Matches in SemOpenAlex for { <https://semopenalex.org/work/W3044874310> ?p ?o ?g. }
- W3044874310 abstract "Abstract Human movement occurs through contraction of the basic unit of the muscle cell, the sarcomere. Sarcomeres have long been considered to be arranged end-to-end in series along the length of the muscle into tube-like myofibrils with many individual, parallel myofibrils comprising the bulk of the muscle cell volume. Here, we demonstrate that striated muscle cells form a continuous myofibrillar matrix linked together by frequently branching sarcomeres. We find that all muscle cells contain highly connected myofibrillar networks though the frequency of sarcomere branching goes down from early to late postnatal development and is higher in slow-twitch than fast-twitch mature muscles. Moreover, we show that the myofibrillar matrix is united across the entire width of the muscle cell both at birth and in mature muscle. We propose that striated muscle force is generated by a singular, mesh-like myofibrillar network rather than many individual, parallel myofibrils." @default.
- W3044874310 created "2020-07-29" @default.
- W3044874310 creator A5039749094 @default.
- W3044874310 creator A5041810645 @default.
- W3044874310 creator A5068287768 @default.
- W3044874310 creator A5085775544 @default.
- W3044874310 creator A5086554572 @default.
- W3044874310 date "2020-07-24" @default.
- W3044874310 modified "2023-09-25" @default.
- W3044874310 title "The unified myofibrillar matrix for force generation in muscle" @default.
- W3044874310 cites W1766184155 @default.
- W3044874310 cites W1965336601 @default.
- W3044874310 cites W1965883224 @default.
- W3044874310 cites W1975182135 @default.
- W3044874310 cites W1975714515 @default.
- W3044874310 cites W1979148672 @default.
- W3044874310 cites W1995128238 @default.
- W3044874310 cites W1997767315 @default.
- W3044874310 cites W2008116454 @default.
- W3044874310 cites W2029750350 @default.
- W3044874310 cites W2031371653 @default.
- W3044874310 cites W2033359534 @default.
- W3044874310 cites W2035499535 @default.
- W3044874310 cites W2035771990 @default.
- W3044874310 cites W2038537781 @default.
- W3044874310 cites W2043867671 @default.
- W3044874310 cites W2044361401 @default.
- W3044874310 cites W2045782192 @default.
- W3044874310 cites W2048802580 @default.
- W3044874310 cites W2055535789 @default.
- W3044874310 cites W2055694197 @default.
- W3044874310 cites W2087969022 @default.
- W3044874310 cites W2089114409 @default.
- W3044874310 cites W2089490125 @default.
- W3044874310 cites W2103358381 @default.
- W3044874310 cites W2116989625 @default.
- W3044874310 cites W2125908423 @default.
- W3044874310 cites W2153661901 @default.
- W3044874310 cites W2164549722 @default.
- W3044874310 cites W2191896778 @default.
- W3044874310 cites W2216126212 @default.
- W3044874310 cites W2275437472 @default.
- W3044874310 cites W2326712047 @default.
- W3044874310 cites W2333620852 @default.
- W3044874310 cites W2606122737 @default.
- W3044874310 cites W2731942167 @default.
- W3044874310 cites W2754007808 @default.
- W3044874310 cites W2771746792 @default.
- W3044874310 cites W2787055137 @default.
- W3044874310 cites W2899636858 @default.
- W3044874310 cites W2914459006 @default.
- W3044874310 cites W2919659463 @default.
- W3044874310 cites W2941378716 @default.
- W3044874310 doi "https://doi.org/10.1038/s41467-020-17579-6" @default.
- W3044874310 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7381600" @default.
- W3044874310 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32709902" @default.
- W3044874310 hasPublicationYear "2020" @default.
- W3044874310 type Work @default.
- W3044874310 sameAs 3044874310 @default.
- W3044874310 citedByCount "43" @default.
- W3044874310 countsByYear W30448743102019 @default.
- W3044874310 countsByYear W30448743102020 @default.
- W3044874310 countsByYear W30448743102021 @default.
- W3044874310 countsByYear W30448743102022 @default.
- W3044874310 countsByYear W30448743102023 @default.
- W3044874310 crossrefType "journal-article" @default.
- W3044874310 hasAuthorship W3044874310A5039749094 @default.
- W3044874310 hasAuthorship W3044874310A5041810645 @default.
- W3044874310 hasAuthorship W3044874310A5068287768 @default.
- W3044874310 hasAuthorship W3044874310A5085775544 @default.
- W3044874310 hasAuthorship W3044874310A5086554572 @default.
- W3044874310 hasBestOaLocation W30448743101 @default.
- W3044874310 hasConcept C105702510 @default.
- W3044874310 hasConcept C12554922 @default.
- W3044874310 hasConcept C125705527 @default.
- W3044874310 hasConcept C134018914 @default.
- W3044874310 hasConcept C163415756 @default.
- W3044874310 hasConcept C174054327 @default.
- W3044874310 hasConcept C185592680 @default.
- W3044874310 hasConcept C207200792 @default.
- W3044874310 hasConcept C2776050358 @default.
- W3044874310 hasConcept C2778996579 @default.
- W3044874310 hasConcept C55493867 @default.
- W3044874310 hasConcept C68731436 @default.
- W3044874310 hasConcept C7301908 @default.
- W3044874310 hasConcept C86803240 @default.
- W3044874310 hasConcept C95444343 @default.
- W3044874310 hasConceptScore W3044874310C105702510 @default.
- W3044874310 hasConceptScore W3044874310C12554922 @default.
- W3044874310 hasConceptScore W3044874310C125705527 @default.
- W3044874310 hasConceptScore W3044874310C134018914 @default.
- W3044874310 hasConceptScore W3044874310C163415756 @default.
- W3044874310 hasConceptScore W3044874310C174054327 @default.
- W3044874310 hasConceptScore W3044874310C185592680 @default.
- W3044874310 hasConceptScore W3044874310C207200792 @default.
- W3044874310 hasConceptScore W3044874310C2776050358 @default.
- W3044874310 hasConceptScore W3044874310C2778996579 @default.
- W3044874310 hasConceptScore W3044874310C55493867 @default.
- W3044874310 hasConceptScore W3044874310C68731436 @default.
- W3044874310 hasConceptScore W3044874310C7301908 @default.