Matches in SemOpenAlex for { <https://semopenalex.org/work/W3044614511> ?p ?o ?g. }
Showing items 1 to 96 of
96
with 100 items per page.
- W3044614511 endingPage "52" @default.
- W3044614511 startingPage "44" @default.
- W3044614511 abstract "Galphimia gracilis Bartl. (Family- Malpighiaceae) is known as gold shower and available almost everywhere in Bangladesh. This plant has some medicinal properties and is used as a source of vitamins. The current study was designed to evaluate in vitro antioxidant, brine shrimp lethality and antimicrobial activities of methanol (GSM), ethyl-acetate (GSEA) and petroleum ether (GSPE) extracts of G. gracilis stem. In vitro antioxidant activity of the extracts were studied using DPPH radical scavenging assay, NO scavenging assay, total phenol, total flavonoid content, total antioxidant capacity, total tannin content and lipid peroxidation in human erythrocyte cell assays. Lethality bioassay was performed on Artemia salina Leach nauplii. Antimicrobial activity was investigated by disc diffusion technique. Presence of alkaloids, carbohydrates, flavonoids, steroids, terpenoids, tannins, saponins and glycosides were identified in the extracts. Ethyl-acetate extract showed highest activities in DPPH (IC50 22.82±0.172 μg/ml), NO (IC50 72.886±0.394 μg/ml) and total antioxidant assay (210.86±3.436 mg/gm Ascorbic Acid Equivalent). Methanol extract showed highest content in total phenol (972.02±4.56 mg/g Gallic Acid Equivalent), total flavonoid (135.98±1.103 mg/g Quercetin Equivalent) and total tannin content assays (111.454±1.462 mg/g Tannic Acid Equivalent). Ethyl acetate extract showed promising reducing capacity than other extracts in cupric reducing (correlation coefficient r= 0.99 and P<0.01) and reducing power capacity assays (r= 0.99 and P<0.001). Besides, it showed dose dependent activity in both assays. In brine shrimp lethality bioassay, methanol extract was found to be more potent than other extracts (LC50=58.583 μg/ml, χ2=170.967, P<0.001). In disk diffusion technique methanol extract showed highest zone of inhibition against maximum number of microorganisms Staphylococcus aureus, Salmonella typhi, Salmonella abony and Pseudomonas aeruginosa (6.75±0.353 mm). The present findings suggest that the stem extracts of G. gracilis can be used as a source of potential candidates for lead compounds." @default.
- W3044614511 created "2020-07-29" @default.
- W3044614511 creator A5022664738 @default.
- W3044614511 creator A5032927462 @default.
- W3044614511 creator A5048131784 @default.
- W3044614511 creator A5050703953 @default.
- W3044614511 creator A5057471584 @default.
- W3044614511 creator A5068241096 @default.
- W3044614511 creator A5081961122 @default.
- W3044614511 creator A5083158962 @default.
- W3044614511 date "2016-10-10" @default.
- W3044614511 modified "2023-09-25" @default.
- W3044614511 title "ANTIOXIDANT, BRINE SHRIMP LETHALITY AND ANTIMICROBIAL ACTIVITIES OF DIFFERENT EXTRACTS OF GALPHIMIA GRACILIS BARTL. STEM USING IN VITRO ASSAY MODELS" @default.
- W3044614511 cites W1651239900 @default.
- W3044614511 hasPublicationYear "2016" @default.
- W3044614511 type Work @default.
- W3044614511 sameAs 3044614511 @default.
- W3044614511 citedByCount "0" @default.
- W3044614511 crossrefType "journal-article" @default.
- W3044614511 hasAuthorship W3044614511A5022664738 @default.
- W3044614511 hasAuthorship W3044614511A5032927462 @default.
- W3044614511 hasAuthorship W3044614511A5048131784 @default.
- W3044614511 hasAuthorship W3044614511A5050703953 @default.
- W3044614511 hasAuthorship W3044614511A5057471584 @default.
- W3044614511 hasAuthorship W3044614511A5068241096 @default.
- W3044614511 hasAuthorship W3044614511A5081961122 @default.
- W3044614511 hasAuthorship W3044614511A5083158962 @default.
