Matches in SemOpenAlex for { <https://semopenalex.org/work/W3044647553> ?p ?o ?g. }
- W3044647553 endingPage "15491" @default.
- W3044647553 startingPage "15478" @default.
- W3044647553 abstract "Background Dementia, and in particular Alzheimer's disease (AD), is a debilitating progressive disease with high prevalence in our society. Vitamin B12 and folate deficiency are potential modifiable risk factors. However, previous studies reported inconsistent results. Results The average concentrations of all biochemical markers were within the respective reference ranges. Cross-sectional and longitudinal analyses did not reveal significant associations between biochemical markers and cognitive function, global or regional brain volume, cortical thickness or cortical surface area, neither in controls nor in AD patients. Conclusions Variations of direct and indirect markers of B12 and folate status are not associated with cognitive dysfunction and brain atrophy. Methods This retrospective study explored the association between biochemical markers of B12 and folate status, cognitive function and MRI-based brain atrophy in cognitive normal elderly (controls) and AD patients. Folate, total and active vitamin B12 and MMA were measured in blood samples from 378 controls and 217 AD patients. Neuropsychiatric tests capturing memory, executive function and visuopractical skills were performed in all participants. Brain atrophy was assessed by MRI in 155 controls and 217 AD patients. In a subset of participants cognitive testing (n=234) and MRI (n=182) was repeated after an average median between 1.25 and 6.25 years." @default.
- W3044647553 created "2020-07-29" @default.
- W3044647553 creator A5012543104 @default.
- W3044647553 creator A5017902933 @default.
- W3044647553 creator A5030166869 @default.
- W3044647553 creator A5036911759 @default.
- W3044647553 creator A5044647308 @default.
- W3044647553 creator A5061377482 @default.
- W3044647553 creator A5062622106 @default.
- W3044647553 creator A5068558302 @default.
- W3044647553 creator A5083549305 @default.
- W3044647553 date "2020-07-24" @default.
- W3044647553 modified "2023-10-16" @default.
- W3044647553 title "The impact of folate and vitamin B12 status on cognitive function and brain atrophy in healthy elderly and demented Austrians, a retrospective cohort study" @default.
- W3044647553 cites W1853908050 @default.
- W3044647553 cites W1969187422 @default.
- W3044647553 cites W1999836898 @default.
- W3044647553 cites W2004293194 @default.
- W3044647553 cites W2030818783 @default.
- W3044647553 cites W2048878685 @default.
- W3044647553 cites W2051484514 @default.
- W3044647553 cites W2053265279 @default.
- W3044647553 cites W2059407754 @default.
- W3044647553 cites W2082419882 @default.
- W3044647553 cites W2097664820 @default.
- W3044647553 cites W2103535459 @default.
- W3044647553 cites W2118076374 @default.
- W3044647553 cites W2127724524 @default.
- W3044647553 cites W2134824125 @default.
- W3044647553 cites W2136057401 @default.
- W3044647553 cites W2136284582 @default.
- W3044647553 cites W2147941893 @default.
- W3044647553 cites W2151721316 @default.
- W3044647553 cites W2151860672 @default.
- W3044647553 cites W2155179405 @default.
- W3044647553 cites W2156635660 @default.
- W3044647553 cites W2161568765 @default.
- W3044647553 cites W2345043880 @default.
- W3044647553 cites W2464566210 @default.
- W3044647553 cites W2538258112 @default.
- W3044647553 cites W2663789905 @default.
- W3044647553 cites W2735994029 @default.
- W3044647553 cites W2806395345 @default.
- W3044647553 cites W2933621425 @default.
- W3044647553 cites W2964117437 @default.
- W3044647553 cites W3014251530 @default.
- W3044647553 doi "https://doi.org/10.18632/aging.103714" @default.
- W3044647553 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7467363" @default.
- W3044647553 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32706338" @default.
- W3044647553 hasPublicationYear "2020" @default.
- W3044647553 type Work @default.
- W3044647553 sameAs 3044647553 @default.
- W3044647553 citedByCount "5" @default.
- W3044647553 countsByYear W30446475532020 @default.
- W3044647553 countsByYear W30446475532021 @default.
- W3044647553 countsByYear W30446475532022 @default.
- W3044647553 crossrefType "journal-article" @default.
- W3044647553 hasAuthorship W3044647553A5012543104 @default.
- W3044647553 hasAuthorship W3044647553A5017902933 @default.
- W3044647553 hasAuthorship W3044647553A5030166869 @default.
- W3044647553 hasAuthorship W3044647553A5036911759 @default.
- W3044647553 hasAuthorship W3044647553A5044647308 @default.
- W3044647553 hasAuthorship W3044647553A5061377482 @default.
- W3044647553 hasAuthorship W3044647553A5062622106 @default.
- W3044647553 hasAuthorship W3044647553A5068558302 @default.
- W3044647553 hasAuthorship W3044647553A5083549305 @default.
- W3044647553 hasBestOaLocation W30446475531 @default.
- W3044647553 hasConcept C118552586 @default.
- W3044647553 hasConcept C126322002 @default.
- W3044647553 hasConcept C15744967 @default.
- W3044647553 hasConcept C167135981 @default.
- W3044647553 hasConcept C169760540 @default.
- W3044647553 hasConcept C169900460 @default.
- W3044647553 hasConcept C187212893 @default.
- W3044647553 hasConcept C201903717 @default.
- W3044647553 hasConcept C2779134260 @default.
- W3044647553 hasConcept C2779483572 @default.
- W3044647553 hasConcept C2779750884 @default.
- W3044647553 hasConcept C2781172350 @default.
- W3044647553 hasConcept C3018390542 @default.
- W3044647553 hasConcept C71924100 @default.
- W3044647553 hasConcept C72563966 @default.
- W3044647553 hasConcept C74909509 @default.
- W3044647553 hasConceptScore W3044647553C118552586 @default.
- W3044647553 hasConceptScore W3044647553C126322002 @default.
- W3044647553 hasConceptScore W3044647553C15744967 @default.
- W3044647553 hasConceptScore W3044647553C167135981 @default.
- W3044647553 hasConceptScore W3044647553C169760540 @default.
- W3044647553 hasConceptScore W3044647553C169900460 @default.
- W3044647553 hasConceptScore W3044647553C187212893 @default.
- W3044647553 hasConceptScore W3044647553C201903717 @default.
- W3044647553 hasConceptScore W3044647553C2779134260 @default.
- W3044647553 hasConceptScore W3044647553C2779483572 @default.
- W3044647553 hasConceptScore W3044647553C2779750884 @default.
- W3044647553 hasConceptScore W3044647553C2781172350 @default.
- W3044647553 hasConceptScore W3044647553C3018390542 @default.
- W3044647553 hasConceptScore W3044647553C71924100 @default.
- W3044647553 hasConceptScore W3044647553C72563966 @default.