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- W3044909403 abstract "Increasing numbers of children and adolescents are travelling to destinations situated at high altitude and are subsequently exposed to altitude-related hypoxia and its potential health risks. Rapid ascent to high-altitude triggers sympathetic activation in adults, which can be detected by measurements of heart rate variability (HRV) and contributes when exaggerated to the pathogenesis of high-altitude pulmonary oedema. Data in children on autonomic regulation after rapid ascent to high altitude are lacking. The aim of this study is to characterise autonomic regulation in healthy children and adolescents during short-term exposure to high altitude. 97 healthy children and adolescents (mean ± SD age, 11.9 ± 2.2 years, range 7–17 years, 47 girls and 50 boys) participated in the study. HRV was measured from 5 minutes ECG recording at low altitude (450 m) and 24 h after arriving at the high altitude research station of the Jungfraujoch in Switzerland (3454 m asl). Time domain analysis demonstrated an increase in heart rate in all subjects from low to high altitude (74 ± 9 vs 97 ± 13 bpm, p" @default.
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- W3044909403 date "2009-06-01" @default.
- W3044909403 modified "2023-09-27" @default.
- W3044909403 title "Autonomic regulation in adolescents after rapid ascent to 3454 metres" @default.
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