FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3044655093> ?p ?o ?g. }

• W3044655093 abstract "Abstract Purpose To evaluate plasma levels of selected cytokines and investigate their correlation with choroidal thickness (CT) in patients with acute and chronic central serous chorioretinopathy (CSC). Methods We enrolled 30 patients with acute CSC, 30 patients with chronic CSC and 20 controls. Plasma concentrations of 12 cytokines, interleukins IL‐8, IL‐1β, IL‐2, IL‐4, IL‐5, IL‐6, IL‐10 and IL‐12 p70, granulocyte‐macrophage colony‐stimulating factor, interferon‐γ, tumour necrosis factor‐α (TNF‐α) and vascular endothelial growth factor (VEGF), were measured using multiplex immunoassays. Differences in cytokine levels between groups were assessed. We also investigated correlations between cytokine levels and CT using swept‐source optical coherence tomography, as well as an association between plasma cytokine profile and systemic hypertension. Results We noted differences in IL‐6 (p = 0.005), IL‐10 (p = 0.03), IL‐12 p70 (p = 0.028) and VEGF (p = 0.029) levels between groups. Pro‐inflammatory IL‐12 p70 and multidirectional IL‐10 cytokines were upregulated, while pro‐angiogenic VEGF was downregulated in chronic CSC as compared with controls (p = 0.005, p = 0.025 and p = 0.027, respectively). Interleukin‐6 (IL‐6) was upregulated in acute and chronic CSC (p = 0.030 and p = 0.005, respectively). Interleukin‐5 (IL‐5), IL‐6 and IL‐12 levels correlated with mean CT in acute CSC (p = 0.008, p = 0.003 and p = 0.044, respectively), while IL‐8, IL‐6 and TNF‐α plasma levels correlated with hypertension in chronic CSC (p = 0.005, p = 0.033 and p = 0.001, respectively). Conclusion We provided new evidence for the possible role of plasma cytokines in the pathogenesis of CSC. Our results suggest that IL‐6 may be important in the pathophysiology of acute and chronic CSC. The association between inflammatory response and hypertension in patients with CSC was also confirmed." @default.
• W3044655093 created "2020-07-29" @default.
• W3044655093 creator A5013194356 @default.
• W3044655093 creator A5016804155 @default.
• W3044655093 creator A5029495864 @default.
• W3044655093 creator A5039395327 @default.
• W3044655093 creator A5056150470 @default.
• W3044655093 creator A5056329877 @default.
• W3044655093 date "2020-07-23" @default.
• W3044655093 modified "2023-10-18" @default.
• W3044655093 title "Altered plasma cytokine levels in acute and chronic central serous chorioretinopathy" @default.
• W3044655093 cites W1532789752 @default.
• W3044655093 cites W1796417290 @default.
• W3044655093 cites W1925591757 @default.
• W3044655093 cites W1951037154 @default.
• W3044655093 cites W1961628794 @default.
• W3044655093 cites W1988569535 @default.
• W3044655093 cites W2010985903 @default.
• W3044655093 cites W2013108548 @default.
• W3044655093 cites W2017572390 @default.
• W3044655093 cites W2027744674 @default.
• W3044655093 cites W2035181421 @default.
• W3044655093 cites W2038115251 @default.
• W3044655093 cites W2047705499 @default.
• W3044655093 cites W2048638761 @default.
• W3044655093 cites W2054435322 @default.
• W3044655093 cites W2055223304 @default.
• W3044655093 cites W2059258588 @default.
• W3044655093 cites W2063048867 @default.
• W3044655093 cites W2066830734 @default.
• W3044655093 cites W2088898920 @default.
• W3044655093 cites W2093216792 @default.
• W3044655093 cites W2099258317 @default.
• W3044655093 cites W2100224489 @default.
• W3044655093 cites W2106990258 @default.
• W3044655093 cites W2114112168 @default.
• W3044655093 cites W2125014313 @default.
• W3044655093 cites W2126353409 @default.
• W3044655093 cites W2129348353 @default.
• W3044655093 cites W2151703860 @default.
• W3044655093 cites W2161485037 @default.
• W3044655093 cites W2164123970 @default.
• W3044655093 cites W2171818522 @default.
• W3044655093 cites W2319990100 @default.
• W3044655093 cites W2320616723 @default.
• W3044655093 cites W2443553593 @default.
• W3044655093 cites W2470657018 @default.
• W3044655093 cites W2471864054 @default.
• W3044655093 cites W2514622389 @default.
• W3044655093 cites W2531141997 @default.
• W3044655093 cites W256057662 @default.
• W3044655093 cites W2584573662 @default.
• W3044655093 cites W2594500087 @default.
• W3044655093 cites W2604774957 @default.
• W3044655093 cites W2765285330 @default.
• W3044655093 cites W2767373868 @default.
• W3044655093 cites W2774056060 @default.
• W3044655093 cites W2789682868 @default.
• W3044655093 cites W2809022050 @default.
• W3044655093 cites W2809745482 @default.
• W3044655093 cites W2883527219 @default.
• W3044655093 cites W2886521964 @default.
• W3044655093 cites W2890082126 @default.
• W3044655093 cites W2903202909 @default.
• W3044655093 cites W2905083931 @default.
• W3044655093 cites W2915000955 @default.
• W3044655093 cites W2947783140 @default.
• W3044655093 cites W2954100397 @default.
• W3044655093 cites W2980468199 @default.
• W3044655093 cites W2993224278 @default.
• W3044655093 cites W3004071630 @default.
• W3044655093 cites W417772227 @default.
• W3044655093 cites W4211027220 @default.
• W3044655093 doi "https://doi.org/10.1111/aos.14547" @default.
• W3044655093 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7984262" @default.
• W3044655093 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32701204" @default.
• W3044655093 hasPublicationYear "2020" @default.
• W3044655093 type Work @default.
• W3044655093 sameAs 3044655093 @default.
• W3044655093 citedByCount "19" @default.
• W3044655093 countsByYear W30446550932021 @default.
• W3044655093 countsByYear W30446550932022 @default.
• W3044655093 countsByYear W30446550932023 @default.
• W3044655093 crossrefType "journal-article" @default.
• W3044655093 hasAuthorship W3044655093A5013194356 @default.
• W3044655093 hasAuthorship W3044655093A5016804155 @default.
• W3044655093 hasAuthorship W3044655093A5029495864 @default.
• W3044655093 hasAuthorship W3044655093A5039395327 @default.
• W3044655093 hasAuthorship W3044655093A5056150470 @default.
• W3044655093 hasAuthorship W3044655093A5056329877 @default.
• W3044655093 hasBestOaLocation W30446550931 @default.
• W3044655093 hasConcept C11988809 @default.
• W3044655093 hasConcept C126322002 @default.
• W3044655093 hasConcept C150173356 @default.
• W3044655093 hasConcept C167734588 @default.
• W3044655093 hasConcept C17991360 @default.
• W3044655093 hasConcept C187316574 @default.
• W3044655093 hasConcept C203014093 @default.
• W3044655093 hasConcept C2777025900 @default.
• W3044655093 hasConcept C2778690821 @default.

• next