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• W3044892440 endingPage "57" @default.
• W3044892440 startingPage "48" @default.
• W3044892440 abstract "Psidium friedrichsthalianum fruits have in vitro antioxidant activity and their intake has been suggested to have potential health benefits; however, there is still no evidence on the potential in vivo effect of their consumption. We aim to study the effect of the oral administration of a P. friedrichsthalianum juice on the urinary metabolome of adult male Wistar rats. Acute and short-term interventions were carried out and urine sample metabolites were analyzed in a 600 MHz NMR instrument with a NOESY-presat sequence.and post-treatment effects were identified by comparison against control conditions. Acute administration caused a decrease in the excretion of citrate and allantoin in the 0 to 6 h period and citrate and α-ketoglutarate in the 6 to 12 h period. Lactate and Krebs cycle intermediates showed reduced excretion in the 12 to 24 h period. Short-term administration (for 7 days) decreased the excretion of Krebs cycle intermediates together with lactate and allantoin. The effect was stronger after short-term administration suggesting a dose-dependent effect. P. friedrichsthalianum juice caused a change in rat excretion of energy metabolites, probably associated with an increase in aerobic metabolism, suggesting in vivo modulation of the redox balance." @default.
• W3044892440 created "2020-07-29" @default.
• W3044892440 creator A5005895518 @default.
• W3044892440 creator A5015745966 @default.
• W3044892440 creator A5035107577 @default.
• W3044892440 creator A5045237001 @default.
• W3044892440 date "2020-08-01" @default.
• W3044892440 modified "2023-10-18" @default.
• W3044892440 title "Oral administration of Costa Rican guava (Psidium friedrichsthalianum) juice induces changes in urinary excretion of energy-related compounds in Wistar rats determined by 1H NMR" @default.
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• W3044892440 doi "https://doi.org/10.1016/j.nfs.2020.07.003" @default.
• W3044892440 hasPublicationYear "2020" @default.
• W3044892440 type Work @default.

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