Matches in SemOpenAlex for { <https://semopenalex.org/work/W3044498664> ?p ?o ?g. }
- W3044498664 endingPage "131418" @default.
- W3044498664 startingPage "131418" @default.
- W3044498664 abstract "Abstract Heteroarene-fused derivatives of anthraquinone (anthracene-9,10-dione) represent an exceptionally productive class for the search for new anticancer compounds with improved properties. In this study, we report a convenient heterocyclization, which in three steps leads to 2-alkyl-, aryl-, or hydroxyl derivatives of 5,12-dimethoxynaphtho [2,3-g]quinoline-3-carboxylic acid esters. The scheme includes an alkylation of CH-acids with 2-(bromomethyl)-1,4-dimethoxy-3-nitroanthraquinone (8) followed by reductive cyclization and oxidative aromatization. To increase the series of naphtho [2,3-g]quinoline derivatives, a mild and effective PyBOP-mediated functionalization was developed, which introduced N-, S-, and O-nucleophiles at the 2-position of the quinoline core. We believe that this study allows to access a broad family of 2-substituted naphtho [2,3-g]quinolines and can be adapted for other quinoline derivatives or polyaromatic analogs." @default.
- W3044498664 created "2020-07-29" @default.
- W3044498664 creator A5009576349 @default.
- W3044498664 creator A5012243483 @default.
- W3044498664 creator A5013664216 @default.
- W3044498664 creator A5019712475 @default.
- W3044498664 creator A5041986072 @default.
- W3044498664 date "2020-09-01" @default.
- W3044498664 modified "2023-10-18" @default.
- W3044498664 title "A facile access to 2-substituted naphtho[2,3-g]quinoline-3-carboxylic acid esters via intramolecular cyclization and PyBOP-promoted functionalization" @default.
- W3044498664 cites W1965429141 @default.
- W3044498664 cites W1980849091 @default.
- W3044498664 cites W1993891763 @default.
- W3044498664 cites W1995020832 @default.
- W3044498664 cites W2016505247 @default.
- W3044498664 cites W2045976659 @default.
- W3044498664 cites W2048726724 @default.
- W3044498664 cites W2050522050 @default.
- W3044498664 cites W2051762921 @default.
- W3044498664 cites W2059857891 @default.
- W3044498664 cites W2067956261 @default.
- W3044498664 cites W2070279545 @default.
- W3044498664 cites W2080047273 @default.
- W3044498664 cites W2084232258 @default.
- W3044498664 cites W2100024004 @default.
- W3044498664 cites W2101595998 @default.
- W3044498664 cites W2123240591 @default.
- W3044498664 cites W2137344483 @default.
- W3044498664 cites W2141709303 @default.
- W3044498664 cites W2172467646 @default.
- W3044498664 cites W2177274507 @default.
- W3044498664 cites W2203110083 @default.
- W3044498664 cites W2297509256 @default.
- W3044498664 cites W2342812346 @default.
- W3044498664 cites W2495280073 @default.
- W3044498664 cites W2496004022 @default.
- W3044498664 cites W2500524559 @default.
- W3044498664 cites W2505467044 @default.
- W3044498664 cites W2512472477 @default.
- W3044498664 cites W2525845750 @default.
- W3044498664 cites W2562585861 @default.
- W3044498664 cites W2564512639 @default.
- W3044498664 cites W2568519050 @default.
- W3044498664 cites W2571923702 @default.
- W3044498664 cites W2586022498 @default.
- W3044498664 cites W2591903106 @default.
- W3044498664 cites W2599028570 @default.
- W3044498664 cites W2612979924 @default.
- W3044498664 cites W2755917746 @default.
- W3044498664 cites W2756314682 @default.
- W3044498664 cites W2769048765 @default.
- W3044498664 cites W2771844116 @default.
- W3044498664 cites W2774877147 @default.
- W3044498664 cites W2789458214 @default.
- W3044498664 cites W2883531020 @default.
- W3044498664 cites W2883934783 @default.
- W3044498664 cites W2884566844 @default.
- W3044498664 cites W2893666374 @default.
- W3044498664 cites W2897085410 @default.
- W3044498664 cites W2904659855 @default.
- W3044498664 cites W2911699601 @default.
- W3044498664 cites W2912496199 @default.
- W3044498664 cites W2916625578 @default.
- W3044498664 cites W2945999148 @default.
- W3044498664 cites W2951147988 @default.
- W3044498664 cites W2951553936 @default.
- W3044498664 cites W2951575757 @default.
- W3044498664 cites W2954295861 @default.
- W3044498664 cites W2964969373 @default.
- W3044498664 cites W2965832333 @default.
- W3044498664 cites W2974686794 @default.
- W3044498664 cites W2975188572 @default.
- W3044498664 cites W3000930224 @default.
- W3044498664 cites W3022749109 @default.
- W3044498664 cites W3022970744 @default.
- W3044498664 cites W2952611613 @default.
- W3044498664 doi "https://doi.org/10.1016/j.tet.2020.131418" @default.
- W3044498664 hasPublicationYear "2020" @default.
- W3044498664 type Work @default.
- W3044498664 sameAs 3044498664 @default.
- W3044498664 citedByCount "1" @default.
- W3044498664 countsByYear W30444986642022 @default.
- W3044498664 crossrefType "journal-article" @default.
- W3044498664 hasAuthorship W3044498664A5009576349 @default.
- W3044498664 hasAuthorship W3044498664A5012243483 @default.
- W3044498664 hasAuthorship W3044498664A5013664216 @default.
- W3044498664 hasAuthorship W3044498664A5019712475 @default.
- W3044498664 hasAuthorship W3044498664A5041986072 @default.
- W3044498664 hasConcept C115537861 @default.
- W3044498664 hasConcept C147789679 @default.
- W3044498664 hasConcept C178790620 @default.
- W3044498664 hasConcept C185592680 @default.
- W3044498664 hasConcept C21951064 @default.
- W3044498664 hasConcept C2776309666 @default.
- W3044498664 hasConcept C2779074116 @default.
- W3044498664 hasConcept C75079739 @default.
- W3044498664 hasConceptScore W3044498664C115537861 @default.
- W3044498664 hasConceptScore W3044498664C147789679 @default.