, in asymptomatic relatives. The aim of this study was to analyze refusal to undergo various diagnostic tests and follow therapeutic recommendations. We assessed 1992 consecutive families with IHD to analyze refusal to undergo family screening. The study included 1539 individuals who were recommended to undergo cardiac magnetic resonance, and 837 who were recommended a drug challenge test. To study treatment refusal, we assessed 395 patients with an indication for an implantable cardioverter-defibrillator (ICD) and 402 patients with an indication for anticoagulation. A total of 28% of families who were recommended to undergo screening for suspected IHD did not attend, but refusal was lower if there was a family history of sudden cardiac death. In all, 23% did not undergo magnetic resonance, and the 2 main reasons were administrative problems (53%) and claustrophobia (18%). Refusal was more common in older people, women, symptomatic persons, individuals with arrhythmias, and relatives. Nearly one fifth (19%) did not take the drug challenge test, due to fear (46%) or administrative issues (25%). Refusal was more frequent in older individuals, asymptomatic persons, those with a history of arrhythmias, relatives, and those with a positive genetic study. Only a minority of patients rejected the treatments (5.1% ICD, 2.5% anticoagulation). The percentage of sudden cardiac death in persons rejecting ICD implantation was high (4.5% per year). One fifth of people attending screening for IHD refused to undergo more sophisticated and stressful tests. This study identified several independent predictors associated with refusal. Only a minority of high-risk patients refused treatments such as ICD implantation and anticoagulation. El estudio de las cardiopatías familiares implica realizar pruebas diagnósticas, a veces molestas, a familiares asintomáticos. El objetivo de este proyecto es cuantificar el rechazo a dichas pruebas y recomendaciones terapéuticas. Se evaluó a 1.992 familias consecutivas con cardiopatías familiares para analizar el rechazo al cribado familiar. Se evaluó a 1.539 (recomendación de cardiorresonancia) y 837 (recomendación de test de provocación farmacológica). Se evaluó a 395 pacientes con indicación de desfibrilador automático implantable (DAI) y 402 con indicación de anticoagulación, para estudiar el rechazo de los tratamientos. El 28% de las familias a las que se recomienda estudio por sospecha de cardiopatía familiar no acuden; el rechazo es menor si hay antecedentes familiares de muerte súbita. El 23% no se sometió a la resonancia; los 2 motivos más alegados son citación imposible (53%) y claustrofobia (18%). Las personas de más edad, las mujeres, los sintomáticos, los individuos con arritmias y los familiares rechazaron más la prueba. El 19% no se hizo el test de provocación farmacológica por temor (46%) o citación imposible (25%). Los individuos de más edad, los asintomáticos, aquellos con antecedente de arritmias, los familiares y aquellos con estudio genético positivo lo rechazaron en mayor proporción. Solo una minoría de pacientes rechazaron los tratamientos (el 5,1% el DAI y el 2,5% la anticoagulación). La tasa de muerte súbita entre los que rechazaron el DAI fue alta (el 4,5% al año). Una quinta parte de las personas que acuden al cribado de cardiopatías familiares rechazan la realización de pruebas más sofisticadas y molestas. Se identifican varios predictores independientes asociados con el rechazo. Solo una minoría de pacientes en alto riesgo rechazan los tratamientos como la anticoagulación o el implante de DAI." @default.
- W3044439973 created "2020-07-29" @default.
- W3044439973 creator A5015009665 @default.
- W3044439973 creator A5030028098 @default.
- W3044439973 creator A5037871398 @default.
- W3044439973 creator A5038635082 @default.
- W3044439973 creator A5051361395 @default.
- W3044439973 creator A5062130513 @default.
- W3044439973 creator A5066405003 @default.
- W3044439973 creator A5072305978 @default.
- W3044439973 creator A5082697043 @default.
- W3044439973 creator A5084878216 @default.
- W3044439973 date "2021-06-01" @default.
- W3044439973 modified "2023-10-13" @default.
