FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3044607575> ?p ?o ?g. }

• W3044607575 endingPage "657" @default.
• W3044607575 startingPage "651" @default.
• W3044607575 abstract "Abstract Long non-coding RNA is an endogenous non-coding RNA that has currently been proved to be an important player in cancer cell biology. In the present study, we investigated the biological role of PHACTR2-AS1 in tongue squamous cell carcinoma (TSCC). PHACTR2-AS1 was preferentially localized in the cytoplasm, and was notably upregulated in TSCC tissues. High PHACTR2-AS1 was correlated with tumour differentiation, metastatic clinical features, relapse and shortened survival time. Depletion of PHACTR2-AS1 did not affect TSCC cell viability and colony formation ability, whereas substantially inhibited cell migration and invasion in vitro and lung metastasis in vivo. Mechanistically, PHACTR2-AS1 could sponge miR-137 to increase Snail expression, resulting in triggering epithelial–mesenchymal transition process, thereby promoting TSCC cell metastasis. Taken together, our data for the first time elucidate the metastasis-promoting role of PHACTR2-AS1 in TSCC, hinting a new therapeutic target for metastatic TSCC patients." @default.
• W3044607575 created "2020-07-29" @default.
• W3044607575 creator A5017438567 @default.
• W3044607575 creator A5017489902 @default.
• W3044607575 creator A5019769690 @default.
• W3044607575 creator A5023730987 @default.
• W3044607575 creator A5044027684 @default.
• W3044607575 creator A5057216643 @default.
• W3044607575 creator A5091437369 @default.
• W3044607575 date "2020-07-23" @default.
• W3044607575 modified "2023-09-29" @default.
• W3044607575 title "Long non-coding RNA PHACTR2-AS1 promotes tongue squamous cell carcinoma metastasis by regulating Snail" @default.
• W3044607575 cites W1578004457 @default.
• W3044607575 cites W1988581256 @default.
• W3044607575 cites W2198153867 @default.
• W3044607575 cites W2607244245 @default.
• W3044607575 cites W2744518886 @default.
• W3044607575 cites W2765241643 @default.
• W3044607575 cites W2773620963 @default.
• W3044607575 cites W2784570320 @default.
• W3044607575 cites W2791912972 @default.
• W3044607575 cites W2799898775 @default.
• W3044607575 cites W2811451226 @default.
• W3044607575 cites W2897860501 @default.
• W3044607575 cites W2907156774 @default.
• W3044607575 cites W2922279325 @default.
• W3044607575 cites W3006896848 @default.
• W3044607575 cites W3016292171 @default.
• W3044607575 cites W3019137969 @default.
• W3044607575 cites W3020208951 @default.
• W3044607575 cites W3027193954 @default.
• W3044607575 cites W3034143654 @default.
• W3044607575 cites W4211233744 @default.
• W3044607575 doi "https://doi.org/10.1093/jb/mvaa082" @default.
• W3044607575 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32702100" @default.
• W3044607575 hasPublicationYear "2020" @default.
• W3044607575 type Work @default.
• W3044607575 sameAs 3044607575 @default.
• W3044607575 citedByCount "11" @default.
• W3044607575 countsByYear W30446075752020 @default.
• W3044607575 countsByYear W30446075752021 @default.
• W3044607575 countsByYear W30446075752022 @default.
• W3044607575 countsByYear W30446075752023 @default.
• W3044607575 crossrefType "journal-article" @default.
• W3044607575 hasAuthorship W3044607575A5017438567 @default.
• W3044607575 hasAuthorship W3044607575A5017489902 @default.
• W3044607575 hasAuthorship W3044607575A5019769690 @default.
• W3044607575 hasAuthorship W3044607575A5023730987 @default.
• W3044607575 hasAuthorship W3044607575A5044027684 @default.
• W3044607575 hasAuthorship W3044607575A5057216643 @default.
• W3044607575 hasAuthorship W3044607575A5091437369 @default.
• W3044607575 hasConcept C104317684 @default.
• W3044607575 hasConcept C121608353 @default.
• W3044607575 hasConcept C127561419 @default.
• W3044607575 hasConcept C137738243 @default.
• W3044607575 hasConcept C1491633281 @default.
• W3044607575 hasConcept C18903297 @default.
• W3044607575 hasConcept C190062978 @default.
• W3044607575 hasConcept C2779013556 @default.
• W3044607575 hasConcept C2779965526 @default.
• W3044607575 hasConcept C502942594 @default.
• W3044607575 hasConcept C54355233 @default.
• W3044607575 hasConcept C55493867 @default.
• W3044607575 hasConcept C62203573 @default.
• W3044607575 hasConcept C67705224 @default.
• W3044607575 hasConcept C81885089 @default.
• W3044607575 hasConcept C86803240 @default.
• W3044607575 hasConcept C95444343 @default.
• W3044607575 hasConceptScore W3044607575C104317684 @default.
• W3044607575 hasConceptScore W3044607575C121608353 @default.
• W3044607575 hasConceptScore W3044607575C127561419 @default.
• W3044607575 hasConceptScore W3044607575C137738243 @default.
• W3044607575 hasConceptScore W3044607575C1491633281 @default.
• W3044607575 hasConceptScore W3044607575C18903297 @default.
• W3044607575 hasConceptScore W3044607575C190062978 @default.
• W3044607575 hasConceptScore W3044607575C2779013556 @default.
• W3044607575 hasConceptScore W3044607575C2779965526 @default.
• W3044607575 hasConceptScore W3044607575C502942594 @default.
• W3044607575 hasConceptScore W3044607575C54355233 @default.
• W3044607575 hasConceptScore W3044607575C55493867 @default.
• W3044607575 hasConceptScore W3044607575C62203573 @default.
• W3044607575 hasConceptScore W3044607575C67705224 @default.
• W3044607575 hasConceptScore W3044607575C81885089 @default.
• W3044607575 hasConceptScore W3044607575C86803240 @default.
• W3044607575 hasConceptScore W3044607575C95444343 @default.
• W3044607575 hasIssue "6" @default.
• W3044607575 hasLocation W30446075751 @default.
• W3044607575 hasOpenAccess W3044607575 @default.
• W3044607575 hasPrimaryLocation W30446075751 @default.
• W3044607575 hasRelatedWork W2048776092 @default.
• W3044607575 hasRelatedWork W2086968193 @default.
• W3044607575 hasRelatedWork W2614825660 @default.
• W3044607575 hasRelatedWork W2937312570 @default.
• W3044607575 hasRelatedWork W2981288050 @default.
• W3044607575 hasRelatedWork W2983347922 @default.
• W3044607575 hasRelatedWork W3022659872 @default.
• W3044607575 hasRelatedWork W3044607575 @default.
• W3044607575 hasRelatedWork W3112085839 @default.

• next