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- W3044508467 abstract "Chapter 3 covers the basic neural mechanisms by which the brain undergoes an extreme makeover during adolescence. It starts with the proposition that the nervous system has only so many tools in the toolbox to accomplish this makeover and these tools can be categorized as either progressive or regressive. Progressive tools include neurogenesis, migration, axon outgrowth, and synapse formation. Regressive tools include programmed cell death and experience-dependent synapse elimination. Two analogies are used to help readers understand this process: house remodeling and gardening. These analogies are woven into the concepts of progressive and regressive developmental events, and they can be imagined as mechanisms that result in either gain or loss of function (e.g., a house addition might equal new neurons or new projections) or maximize efficiency and success (pruning of seedlings might equal programmed cell death). Research on increased myelination during adolescence is also discussed." @default.
- W3044508467 created "2020-07-29" @default.
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- W3044508467 date "2019-12-06" @default.
- W3044508467 modified "2023-09-25" @default.
- W3044508467 title "Remodeling the Adolescent Brain" @default.
- W3044508467 doi "https://doi.org/10.1093/oso/9780195314373.003.0003" @default.
- W3044508467 hasPublicationYear "2019" @default.
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