- W3044439973 title "Reasons for refusing diagnostic tests and therapeutic recommendations and associated complications in inherited heart diseases. The RELUCTANT study" @default.
- W3044439973 cites W2013880873 @default.
- W3044439973 cites W2019924386 @default.
- W3044439973 cites W2039032991 @default.
- W3044439973 cites W2113474470 @default.
- W3044439973 cites W2132248940 @default.
- W3044439973 cites W2171905803 @default.
- W3044439973 cites W2190288765 @default.
- W3044439973 cites W2264374276 @default.
- W3044439973 cites W2755887165 @default.
- W3044439973 doi "https://doi.org/10.1016/j.rec.2020.06.014" @default.
- W3044439973 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32709565" @default.
- W3044439973 hasPublicationYear "2021" @default.
- W3044439973 type Work @default.
- W3044439973 sameAs 3044439973 @default.
- W3044439973 citedByCount "0" @default.
- W3044439973 crossrefType "journal-article" @default.
- W3044439973 hasAuthorship W3044439973A5015009665 @default.
- W3044439973 hasAuthorship W3044439973A5030028098 @default.
- W3044439973 hasAuthorship W3044439973A5037871398 @default.
- W3044439973 hasAuthorship W3044439973A5038635082 @default.
- W3044439973 hasAuthorship W3044439973A5051361395 @default.
- W3044439973 hasAuthorship W3044439973A5062130513 @default.
- W3044439973 hasAuthorship W3044439973A5066405003 @default.
- W3044439973 hasAuthorship W3044439973A5072305978 @default.
- W3044439973 hasAuthorship W3044439973A5082697043 @default.
- W3044439973 hasAuthorship W3044439973A5084878216 @default.
- W3044439973 hasConcept C118552586 @default.
- W3044439973 hasConcept C126322002 @default.
- W3044439973 hasConcept C187212893 @default.
- W3044439973 hasConcept C2775935837 @default.
- W3044439973 hasConcept C2777910003 @default.
- W3044439973 hasConcept C2780673598 @default.
- W3044439973 hasConcept C2781179581 @default.
- W3044439973 hasConcept C2993353509 @default.
- W3044439973 hasConcept C71924100 @default.
- W3044439973 hasConceptScore W3044439973C118552586 @default.
- W3044439973 hasConceptScore W3044439973C126322002 @default.
- W3044439973 hasConceptScore W3044439973C187212893 @default.
- W3044439973 hasConceptScore W3044439973C2775935837 @default.
- W3044439973 hasConceptScore W3044439973C2777910003 @default.
- W3044439973 hasConceptScore W3044439973C2780673598 @default.
- W3044439973 hasConceptScore W3044439973C2781179581 @default.
- W3044439973 hasConceptScore W3044439973C2993353509 @default.
- W3044439973 hasConceptScore W3044439973C71924100 @default.
- W3044439973 hasIssue "6" @default.
- W3044439973 hasLocation W30444399731 @default.
- W3044439973 hasOpenAccess W3044439973 @default.
- W3044439973 hasPrimaryLocation W30444399731 @default.
- W3044439973 hasRelatedWork W1628006525 @default.
- W3044439973 hasRelatedWork W2000243941 @default.
- W3044439973 hasRelatedWork W2084994073 @default.
- W3044439973 hasRelatedWork W2166004591 @default.
- W3044439973 hasRelatedWork W2228079946 @default.
- W3044439973 hasRelatedWork W2331349269 @default.
- W3044439973 hasRelatedWork W2605968981 @default.
- W3044439973 hasRelatedWork W2807880499 @default.
- W3044439973 hasRelatedWork W3034134719 @default.
- W3044439973 hasRelatedWork W3159644355 @default.
- W3044439973 hasVolume "74" @default.
- W3044439973 isParatext "false" @default.
- W3044439973 isRetracted "false" @default.
- W3044439973 magId "3044439973" @default.
- W3044439973 workType "article" @default.