- W3044614511 hasConcept C178790620 @default.
- W3044614511 hasConcept C185592680 @default.
- W3044614511 hasConcept C2775873308 @default.
- W3044614511 hasConcept C2778004101 @default.
- W3044614511 hasConcept C2778362808 @default.
- W3044614511 hasConcept C2779054382 @default.
- W3044614511 hasConcept C2779858419 @default.
- W3044614511 hasConcept C2780309462 @default.
- W3044614511 hasConcept C2781201647 @default.
- W3044614511 hasConcept C2781263971 @default.
- W3044614511 hasConcept C2781393965 @default.
- W3044614511 hasConcept C2781401929 @default.
- W3044614511 hasConcept C29730261 @default.
- W3044614511 hasConcept C2986274086 @default.
- W3044614511 hasConcept C31903555 @default.
- W3044614511 hasConcept C43617362 @default.
- W3044614511 hasConcept C55493867 @default.
- W3044614511 hasConcept C556039675 @default.
- W3044614511 hasConcept C71924100 @default.
- W3044614511 hasConceptScore W3044614511C178790620 @default.
- W3044614511 hasConceptScore W3044614511C185592680 @default.
- W3044614511 hasConceptScore W3044614511C2775873308 @default.
- W3044614511 hasConceptScore W3044614511C2778004101 @default.
- W3044614511 hasConceptScore W3044614511C2778362808 @default.
- W3044614511 hasConceptScore W3044614511C2779054382 @default.
- W3044614511 hasConceptScore W3044614511C2779858419 @default.
- W3044614511 hasConceptScore W3044614511C2780309462 @default.
- W3044614511 hasConceptScore W3044614511C2781201647 @default.
- W3044614511 hasConceptScore W3044614511C2781263971 @default.
- W3044614511 hasConceptScore W3044614511C2781393965 @default.
- W3044614511 hasConceptScore W3044614511C2781401929 @default.
- W3044614511 hasConceptScore W3044614511C29730261 @default.
- W3044614511 hasConceptScore W3044614511C2986274086 @default.
- W3044614511 hasConceptScore W3044614511C31903555 @default.
- W3044614511 hasConceptScore W3044614511C43617362 @default.
- W3044614511 hasConceptScore W3044614511C55493867 @default.
- W3044614511 hasConceptScore W3044614511C556039675 @default.
- W3044614511 hasConceptScore W3044614511C71924100 @default.
- W3044614511 hasIssue "22" @default.
- W3044614511 hasLocation W30446145111 @default.
- W3044614511 hasOpenAccess W3044614511 @default.
- W3044614511 hasPrimaryLocation W30446145111 @default.
- W3044614511 hasRelatedWork W1985616332 @default.
- W3044614511 hasRelatedWork W2039731461 @default.
- W3044614511 hasRelatedWork W2065885942 @default.
- W3044614511 hasRelatedWork W2145762637 @default.
- W3044614511 hasRelatedWork W2158069197 @default.
- W3044614511 hasRelatedWork W2181483873 @default.
- W3044614511 hasRelatedWork W2185914596 @default.
- W3044614511 hasRelatedWork W2208174699 @default.
- W3044614511 hasRelatedWork W2331574717 @default.
- W3044614511 hasRelatedWork W2507048524 @default.
- W3044614511 hasRelatedWork W2547146714 @default.
- W3044614511 hasRelatedWork W2552507950 @default.
- W3044614511 hasRelatedWork W2563807263 @default.
- W3044614511 hasRelatedWork W2765994922 @default.
- W3044614511 hasRelatedWork W2998551914 @default.
- W3044614511 hasRelatedWork W3030160091 @default.
- W3044614511 hasRelatedWork W3092223762 @default.
- W3044614511 hasRelatedWork W3094321152 @default.
- W3044614511 hasRelatedWork W2188903381 @default.
- W3044614511 hasRelatedWork W2560692526 @default.
- W3044614511 hasVolume "6" @default.
- W3044614511 isParatext "false" @default.
- W3044614511 isRetracted "false" @default.
- W3044614511 magId "3044614511" @default.
- W3044614511 workType "article" @default.