FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3044654871> ?p ?o ?g. }

• W3044654871 endingPage "536" @default.
• W3044654871 startingPage "525" @default.
• W3044654871 abstract "Sleep problems in middle-aged and older women are very common and have been associated with menopause-related changes in estrogen levels. However, not all women experience sleep problems as they enter perimenopause, and epigenetic mechanisms might contribute to the differences in sleep quality within this population. In this study, we hypothesized that increased methylation of two estrogen receptor (ER) genes (ESR1 and GPER) would be associated with increased sleep problems in healthy pre-, peri-, and postmenopausal women, either directly or indirectly through the experience of vasomotor symptoms (VMS).In 130 healthy women aged 40-73 years, we assessed DNA methylation from dried blood spots (DBS). Women rated their sleep quality using the Pittsburgh Sleep Quality Index (PSQI), and VMS using the Menopause Rating Scale (MRS).Higher percentage methylation of ESR1 was associated with increased sleep problems, mediated by VMS, even after controlling for age, menopausal status, body mass index, estradiol levels, depressive symptoms, and caffeine consumption. There was no significant association between GPER methylation and either sleep problems or VMS.The study findings support an association between increased ESR1 methylation and sleep problems through increased VMS among healthy women aged 40-73 years." @default.
• W3044654871 created "2020-07-29" @default.
• W3044654871 creator A5031189541 @default.
• W3044654871 creator A5049414539 @default.
• W3044654871 creator A5083651506 @default.
• W3044654871 creator A5086305259 @default.
• W3044654871 date "2020-07-01" @default.
• W3044654871 modified "2023-10-05" @default.
• W3044654871 title "<p>Sleep and Methylation of Estrogen Receptor Genes, <em>ESR1</em> and <em>GPER</em>, in Healthy Middle-Aged and Older Women: Findings from the Women 40+ Healthy Aging Study</p>" @default.
• W3044654871 cites W121016599 @default.
• W3044654871 cites W1510616780 @default.
• W3044654871 cites W1542208531 @default.
• W3044654871 cites W1580051413 @default.
• W3044654871 cites W1583611596 @default.
• W3044654871 cites W1601020103 @default.
• W3044654871 cites W1738949154 @default.
• W3044654871 cites W1779686469 @default.
• W3044654871 cites W1812235839 @default.
• W3044654871 cites W1913092771 @default.
• W3044654871 cites W1966475943 @default.
• W3044654871 cites W1970671261 @default.
• W3044654871 cites W1973331597 @default.
• W3044654871 cites W1984977749 @default.
• W3044654871 cites W2001738948 @default.
• W3044654871 cites W2014187001 @default.
• W3044654871 cites W2014804139 @default.
• W3044654871 cites W2025377042 @default.
• W3044654871 cites W2030417265 @default.
• W3044654871 cites W2041454543 @default.
• W3044654871 cites W2047321638 @default.
• W3044654871 cites W2048117553 @default.
• W3044654871 cites W2049100937 @default.
• W3044654871 cites W2052772134 @default.
• W3044654871 cites W2062923679 @default.
• W3044654871 cites W2064316063 @default.
• W3044654871 cites W2064516418 @default.
• W3044654871 cites W2065559115 @default.
• W3044654871 cites W2069121673 @default.
• W3044654871 cites W2075443461 @default.
• W3044654871 cites W2082578282 @default.
• W3044654871 cites W2090700268 @default.
• W3044654871 cites W2091998301 @default.
• W3044654871 cites W2103990329 @default.
• W3044654871 cites W2104017695 @default.
• W3044654871 cites W2112778345 @default.
• W3044654871 cites W2117398145 @default.
• W3044654871 cites W2119270722 @default.
• W3044654871 cites W2120572713 @default.
• W3044654871 cites W2127306096 @default.
• W3044654871 cites W2131271579 @default.
• W3044654871 cites W2137272726 @default.
• W3044654871 cites W2139122477 @default.
• W3044654871 cites W2140445777 @default.
• W3044654871 cites W2141118708 @default.
• W3044654871 cites W2151487996 @default.
• W3044654871 cites W2153157873 @default.
• W3044654871 cites W2156331665 @default.
• W3044654871 cites W2161857374 @default.
• W3044654871 cites W2165167263 @default.
• W3044654871 cites W2171161022 @default.
• W3044654871 cites W2395556627 @default.
• W3044654871 cites W2396988103 @default.
• W3044654871 cites W2491158000 @default.
• W3044654871 cites W2493808054 @default.
• W3044654871 cites W2505166506 @default.
• W3044654871 cites W2524594675 @default.
• W3044654871 cites W2554011250 @default.
• W3044654871 cites W2563087559 @default.
• W3044654871 cites W2564961088 @default.
• W3044654871 cites W2572935401 @default.
• W3044654871 cites W2580488021 @default.
• W3044654871 cites W2585166426 @default.
• W3044654871 cites W2607435391 @default.
• W3044654871 cites W2720150461 @default.
• W3044654871 cites W2739524745 @default.
• W3044654871 cites W2792208831 @default.
• W3044654871 cites W2793154936 @default.
• W3044654871 cites W2802350316 @default.
• W3044654871 cites W2889713233 @default.
• W3044654871 cites W2894645315 @default.
• W3044654871 cites W2904369742 @default.
• W3044654871 cites W2912870907 @default.
• W3044654871 cites W2913887378 @default.
• W3044654871 cites W2922217830 @default.
• W3044654871 cites W2951127676 @default.
• W3044654871 cites W2952786557 @default.
• W3044654871 cites W2973987577 @default.
• W3044654871 cites W2981641891 @default.
• W3044654871 cites W3005402581 @default.
• W3044654871 cites W3027569065 @default.
• W3044654871 cites W4211248975 @default.
• W3044654871 cites W4295990640 @default.
• W3044654871 doi "https://doi.org/10.2147/nss.s256102" @default.
• W3044654871 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7394583" @default.
• W3044654871 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32801978" @default.
• W3044654871 hasPublicationYear "2020" @default.
• W3044654871 type Work @default.
• W3044654871 sameAs 3044654871 @default.

• next